scholarly journals Association of Aberrant Posterior Vitreous Detachment and Pathologic Tractional Forces With Myopic Macular Degeneration

2021 ◽  
Vol 62 (7) ◽  
pp. 7
Author(s):  
Kai Yuan Tey ◽  
Qiu Ying Wong ◽  
Yee Shan Dan ◽  
Andrew S. H. Tsai ◽  
Daniel S. W. Ting ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Posterior Vitreous Detachment ◽  
Vitreous Detachment ◽  
Tractional Forces

Effect of posterior vitreous detachment on treat-and-extend versus monthly ranibizumab for neovascular age-related macular degeneration

2019 ◽  
Vol 104 (7) ◽  
pp. 899-903 ◽  
Author(s):  
Sebastian M Waldstein ◽  
Leonard Coulibaly ◽  
Sophie Riedl ◽  
Amir Sadeghipour ◽  
Bianca S Gerendas ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Posterior Vitreous Detachment ◽  
Median Number ◽  
Age Related Macular Degeneration ◽  
Controlled Clinical Trial ◽  
Vitreous Detachment ◽  
Treat And Extend ◽  
Age Related ◽  
Treatment Naïve ◽  
The Impact

AimsTo investigate the impact of posterior vitreous detachment (PVD) on the efficacy of treat-and-extend (T&E) ranibizumab in neovascular age-related macular degeneration.MethodsIn a post hoc analysis of a randomised controlled clinical trial, spectral-domain optical coherence tomography images of treatment-naïve patients randomised to receive T&E (n=265) or monthly (n=264) ranibizumab for 12 months were included. Certified, masked graders diagnosed the presence or the absence of complete PVD. The main outcome measures were the mean change in best-corrected visual acuity (BCVA) and central retinal thickness (CRT) at month 12, the number of administered ranibizumab injections and the proportion of patients extended to more than 8 weeks.ResultsAt baseline, complete PVD was present in 51% and 56% of patients in the monthly and T&E arms, respectively. Mean change in BCVA at month 12 was +9.0 (PVD) vs +9.5 letters (no PVD, p=0.78) in monthly treated eyes, and +6.0 (PVD) vs +7.5 letters (no PVD, p=0.42) in T&E treated eyes. Conversely, mean change in CRT at month 12 was −174 (PVD) vs −173 µm (no PVD, p=0.98) in the monthly arm, and −175 (PVD) vs −164 µm (no PVD, p=0.58) in the T&E arm. In T&E treated patients, the median number of injections was eight vs nine (p=0.035). 71% of PVD eyes were extended successfully, compared with 55% of eyes without PVD (p=0.005).ConclusionPVD was not found to impact functional and anatomical outcomes of T&E ranibizumab therapy. However, patients without a complete PVD required more retreatments and were significantly less likely to be successfully extended.Trial registration numberNCT01948830

Vitreomacular Traction: Pathophysiology, Classification, Clinical Diagnosis, and Treatment

2018 ◽  
pp. 249-255
Keyword(s):  
Eye Movements ◽  
Clinical Diagnosis ◽  
Posterior Vitreous Detachment ◽  
Diagnosis And Treatment ◽  
Wide Area ◽  
Vitreomacular Traction ◽  
Vitreomacular Adhesion ◽  
Vitreous Detachment ◽  
Foveal Detachment ◽  
Tractional Forces

Vitreomacular adhesions between the macula and the cortex may cause complications during the normal posterior vitreous detachment. These adhesions can affect a focal or wide area. Simple vitreomacular adhesion may not alter the macular anatomy. But sometimes these tractional forces can cause vitreomacular tractions with eye movements. This situation leads to distortion of the retina and foveal detachment. This review mentions the Vitreomacular Traction in the main aspects.

scholarly journals The influence of vitreomacular adhesion on the pathogenesis and course of age-related macular degeneration

2013 ◽  
Vol 6 (1) ◽  
pp. 53-60
Author(s):  
Nikita Yuryevich Dal ◽  
Gassan Basharovich Shaar ◽  
Yuriy Sergeyevich Astakhov ◽  
Marina Mikhaylovna Lobanova
Keyword(s):  
Macular Degeneration ◽  
Posterior Vitreous Detachment ◽  
Age Related Macular Degeneration ◽  
Vitreomacular Adhesion ◽  
Vitreous Detachment ◽  
Age Related ◽  
Different Types ◽  
Age Related Changes

This article describes the age-related changes in vitreous and different types of posterior vitreous detachment. Possible effect of normal and pathological posterior vitreous detachment (in particular vitreomacular adhesion and traction syndrome) on the age-related macular degeneration course are considered. Vitrectomy and pharmacological vitreolysis potentials in the treatment of vitreomacular adhesion are discussed.

Standard 6-mm Compared with Widefield 16.5-mm OCT for Staging of Posterior Vitreous Detachment

2020 ◽  
Vol 4 (11) ◽  
pp. 1093-1102 ◽  
Author(s):  
Jessica A. Kraker ◽  
Judy E. Kim ◽  
Elizabeth C. Koller ◽  
Joshua C. George ◽  
Eileen S. Hwang
Keyword(s):  
Posterior Vitreous Detachment ◽  
Vitreous Detachment

Posterior vitreous detachment

2005 ◽  
Vol 117 (3) ◽  
pp. 37-42 ◽  
Author(s):  
Curtis E. Margo ◽  
Lynn E. Harman
Keyword(s):  
Posterior Vitreous Detachment ◽  
Vitreous Detachment
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