scholarly journals Spatial Correspondence Between Intraretinal Fluid, Subretinal Fluid, and Pigment Epithelial Detachment in Neovascular Age-Related Macular Degeneration

2017 ◽  
Vol 58 (10) ◽  
pp. 4039 ◽  
Author(s):  
Sophie Klimscha ◽  
Sebastian M. Waldstein ◽  
Thomas Schlegl ◽  
Hrvoje Bogunovic ◽  
Amir Sadeghipour ◽  
...  
2019 ◽  
Vol 4 (4) ◽  
pp. 327-331
Author(s):  
James H. Powers ◽  
C. Ellis Wisely ◽  
Ananth Sastry ◽  
Sharon Fekrat

Purpose: This report discusses a case of neovascular age-related macular degeneration with mixed serous pigment epithelial detachment (PED) that was unresponsive to antivascular endothelial growth injections but responded to the addition of intravitreal steroid injection. Methods: We report a case. Results: A 75-year-old woman with neovascular age-related macular degeneration developed a mixed serous PED in her right eye. Three monthly aflibercept (Eylea, Regeneron) treatments led to resolution of associated intraretinal fluid; however, the mixed serous and fibrovascular PED significantly increased in size. The addition of intravitreal dexamethasone (Ozurdex, Allergan) to monthly aflibercept led to prompt flattening of the PED. Three months later, the PED recurred despite continued administration of monthly aflibercept. Conclusions: This case supports a growing body of research that PEDs unresponsive to antivascular endothelial growth injections may respond to intravitreal steroid injections.


2012 ◽  
Vol 228 (2) ◽  
pp. 102-109 ◽  
Author(s):  
Takayuki Baba ◽  
Masayasu Kitahashi ◽  
Mariko Kubota-Taniai ◽  
Toshiyuki Oshitari ◽  
Shuichi Yamamoto

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