scholarly journals ELECTROPHORETIC CHANGES IN THE SERUM PROTEIN PATTERNS OF PATIENTS WITH SCARLET FEVER AND RHEUMATIC FEVER 1

1945 ◽  
Vol 24 (5) ◽  
pp. 648-656 ◽  
Author(s):  
Vincent P. Dole ◽  
Robert F. Watson ◽  
Sidney Rothbard ◽  
Esther Braun ◽  
Kenneth Winfield
1959 ◽  
Vol 34 (177) ◽  
pp. 392-397 ◽  
Author(s):  
B. S. Kulkarni ◽  
R. S. Satoskar ◽  
M. N. Parikh ◽  
R. G. Chitre

1968 ◽  
Vol 49 (3) ◽  
pp. 544 ◽  
Author(s):  
Heinrich Bongardt ◽  
Voit B. Richens ◽  
Walter E. Howard

PEDIATRICS ◽  
1948 ◽  
Vol 2 (6) ◽  
pp. 750-750
Author(s):  
P. A. DI SANT' AGNESE

This book represents the most recent attempt to provide a systematic description of the skin manifestations of internal disorders. The author has coined and used throughout the volume the term "dermadrome" to designate the dermal component of a syndrome. Thus for instance the characteristic exanthem is the "dermadrome" of scarlet fever, erythema multiforme and skin nodules the "dermadromes" of rheumatic fever. The dermatologic symptoms are detailed under the heading of the various diseases. This facilitates reference within the text for those not conversant with all the intricacies of dermatologic classification. Author and publisher have done a commendable job in presenting the material in clear and readable form.


1953 ◽  
Vol 84 (3) ◽  
pp. 707-710 ◽  
Author(s):  
C. Hoch-Ligeti ◽  
K. Irvine ◽  
E. P. Sprinkle

1956 ◽  
Vol 2 (1) ◽  
pp. 35-44 ◽  
Author(s):  
Harold B Salt

Abstract Investigations into the serum protein patterns that occur in chronic rheumatic diseases, formerly made by salt-fractionation methods, are now revised with the aid of the superior technic of microelectrophoretic separation. Using the microelectrophoretic method, supplemented by a single salt-fractionation procedure, the concentrations of albumin, α1-globulin, α2-globulin, β-globulin and γ-globulin in the sera of 26 patients variously affected by chronic rheumatic diseases were determined. Normal protein patterns were found in all the 12 sera with normal total globulin content, whereas variously abnormal protein patterns were found in all of the 14 hyperglobulinemic sera. The hyperglobulinemia of chronic rheumatic diseases was found most frequently to be due to increments in γ-globulin, often accompanied also by increases in α2-globulin. Less frequently, increased amounts of β-globulin were found, and in some cases an elevation of α1-globulin. These abnormalities were all detectable electrophoretically, whereas the method for the salting-out of γ-globulin was unsatisfactory.


1948 ◽  
Vol 87 (1) ◽  
pp. 57-70 ◽  
Author(s):  
T. N. Harris

Complement-fixing antibodies to the cytoplasmic particles (CP) and to the S fraction of streptococcal nucleoproteins are present in normal human sera, the range of concentrations varying among the age groups. The titer of these antibodies rises between the first half-week and the 3rd week of scarlet fever, in more than 80 per cent of the cases. The titers then remain elevated for at least 4 months. In children, 91 per cent of the normal sera examined showed anti-CP titers up to 32; 87 per cent of sera in active rheumatic disease had titers above this level. Corresponding data with S fell in the same range of percentage distribution. Anti-CP and anti-S titers remained elevated long after the rheumatic process had reached quiescence. No correlation of serologic titer with the degree of clinical activity was found in the case of either antibody.


1984 ◽  
Vol 30 (5) ◽  
pp. 794-797 ◽  
Author(s):  
W E Neeley

Abstract We describe how a microcomputer (Apple II Plus) can be interfaced with a commercial densitometer to provide control functions, do automated data processing, and print final reports. The amplified densitometer photodetector signal is digitized, stored, and plotted on the cathode-ray tube to provide a real-time graphical display of data acquisition. The software was designed to identify automatically the five main serum protein fractions and to compute final results. Algorithms were designed to provide medically relevant comments for most of the common abnormal protein patterns, and the comments section was designed so that it could be modified to use specific comments composed by the user. A final report, printed in duplicate, contains information such as the patient's name, identifying numbers, numerical results, normal values, medically relevant comments, and a digitized high-resolution plot of the electrophoretic pattern. The densitometer was one that already had been in use for several years; the microcomputer system, software, and interfaces cost less than $2200.


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