scholarly journals Effect of adrenergic-blocking or -stimulating agents on plasma growth hormone, immunoreactive insulin, and blood free fatty acid levels in man

1971 ◽  
Vol 50 (5) ◽  
pp. 1069-1079 ◽  
Author(s):  
Hiroo Imura ◽  
Yuzuru Kato ◽  
Masaki Ikeda ◽  
Masachika Morimoto ◽  
Mikio Yawata
Keyword(s):  
Growth Hormone ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Immunoreactive Insulin ◽  
Plasma Growth Hormone ◽  
Adrenergic Blocking

Effect of insulin on free fatty acid uptake by hepatocytes in the duck

1984 ◽  
Vol 102 (3) ◽  
pp. 381-386 ◽  
Author(s):  
R. Gross ◽  
P. Mialhe
Keyword(s):  
Fatty Acids ◽  
Growth Hormone ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Glucose Metabolism ◽  
Free Fatty Acids ◽  
Fatty Acid Uptake ◽  
Acid Uptake ◽  
Low Doses ◽  
Higher Doses

ABSTRACT To elucidate the hypolipacidaemic effect of insulin in ducks, its action on the uptake of free fatty acids (FFA) by duck hepatocytes was determined. At low doses (10 mu./l) insulin stimulated FFA uptake. This effect was not observed with higher doses of insulin (20, 30 and 50 mu./l). Growth hormone at physiological concentrations and corticosterone (14·4 nmol/l) decreased basal activity, probably by reducing glucose metabolism and consequently α-glycerophosphate (α-GP) supply. Insulin was able to reverse the inhibition induced by GH and corticosterone on both FFA uptake and α-GP production. These results therefore suggest that the hypolipacidaemic effect of insulin may be partly mediated by its action on hepatic FFA uptake. J. Endocr. (1984) 102, 381–386

Plasma Free Fatty Acid Response to the Administration of Chorionic “Growth Hormone-Prolactin”

1966 ◽  
Vol 26 (4) ◽  
pp. 478-482 ◽  
Author(s):  
M. M. GRUMBACH ◽  
S. L. KAPLAN ◽  
C. L. ABRAMS ◽  
J. J. BELL ◽  
F. A. CONTE
Keyword(s):  
Growth Hormone ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Plasma Free Fatty Acid

DIFFERENT EFFECTS OF EXOGENOUS CYCLIC ADENOSINE MONOPHOSPHATE AND ITS DIBUTYRYL DERIVATIVE ON PLASMA GROWTH HORMONE, GLUCOSE, INSULIN AND CORTISOL

1976 ◽  
Vol 83 (1) ◽  
pp. 15-25
Author(s):  
M. Vanderschueren-Lodeweyckx ◽  
W. Proesmans ◽  
E. Eggermont ◽  
R. Eeckels
Keyword(s):  
Growth Hormone ◽  
Hormone Secretion ◽  
Growth Hormone Secretion ◽  
Cyclic Adenosine Monophosphate ◽  
Adenosine Monophosphate ◽  
Normal Subjects ◽  
Immunoreactive Insulin ◽  
Plasma Growth Hormone ◽  
Hormone Levels ◽  
The Mean

ABSTRACT The effects of the infusion in four different dosages (0.001, 0.005, 0.02 and 0.2 mg/kg/min during 60 min) of cyclic 3′,5′-adenosine monophosphate and of its dibutyryl derivative on plasma growth hormone and on glucose, immunoreactive insulin and cortisol were studied in 38 normal subjects and in 10 patients with idiopathic hypopituitarism. In normal subjects cyclic 3′,5′-adenosine monophosphate provokes an increase in plasma growth hormone levels (only when a dosage of 0.2 mg/kg/min is used) without any changes in plasma glucose, insulin and cortisol. The maximal value of the means is observed 75 min after starting the infusion. Dibutyryl cyclic 3′,5′-adenosine monophosphate (0.2 and 0.02 mg/kg/min) provokes a dose-related rise in plasma growth hormone levels which is always preceded by hyperglycaemia and hyperinsulinaemia. The peak of the mean growth hormone levels occurs at 135 min after initiation of the infusion. In all but one hypopituitary patients the nucleotides do not promote growth hormone secretion. It is concluded that exogenous cyclic 3′,5′-adenosine monophosphate and its dibutyryl derivative may not be considered as analogous and that both compounds may contribute to study growth hormone release in normal subjects and in patients with growth abnormalities.

Effect of Obesity on Ambient Plasma Glucose, Free Fatty Acid, Insulin, Growth Hormone, and Glucagon Concentrations*

1986 ◽  
Vol 63 (2) ◽  
pp. 481-484 ◽  
Author(s):  
A. GOLAY ◽  
A.L.M. SWISLOCKI ◽  
Y.D.I. CHEN ◽  
J.B. JASPAN ◽  
G.M. REAVEN
Keyword(s):  
Growth Hormone ◽  
Fatty Acid ◽  
Free Fatty Acid ◽  
Plasma Glucose ◽  
Ambient Plasma
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