scholarly journals Novel Discoveries of Anterior Segment Parameters in Fellow Eyes of Acute Primary Angle Closure and Chronic Primary Angle Closure Glaucoma

2021 ◽  
Vol 62 (14) ◽  
pp. 6
Author(s):  
Shuqi You ◽  
Zhiqiao Liang ◽  
Kangyi Yang ◽  
Yu Zhang ◽  
Julius Oatts ◽  
...  
Keyword(s):  
Anterior Segment ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Acute Primary Angle Closure ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Anterior Segment Parameters ◽  
Fellow Eyes

scholarly journals Association of peripheral anterior synechiae with anterior segment parameters in eyes with primary angle closure glaucoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Yunhua Loo ◽  
Tin A. Tun ◽  
Eranga N. Vithana ◽  
Shamira A. Perera ◽  
Rahat Husain ◽  
...  
Keyword(s):  
Severe Disease ◽  
Anterior Segment ◽  
Anterior Chamber Depth ◽  
Multivariate Logistic Regression Analysis ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Mean Deviation ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Anterior Segment Parameters

AbstractTo investigate the association of peripheral anterior synechiae (PAS) with intraocular pressure (IOP) and anterior-segment parameters in subjects with primary angle-closure glaucoma (PACG). A total of 267 subjects with PACG were recruited and underwent gonioscopy and anterior-segment optical coherence tomography (ASOCT). Customized software was used to measure ASOCT parameters, including angle opening distance (AOD750) and trabecular-iris-space-area (TISA750) at 750 µm from the scleral spur, anterior chamber depth, width, area and volume (ACD, ACW, ACA, ACV), iris thickness (IT750), iris area (IAREA), and lens vault (LV). Presenting IOP was defined as the first IOP reading before the initiation of IOP-lowering treatment. The mean age of the 267 subjects was 67.0 ± 8.9 years, 140 (52.4%) were male, and 246 (92.1%) were of Chinese ethnicity. PAS was present in 122 (45.7%) subjects, and was most frequently found in the superior quadrant (79.5%). Subjects with PAS had greater presenting IOP (28.7 ± 12.9 vs 22.4 ± 9.7 mmHg, p < 0.001), narrower AOD750 (p < 0.001), smaller TISA750 (p < 0.001), ACD (p = 0.04), ACA (p = 0.02), ACV (p = 0.01) and larger LV (p = 0.01) compared to PACG eyes without PAS. No significant differences were noted for iris parameters. A multivariate logistic regression analysis showed that higher presenting IOP (β = 0.20, p < 0.001), worse visual field mean deviation (β = − 0.20, p = 0.01) and narrower AOD750 (β = − 0.25, p = 0.03) were the only parameters that significantly correlated with the extent of PAS in clock hours. Almost one-half of the subjects with PACG demonstrated PAS; these eyes were associated with higher presenting IOP, smaller anterior segment dimensions and more severe disease.

scholarly journals Associations Between the Choroidal Vascularity Index and Malignant Glaucoma After Trabeculectomy for Primary Angle Closure Glaucoma

2021 ◽  
Vol 8 ◽  
Author(s):  
Chengguo Zuo ◽  
Dingqiao Wang ◽  
Xinxing Guo ◽  
Hui Xiao ◽  
Shaoyang Zheng ◽  
...  
Keyword(s):  
Characteristic Curve ◽  
Angle Closure Glaucoma ◽  
Angle Closure ◽  
Primary Angle Closure ◽  
Primary Angle Closure Glaucoma ◽  
Malignant Glaucoma ◽  
Choroidal Vasculature ◽  
Control Study ◽  
Fellow Eyes ◽  
Sd Oct

Purpose: To compare the choroidal vasculature characteristics by using the choroidal vascularity index (CVI) in eyes with malignant glaucoma (MG), fellow eyes with non-MG, and eyes with uncomplicated primary angle-closure glaucoma (PACG) after trabeculectomy by spectral-domain optical coherence tomography (SD-OCT).Methods: This case–control study included 53 patients diagnosed with MG after trabeculectomy. Eyes with MG (n = 53) and the fellow eyes with non-MG (n = 50) were included. Eyes with PACG without MG after trabeculectomy (n = 60) were also enrolled as controls. The choroidal parameters, including CVI and the subfoveal choroidal thickness (SFCT), were measured by using SD-OCT images.Results: Eyes with MG and the fellow eyes showed a significantly lower CVI than eyes with PACG controls (p &lt; 0.001). After adjusting for age, sex, axial length (AL), and intraocular pressure (IOP), eyes with the greater CVI [odds ratio (OR), 0.44] were significantly related to MG. The area under the receiver operating characteristic curve of the CVI was greater than that of the SFCT in the diagnosis of MG (0.911 vs. 0.840, p = 0.034).Conclusion: Eyes with MG showed a significantly lower macular CVI than eyes with PACG controls. A higher macular CVI was an associated factor of eyes with MG. The CVI serves as a more stable and sensitive indicator for MG than the SFCT in this group of patients with PACG.

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