scholarly journals MECHANISM AND SIGNIFICANCE OF THE THYMOL TURBIDITY TEST FOR LIVER DISEASE

1947 ◽  
Vol 26 (6) ◽  
pp. 1060-1071 ◽  
Author(s):  
Henry G. Kunkel ◽  
Charles L. Hoagland
Keyword(s):  
Liver Disease ◽  
Thymol Turbidity ◽  
Turbidity Test ◽  
Thymol Turbidity Test

A Study of the Thymol Turbidity Test with Special Reference to Buffer Behavior

1962 ◽  
Vol 8 (5) ◽  
pp. 475-485 ◽  
Author(s):  
John G Reinhold
Keyword(s):  
Serum Lipid ◽  
Large Change ◽  
Critical Importance ◽  
Lipid Concentration ◽  
Thymol Turbidity ◽  
Serum Lipid Concentration ◽  
Turbidity Test ◽  
The Difference ◽  
The Stability ◽  
Thymol Turbidity Test

Abstract Replacement of barbiturate buffer by a tris-hydroxymethylaminomethane buffer in the thymol test reagent of Maclagan greatly improves the stability of the reagent. Thymol turbidity measurements made by means of the modified reagent agreed closely with those made with barbiturate-containing reagents. However in hyperlipemic sera, the latter reagent gave higher turbidities. A reaction of barbiturate with serum chylomicrons and triglycerides explains the difference. It is believed that the modified reagent is less likely to be affected by casual changes in serum lipid concentration and that therefore it should prove to be more dependable as an aid in the study of liver disease. Heating is not an essential operation in preparation of thymol test reagents. The pH is of critical importance in measurement of thymol turbidity. The large change in pH of barbiturate and Tris buffers with change in temperature makes careful control of temperature essential. Tables showing the appropriate reagent pH at various laboratory temperatures are presented.

The Thymol Turbidity Test in Screening of Blood Donors

1957 ◽  
Vol 27 (5) ◽  
pp. 489-502 ◽  
Author(s):  
E. R. Jennings ◽  
W. M. Hindman ◽  
B. Zak ◽  
J. Reed ◽  
O. A. Brines
Keyword(s):  
Blood Donors ◽  
Thymol Turbidity ◽  
Turbidity Test ◽  
Thymol Turbidity Test
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