scholarly journals A Histologic Categorization of Aqueous Outflow Routes in Familial Open-Angle Glaucoma and Associations With Mutations in the MYOC Gene in Japanese Patients

2017 ◽  
Vol 58 (5) ◽  
pp. 2818 ◽  
Author(s):  
Teruhiko Hamanaka ◽  
Masae Kimura ◽  
Tetsuro Sakurai ◽  
Nobuo Ishida ◽  
Jun Yasuda ◽  
...  
Keyword(s):  
Open Angle Glaucoma ◽  
Japanese Patients ◽  
Open Angle ◽  
Aqueous Outflow

scholarly journals High frequency of open-angle glaucoma in Japanese patients with Alzheimer's disease

2006 ◽  
Vol 246 (1-2) ◽  
pp. 79-83 ◽  
Author(s):  
Hiroki Tamura ◽  
Hideshi Kawakami ◽  
Takashi Kanamoto ◽  
Tomoko Kato ◽  
Tomoko Yokoyama ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
High Frequency ◽  
Open Angle Glaucoma ◽  
Japanese Patients ◽  
Open Angle

scholarly journals Safety and Efficacy of Two Trabecular Micro-Bypass Stents as the Sole Procedure in Japanese Patients with Medically Uncontrolled Primary Open-Angle Glaucoma: A Pilot Case Series

2017 ◽  
Vol 2017 ◽  
pp. 1-6 ◽  
Author(s):  
Daisuke Shiba ◽  
Shingo Hosoda ◽  
Saori Yaguchi ◽  
Naoki Ozeki ◽  
Kenya Yuki ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Case Series ◽  
Japanese Patients ◽  
Early Postoperative Period ◽  
Open Angle ◽  
Corrected Visual Acuity ◽  
Stent System ◽  
Registration Number ◽  
Favorable Safety

Purpose. To evaluate efficacy and safety of a trabecular micro-bypass stent system when used as the sole procedure in Japanese patients with medically uncontrolled primary open-angle glaucoma (POAG). Design. Prospective nonrandomized interventional pilot study. Methods. Ten eyes of 10 Japanese patients with medically uncontrolled POAG taking three ocular hypotensive medications were treated using only the implantation of two iStent trabecular micro-bypass stents. Each patient continued to take the same ocular hypotensive medications used preoperatively throughout the study. Intraocular pressure (IOP) and endothelial cell density (ECD) were determined at baseline and at 1, 3, and 6 months postoperatively. Best-corrected visual acuity (BCVA) was measured at baseline and 6 months after surgery. Results. Mean IOP was 22.0±3.0 mmHg at baseline and 16.9±3.6 mmHg at 6 months, which represented a mean reduction of 5.1 mmHg or 23.2%. No significant changes were observed in the ECD and BCVA. Complications that occurred during the early postoperative period included hyphema, peripheral anterior synechiae, and occlusion of the stent by the iris. Conclusion. Implantation of two trabecular micro-bypass stents as the sole procedure in Japanese POAG patients effectively reduced IOP and exhibited a favorable safety profile. Clinical Trials Registration number is UMIN000004002.

Mutations in the optineurin gene in Japanese patients with primary open-angle glaucoma and normal tension glaucoma

2004 ◽  
Vol 125A (1) ◽  
pp. 1-4 ◽  
Author(s):  
Yoshiki Toda ◽  
Sa Tang ◽  
Kenji Kashiwagi ◽  
Fumihiko Mabuchi ◽  
Hiroyuki Iijima ◽  
...  
Keyword(s):  
Primary Open Angle Glaucoma ◽  
Open Angle Glaucoma ◽  
Japanese Patients ◽  
Normal Tension Glaucoma ◽  
Open Angle

SNPs and Interaction Analyses of Noelin 2, Myocilin, and Optineurin Genes in Japanese Patients with Open-Angle Glaucoma

2006 ◽  
Vol 47 (12) ◽  
pp. 5368 ◽  
Author(s):  
Tomoyo Funayama ◽  
Yukihiko Mashima ◽  
Yuichiro Ohtake ◽  
Karin Ishikawa ◽  
Nobuo Fuse ◽  
...  
Keyword(s):  
Open Angle Glaucoma ◽  
Japanese Patients ◽  
Open Angle
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