scholarly journals Estimating Mean Ocular Perfusion Pressure Using Mean Arterial Pressure and Intraocular Pressure

2016 ◽  
Vol 57 (4) ◽  
pp. 2260 ◽  
Author(s):  
Karel Van Keer ◽  
João Barbosa Breda ◽  
Luís Abegão Pinto ◽  
Ingeborg Stalmans ◽  
Evelien Vandewalle
2001 ◽  
Vol 95 (6) ◽  
pp. 1351-1355 ◽  
Author(s):  
Mary Ann Cheng ◽  
Alexandre Todorov ◽  
René Tempelhoff ◽  
Tom McHugh ◽  
C. Michael Crowder ◽  
...  

Background Ocular perfusion pressure is commonly defined as mean arterial pressure minus intraocular pressure (IOP). Changes in mean arterial pressure or IOP can affect ocular perfusion pressure. IOP has not been studied in this context in the prone anesthetized patient. Methods After institutional human studies committee approval and informed consent, 20 patients (American Society of Anesthesiologists physical status I-III) without eye disease who were scheduled for spine surgery in the prone position were enrolled. IOP was measured with a Tono-pen XL handheld tonometer at five time points: awake supine (baseline), anesthetized (supine 1), anesthetized prone (prone 1), anesthetized prone at conclusion of case (prone 2), and anesthetized supine before wake-up (supine 2). Anesthetic protocol was standardized. The head was positioned with a pinned head-holder. Data were analyzed with repeated-measures analysis of variance and paired t test. Results Supine 1 IOP (13 +/- 1 mmHg) decreased from baseline (19 +/- 1 mmHg) (P < 0.05). Prone 1 IOP (27 +/- 2 mmHg) increased in comparison with baseline (P < 0.05) and supine 1 (P < 0.05). Prone 2 IOP (40 +/- 2 mmHg) was measured after 320 +/- 107 min in the prone position and was significantly increased in comparison with all previous measurements (P < 0.05). Supine 2 IOP (31 +/- 2 mmHg) decreased in comparison with prone 2 IOP (P < 0.05) but was relatively elevated in comparison with supine 1 and baseline (P < 0.05). Hemodynamic and ventilatory parameters remained unchanged during the prone period. Conclusions Prone positioning increases IOP during anesthesia. Ocular perfusion pressure could therefore decrease, despite maintenance of normotension.


Author(s):  
S. Shruthi

Aim: To describe the distribution of ocular perfusion pressure hypertensive patients. Design: Cross-sectional observation study. Materials and Methods: Hospital-based, case control cross-sectional study conducted on 100 patients. Systolic and diastolic blood pressure (SBP and DBP) was measured with a Mercury Sphygmomanometer. Mean ocular perfusion pressure (MOPP) = ⅔ (mean arterial pressure − IOP), where mean arterial pressure (MAP) = DBP + ⅓ (SBP − DBP), systolic perfusion pressure (SPP) = SBP – IOP and diastolic perfusion pressure (DPP) = DBP − IOP was calculated. Results: High values of diastolic BP (>90 mmHg) and low values of OPP (<40 mmHg) were associated to an increased risk of confirmed POAG. Conclusion: There is a close relationship between OPP and confirmed glaucoma in hypertensive patients.


2018 ◽  
Vol 59 (11) ◽  
pp. 4496 ◽  
Author(s):  
John E. Markert ◽  
Jessica V. Jasien ◽  
Daniel C. Turner ◽  
Carrie Huisingh ◽  
Christopher A. Girkin ◽  
...  

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Izakson Alexander ◽  
Sindawi Ahmad ◽  
Ben Shachar Inbar ◽  
Pikkel Joseph

Purpose. Visual loss is a devastating perioperative complication that can result from elevated intraocular pressure (IOP). The Trendelenburg position during surgery increases IOP. The purpose of this study was to quantify IOP changes in patients undergoing laparoscopic hysterectomy, at different time points and body positions throughout the procedure, and to compare fluctuations of IOP during the perioperative period according to two fluid management protocols.Methods. Thirty women scheduled to undergo elective gynecologic laparoscopic pelvic surgery were randomly allocated to receive a liberal or restrictive fluid management protocol. IOP, mean arterial pressure, heart rate, exhaled tidal volume, end-tidal CO2, and ocular perfusion pressure were assessed prior, during, and postsurgery, at 8 time points altogether.Results. Mean changes in IOP were similar for the two protocols; the peak IOP was at the steep (peak) Trendelenburg position. For each protocol, IOP correlated positively with mean arterial pressure, and mean blood pressure correlated with ocular perfusion pressure.Conclusion. IOP was elevated during laparoscopic pelvic surgery and particularly at the steep Trendelenburg position. No differences were found in any of the parameters examined according to a liberal or restrictive fluid management protocol.


2018 ◽  
pp. 15-18

Background: Glaucoma is a frequent leading cause of blindness. Objective evidence showed that it can be secondary to optic nerve head hypoperfusion and autonomic dysfunction, not only to ocular hypertension. This makes the assessment of ocular blood flow a crucial step in the management of this disease. Aim: To investigate the circadian fluctuations of the intraocular pressure (IOP) and of the mean ocular perfusion pressure (mOPP) in patients with different types of glaucoma. Materials and methods: Sixty-five eyes of 65 glaucoma patients, managed in the Ophthalmology Department of the Careggi University Hospital, Firenze, Italy (2012-2014). Among these eyes, 22 had normotensive glaucoma (NTG), 21 hypertensive glaucoma (HTG), and 22 exfoliative glaucoma (XTG). The IOP was measured by Goldmann tonometry and the blood pressure, both systolic (sBP) and diastolic (dBP), by Riva-Rocci sphygmomanometry, at three time points (8am, 2pm, 8pm). The mOPP was then calculated according to the formula mOPP = [2/3 (2/3 dBP + 1/3sBP) - IOP]. Results: The fluctuations of IOP and mOPP were statistically significant in all the studied eyes (p<0.001 for all the comparisons). Both IOP and mOPP showed significantly larger fluctuations in the XFG eyes than in the NTG and HTG ones (p<0.001 for IOP and p=0.001 for mOPP). Conclusions: In our study, the mOPP had larger circadian fluctuations in eyes with XFG than in those with NTG and HTG. This parameter deserves to be assessed in all types of glaucoma. Key words: Glaucoma, intraocular pressure, mean ocular perfusion pressure.


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