scholarly journals ERG Responses in Mice with Deletion of the Synaptic Ribbon Component RIBEYE

2020 ◽  
Vol 61 (5) ◽  
pp. 37
Author(s):  
Richard Fairless ◽  
Sarah K. Williams ◽  
Rashmi Katiyar ◽  
Stephan Maxeiner ◽  
Frank Schmitz ◽  
...  
Keyword(s):  
Synaptic Ribbon

Morphometry of Pineal Synaptic Ribbon Profile Numbers after Cytochalasin D Treatment1

1996 ◽  
Vol 156 (2) ◽  
pp. 94-98 ◽  
Author(s):  
E. Peschke ◽  
R. Spessert ◽  
I. Spiwoks-Becker ◽  
P. Dorner ◽  
L. Vollrath
Keyword(s):  
Cytochalasin D ◽  
Synaptic Ribbon

Tridimensional study of an anomalous synaptic ribbon in human retina

1969 ◽  
Vol 26 (5-6) ◽  
pp. 391-398 ◽  
Author(s):  
Robert Y. Foos ◽  
Walter Miyamasu ◽  
Eichi Yamada
Keyword(s):  
Human Retina ◽  
Synaptic Ribbon

scholarly journals Nanoscale dynamics of synaptic vesicle trafficking and fusion at the presynaptic active zone

eLife ◽  
2016 ◽  
Vol 5 ◽  
Author(s):  
Thirumalini Vaithianathan ◽  
Diane Henry ◽  
Wendy Akmentin ◽  
Gary Matthews
Keyword(s):  
Active Zone ◽  
Synaptic Vesicles ◽  
Super Resolution ◽  
Visual Signals ◽  
Dual Function ◽  
Macromolecular Complex ◽  
Synaptic Ribbon ◽  
Modes Of Transmission ◽  
Resolution Imaging ◽  
Specialized Structure

The cytomatrix at the active zone (CAZ) is a macromolecular complex that facilitates the supply of release-ready synaptic vesicles to support neurotransmitter release at synapses. To reveal the dynamics of this supply process in living synapses, we used super-resolution imaging to track single vesicles at voltage-clamped presynaptic terminals of retinal bipolar neurons, whose CAZ contains a specialized structure—the synaptic ribbon—that supports both fast, transient and slow, sustained modes of transmission. We find that the synaptic ribbon serves a dual function as a conduit for diffusion of synaptic vesicles and a platform for vesicles to fuse distal to the plasma membrane itself, via compound fusion. The combination of these functions allows the ribbon-type CAZ to achieve the continuous transmitter release required by synapses of neurons that carry tonic, graded visual signals in the retina.

Constancy of synaptic ribbon numbers in the retina of the arctic chary, Salvelinus alpinus

1990 ◽  
Vol 27 (2) ◽  
pp. 131-137 ◽  
Author(s):  
Sarah Perreault ◽  
M. Ather Ali ◽  
Sk�li Sk�lason ◽  
David L. G. Noakes
Keyword(s):  
Salvelinus Alpinus ◽  
The Arctic ◽  
Synaptic Ribbon

scholarly journals Synaptic ribbon formation during Xenopus inner ear organogenesis

2006 ◽  
Vol 295 (1) ◽  
pp. 457
Author(s):  
Marti M. Morales ◽  
Elba E. Serrano
Keyword(s):  
Inner Ear ◽  
Synaptic Ribbon

Quantitative aspects of synaptic ribbon formation in the outer plexiform layer of the developing cat retina

1989 ◽  
Vol 3 (1) ◽  
pp. 21-32 ◽  
Author(s):  
David H. Rapaport
Keyword(s):  
Electron Microscopy ◽  
Plexiform Layer ◽  
Outer Plexiform Layer ◽  
Synaptic Ribbons ◽  
Cone Photoreceptor ◽  
Synaptic Ribbon ◽  
Quantitative Electron Microscopy ◽  
Cat Retina ◽  
Area Centralis

AbstractThe development of synaptic ribbons in rod and cone photoreceptor terminals of the cat retina was studied using quantitative electron microscopy. At the region of the area centralis, synaptic ribbon profiles are initially recognized at PCD (postconception day) 59. Synaptic ribbon density increases rapidly, reaching a peak of 0.55 ribbons/μm3 at PCD 68 (postnatal day 3) and maintains approximately that value for an additional 8 d. Following PCD 76, ribbon density begins to decrease, to 0.37 ribbons/μm3 at PCD 82 and 0.25 ribbons/μm3 at PCD 102. Although ribbon density drops by approximately 50% during this 39-d period, the outer plexiform layer (OPL) volume at the area centralis increases by about 20%. Ribbon density continues to decrease gradually over a protracted period to reach a final adult value of 0.11–0.14 ribbons/μm3. During the period of high ribbon density, rod spherules with two, or even three ribbon profiles, were routinely observed. In contrast, in the adult, spherules with more than one ribbon profile are only rarely encountered. During development, the length of synaptic ribbon profiles increases from a mean of 0.22 μm at PCD 62 to the 0.47 μm mean length found in the adult.

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