scholarly journals Microvasculature Recovery Detected Using Optical Coherence Tomography Angiography and the Rate of Visual Field Progression After Glaucoma Surgery

2021 ◽  
Vol 62 (15) ◽  
pp. 17
Author(s):  
Hae-Young Lopilly Park ◽  
Kyung Euy Hong ◽  
Da Young Shin ◽  
Younhea Jung ◽  
Eun Kyoung Kim ◽  
...  
2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Harsha L. Rao ◽  
Thanemozhi Srinivasan ◽  
Zia S. Pradhan ◽  
Shruthi Sreenivasaiah ◽  
Dhanaraj A.S. Rao ◽  
...  

2020 ◽  
Vol 12 ◽  
pp. 251584141989982
Author(s):  
Giacinto Triolo ◽  
Alessandro Rabiolo

The present review will summarize the most updated findings with regards to optical coherence tomography and optical coherence tomography angiography in glaucoma, highlighting their clinical use for detection and monitoring of the disease, and their correlation to functional tests (such as visual field) widely employed in the asset of modern glaucoma clinics.


2020 ◽  
pp. 112067212092434
Author(s):  
Melike Balikoglu-Yilmaz ◽  
Mahmut Kaya ◽  
Murat Erbezci ◽  
Suleyman Kaynak

Purpose To report the management of accidental macular photocoagulation during a 750-nm Alexandrite laser hair removal procedure. Methods Single case report with images. Results A 23-year-old girl presented with an immediate visual field defect in her right eye after direct inadvertent exposure to a single discharge from a 750-nm Alexandrite laser used for laser hair removal. Baseline Snellen visual acuity was 20/20 in the involved right eye but the patient reported a subjective visual field defect. She was treated with oral methylprednisolone that was started at a dose of 1 mg/kg/day and then gradually reduced. Six months after the initial exposure, the final visual acuity was 20/20 and there was a significant improvement in the macular lesion. However, the subjective visual field defect continued. She underwent multimodal retinal imaging with optical coherence tomography, fundus fluorescence angiography, and optical coherence tomography angiography in addition to a visual field test and microperimety. Conclusion The present case documents a gradual visual and anatomical improvement following macular photic damage after accidental occupational exposure to a 750-nm Alexandrite laser. The treatment should be arranged according to the localization of the laser damage. Optical coherence tomography angiography also has the potential to help noninvasively detect choriocapillaris damage.


Ophthalmology ◽  
2016 ◽  
Vol 123 (12) ◽  
pp. 2498-2508 ◽  
Author(s):  
Adeleh Yarmohammadi ◽  
Linda M. Zangwill ◽  
Alberto Diniz-Filho ◽  
Min Hee Suh ◽  
Siamak Yousefi ◽  
...  

2021 ◽  
pp. bjophthalmol-2020-318166
Author(s):  
Ana Miguel ◽  
André Silva ◽  
Joao Barbosa-Breda ◽  
Luis Azevedo ◽  
Abdulkarim Abdulrahman ◽  
...  

Background/aimsOptical coherence tomography angiography (OCTA) allows the study of vessel density (VD). We intended to perform a systematic review of studies focusing on longitudinal changes in peripapillary and macular VD measurements in glaucoma.MethodsA search was performed across MEDLINE, Scopus, ISI Web of Science and Google Scholar, using the following query from inception until 20 September 2019: ((“optical coherence tomography angiography”[tiab]) OR (optical coherence tomography angiography[MeSH]) OR (“OCTA”[tiab]) OR (“OCT-A”[tiab]) OR (“angio-OCT”[tiab]) OR (“OCT- angiography”[tiab]) OR (“OCT-angio”[tiab]) OR (“OCT-angiographie”[tiab])) AND (glaucom*[tiab] OR glaucoma[MeSH]). Prospective studies that quantitatively assessed the longitudinal changes in VD in glaucoma with at least 3 months of follow-up were included.ResultsTen out of 4516 studies were included. The rate of VD change in glaucoma varied from 0.036/year to 1.08/year and 1.3% to 3.2% per year, with significantly different rates between glaucoma and healthy controls. Five studies assessed VD change after glaucoma surgery, obtaining variable results, ranging from a temporary VD decrease to increase after 3 months. Meta-analysis was not possible due to a wide variation in methods, measurements and region of VD.ConclusionOCTA is a non-invasive technology, which shows promise in glaucoma. Measures should be taken to increase the quality and standardise the methodology of VD measures in OCTA longitudinal studies, for future meta-analyses.


