scholarly journals Dynamic Changes of Retinal Microaneurysms in Diabetes Imaged With In Vivo Adaptive Optics Optical Coherence Tomography

2018 ◽  
Vol 59 (15) ◽  
pp. 5932 ◽  
Author(s):  
Julia Hafner ◽  
Matthias Salas ◽  
Christoph Scholda ◽  
Wolf-Dieter Vogl ◽  
Wolfgang Drexler ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Adaptive Optics ◽  
Optical Coherence ◽  
Dynamic Changes ◽  
Retinal Microaneurysms

scholarly journals Ultra-high resolution adaptive optics: optical coherence tomography for in vivo imaging of healthy and diseased retinal structures

2008 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Yan Zhang ◽  
Steven M. Jones ◽  
Stacey S. Choi ◽  
Barry Cense ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Optical Coherence

Adaptive optics - optical coherence tomography for in vivo retinal imaging: effects of spectral bandwidth on image quality

2006 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Steven M. Jones ◽  
Mingtao Zhao ◽  
Stacey S. Choi ◽  
Sophie S. Laut ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Image Quality ◽  
Adaptive Optics ◽  
Retinal Imaging ◽  
Optical Coherence ◽  
Spectral Bandwidth

scholarly journals Adaptive-optics optical coherence tomography for high-resolution and high-speed 3D retinal in vivo imaging

2005 ◽  
Vol 13 (21) ◽  
pp. 8532 ◽  
Author(s):  
Robert J. Zawadzki ◽  
Steven M. Jones ◽  
Scot S. Olivier ◽  
Mingtao Zhao ◽  
Bradley A. Bower ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
High Resolution ◽  
Adaptive Optics ◽  
In Vivo Imaging ◽  
High Speed ◽  
Optical Coherence

scholarly journals In vivo imaging of human photoreceptor mosaic with wavefront sensorless adaptive optics optical coherence tomography

2015 ◽  
Vol 6 (2) ◽  
pp. 580 ◽  
Author(s):  
Kevin S. K. Wong ◽  
Yifan Jian ◽  
Michelle Cua ◽  
Stefano Bonora ◽  
Robert J. Zawadzki ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Adaptive Optics ◽  
In Vivo Imaging ◽  
Optical Coherence ◽  
Photoreceptor Mosaic

scholarly journals In vivoimaging of coral tissue and skeleton with optical coherence tomography

2016 ◽  
Author(s):  
Daniel Wangpraseurt ◽  
Camilla Wentzel ◽  
Steven L. Jacques ◽  
Michael Wagner ◽  
Michael Kuhl
Keyword(s):  
Optical Coherence Tomography ◽  
Surface Area ◽  
Fluorescent Protein ◽  
Coral Tissue ◽  
Optical Coherence ◽  
Pocillopora Damicornis ◽  
Dynamic Changes ◽  
Linear Contraction ◽  
Non Invasive

AbstractOptical coherence tomography (OCT) is a non-invasive three-dimensional imaging technique with micrometer resolution allowing microstructural characterization of tissuesin vivoand in real time. We present the first application of OCT forin vivoimaging of tissue and skeleton structure of intact living corals spanning a variety of morphologies and tissue thickness. OCT visualized different coral tissue layers (e.g. endoderm vs ectoderm), special structures such as mesenterial filaments and skeletal cavities, as well as mucus release from living corals. We also developed a new approach for non-invasive imaging and quantification of chromatophores containing green fluorescent protein (GFP)-like host pigment granules in coral tissue. The chromatophore system is hyper-reflective and can thus be imaged with good optical contrast in OCT, enabling quantification of chromatophore size, distribution and abundance. Because of its rapid imaging speed, OCT can also be used to quantify coral tissue movement showing that maximal linear contraction velocity was ~120 μm per second upon high light stimulation. Based on OCT imaging of tissue expansion and contraction, we made first estimates of dynamic changes in the coral tissue surface area, which varied by a factor of 2 between the contracted and expanded state of the coralPocillopora damicornis. We conclude that OCT is an excellent novel tool forin vivotomographic imaging of corals that can reveal tissue and skeleton organization as well as quantify dynamic changes in tissue structure and coral surface area non-invasively and at high spatio-temporal resolution.

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