scholarly journals Ocular Perfusion Pressure and Choroidal Thickness in Early Age-Related Macular Degeneration Patients With Reticular Pseudodrusen

2016 ◽  
Vol 57 (15) ◽  
pp. 6604 ◽  
Author(s):  
Cheolmin Yun ◽  
Jaemoon Ahn ◽  
Minjung Kim ◽  
Soon-Young Hwang ◽  
Seong-Woo Kim ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Perfusion Pressure ◽  
Age Related Macular Degeneration ◽  
Early Age ◽  
Ocular Perfusion Pressure ◽  
Reticular Pseudodrusen ◽  
Ocular Perfusion ◽  
Age Related

scholarly journals Association between axial length and choroidal thickness in early age-related macular degeneration

PLoS ONE ◽  
2020 ◽  
Vol 15 (10) ◽  
pp. e0240357
Author(s):  
Maho Sato ◽  
Sakiko Minami ◽  
Norihiro Nagai ◽  
Misa Suzuki ◽  
Toshihide Kurihara ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Early Age ◽  
Age Related

Choroidal changes in intermediate age-related macular degeneration patients with drusen or pseudodrusen

2020 ◽  
pp. 112067212091453 ◽  
Author(s):  
Raffaella Rosa ◽  
Paolo Corazza ◽  
Maria Musolino ◽  
Chiara Mochi ◽  
Guido Maiello ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Flow Area ◽  
Swept Source ◽  
Reticular Pseudodrusen ◽  
Vascular Flow ◽  
Age Related

Reticular pseudodrusen are associated with a thinner choroid. The aim of our study was to determine the differences in central choroidal thickness and choriocapillaris vascular flow area between eyes with and without reticular pseudodrusen using swept-source optical coherence tomography and swept-source optical coherence tomography angiography. We conducted a retrospective case control study which included 27 eyes from 27 consecutive patients with intermediate age-related macular degeneration and 17 eyes from 17 healthy participants. Complete ophthalmic examinations were carried out including axial length measurements; fundus color retinography; fundus autofluorescence; swept-source optical coherence tomography and swept-source optical coherence tomography angiography; central choroidal thickness and choriocapillaris vascular flow area. Patients were classified as no reticular pseudodrusen, mild reticular pseudodrusen, and severe reticular pseudodrusen. Mean central choroidal thickness in patients exhibiting severe reticular pseudodrusen (110 ± 56 μm) was significantly smaller than in patients with no reticular pseudodrusen (201 ± 76 μm, p < 0.01). Mean choriocapillaris vascular flow area in severe reticular pseudodrusen patients (45.2% ± 3.0%) was also significantly less than in patients with no (47.9% ± 1.6%, p < 0.001) and mild reticular pseudodrusen (47.7% ± 1.0%, p < 0.05). Stepwise multiple regression models confirmed the association of reticular pseudodrusen with central choroidal thickness (p < 0.001) and choriocapillaris vascular flow area (p < 0.01) even after accounting for age, axial length, and refractive error. Soft drusen were not associated with changes in either central choroidal thickness (p = 0.13) nor choriocapillaris vascular flow area (p = 0.29). A significant, positive relationship was found between central choroidal thickness and choriocapillaris vascular flow area (r = 0.44, p = 0.01). Therefore, both central choroidal thickness and choriocapillaris vascular flow area are decreased in eyes with reticular pseudodrusen, as compared to healthy eyes and intermediate age-related macular degeneration eyes not exhibiting reticular pseudodrusen. In addition, central choroidal thickness and choriocapillaris vascular flow area are related, and the reduction of either is directly associated to the severity of reticular pseudodrusen. Further studies are needed to assess the clinical significance of these findings.

scholarly journals Relationship between reticular pseudodrusen and choroidal thickness in intermediate age-related macular degeneration

2018 ◽  
Vol 46 (5) ◽  
pp. 485-494 ◽  
Author(s):  
Chi YD Ho ◽  
Jia J Lek ◽  
Khin Z Aung ◽  
Myra B McGuinness ◽  
Chi D Luu ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Reticular Pseudodrusen ◽  
Age Related

Association Between Subfoveal Choroidal Thickness, Reticular Pseudodrusen, and Geographic Atrophy in Age-Related Macular Degeneration

2015 ◽  
Vol 46 (5) ◽  
pp. 513-521 ◽  
Author(s):  
Mariana R. Thorell ◽  
Raquel Goldhardt ◽  
Renata Portella Nunes ◽  
Carlos Alexandre de Amorim Garcia Filho ◽  
Ashkan M. Abbey ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Subfoveal Choroidal Thickness ◽  
Reticular Pseudodrusen ◽  
Age Related

scholarly journals Retinal and Choroidal Thickness in Early Age-Related Macular Degeneration

2011 ◽  
Vol 152 (6) ◽  
pp. 1030-1038.e2 ◽  
Author(s):  
Ashley Wood ◽  
Alison Binns ◽  
Tom Margrain ◽  
Wolfgang Drexler ◽  
Boris Považay ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Early Age ◽  
Age Related
Sign in / Sign up

Export Citation Format

Share Document