2018 ◽  
Vol 103 (5) ◽  
pp. 585-591 ◽  
Author(s):  
Joong Won Shin ◽  
Junki Kwon ◽  
Jiyun Lee ◽  
Michael S Kook

AimsTo investigate the global and regional relationships between peripapillary vessel density (pVD) and visual field mean sensitivity (VFMS) in glaucomatous eyes with and without high myopia in comparison with those between peripapillary retinal nerve fibre layer thickness (pRNFLT) and VFMS.MethodsA total of 130 eyes from 130 patients with glaucoma consisting of those with and without high myopia were included in a consecutive manner. High myopia was defined as a spherical equivalent <−6.0 dioptres or axial length >26.5 mm. The pVD and pRNFLT were evaluated using optical coherence tomography angiography (OCT-A) and spectral-domain optical coherence tomography. VFMS was assessed using a linear unlogged 1/L scale. The vasculature–function or structure–function relationships were analysed by comparing the pVD or pRNFLT to the corresponding VFMS, according to Garway-Heath map regionalisation.ResultsThe global pVD-VFMS association was significantly stronger than the pRNFLT-VFMS association in glaucomatous eyes with high myopia (p=0.009). However, there were no significant differences between global pVD-VFMS and pRNFLT-VFMS associations in glaucomatous eyes without high myopia (p=0.343). Regionally, the pVD-VFMS association was significantly greater than the pRNFLT-VFMS association at the superonasal, nasal and temporal sectors (all p<0.05) in glaucomatous eyes with high myopia.ConclusionsThe pVD assessment by OCT-A shows a better global and regional correlation with VFMS than a pRNFLT assessment in glaucoma patients with high myopia. The pVD may be a useful parameter in monitoring disease progression of highly myopic glaucomatous eyes.


2018 ◽  
Vol 29 (5) ◽  
pp. 532-537 ◽  
Author(s):  
Dilay Ozek ◽  
Mehmet Onen ◽  
Emine Esra Karaca ◽  
Ahmet Omma ◽  
Ozlem Evren Kemer ◽  
...  

Purpose: The aim of this study is to measure retinal vessel density and thickness of the macula by optical coherence tomography angiography in patients with rheumatoid arthritis taking hydroxychloroquine. Methods: The study included 40 patients with rheumatoid arthritis taking hydroxychloroquine and 20 age-, gender-, and axial length-matched control subjects. Patients were divided into two groups according to the duration of hydroxychloroquine use. Twenty four of the patients were taking hydroxychloroquine for more than 5 years (Group 1), and the rest of 16 were taking hydroxychloroquine for less than 5 years (Group 2). A total of 20 age- and gender-matched volunteers with similar axial length were selected as Group 3. All of the patients underwent optical coherence tomography angiography, and 3 mm × 3 mm scanning mode was chosen for analyzing vascular density and morphological characteristics on the choriocapillaris layer. In addition, Humphrey visual field 10–2 was evaluated in each subject. Results: The temporal deep vascular density was measured as 48.13% ± 8.5% in Group 1, 54.42% ± 10.3% in Group 2, and 60.35% ± 13.1% in Group 3. Deep temporal and deep hemi-inferior vascular density was significantly lower in Group 1 in comparison with Group 3 (p = 0.041 and p = 0.046, respectively). Visual field testing was normal in all patients. Conclusion: The optical coherence tomography angiography findings showed that the parafoveal deep temporal and deep hemi-inferior vascular plexus density was reduced in patients taking hydroxychloroquine for more than 5 years despite having normal perimetry. This observation, which can be obtained only through optical coherence tomography angiography, may be relevant to the early findings of hydroxychloroquine toxicity.


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