scholarly journals Anatomical and Gene Expression Changes in the Retinal Pigmented Epithelium Atrophy 1 (rpea1) Mouse: A Potential Model of Serous Retinal Detachment

2016 ◽  
Vol 57 (11) ◽  
pp. 4641 ◽  
Author(s):  
Gabriel Luna ◽  
Geoffrey P. Lewis ◽  
Kenneth A. Linberg ◽  
Bo Chang ◽  
Quiri Hu ◽  
...  
Keyword(s):  
Gene Expression ◽  
Retinal Detachment ◽  
Potential Model ◽  
Serous Retinal Detachment ◽  
Retinal Pigmented Epithelium ◽  
Pigmented Epithelium

scholarly journals Uveal Melanoma and Secondary Angle-Closure Crisis: A Case Report and Literature Review

2021 ◽  
pp. 476-480
Author(s):  
Tung Thanh Hoang ◽  
Tuan Anh Hoang ◽  
Peter McCluskey ◽  
John Grigg
Keyword(s):  
Retinal Detachment ◽  
Uveal Melanoma ◽  
Vision Loss ◽  
Serous Retinal Detachment ◽  
Anterior Segment ◽  
Angle Closure ◽  
Large Tumor ◽  
Tumor Mass ◽  
Healthy Female ◽  
Life Threatening

A 66-years-old Vietnamese healthy female patient presented with prolonged severe right ocular pain and complete vision loss in that eye. Anterior segment assessment including gonioscopy identified angle-closure configuration. A suspected ciliary body melanoma was seen through the pupil. Posterior segment examination revealed a large tumor mass and 360° retinal detachment (kissing configuration). An ultrasound examination was consistent with a uveal tumor. The painful, blind right eye with a tumor mass was enucleated. Histopathology confirmed a type A uveal spindle cell melanoma associated with total serous retinal detachment without evidence of tumor necrosis, epithelioid cells, scleral, or optic nerve infiltration. There was no evidence of metastasis after 1-year of follow-up. It is critically important to differentiate primary and secondary angle closure, especially in cases with life-threatening ocular malignancy as uveal melanoma.

scholarly journals A Case Of Ipilimumab-Induced Unusual Serous Retinal Detachment In Bilateral Eyes

2019 ◽  
Vol Volume 12 ◽  
pp. 355-361 ◽  
Author(s):  
Tomoko Miyakubo ◽  
Ryo Mukai ◽  
Kosuke Nakamura ◽  
Hidetaka Matsumoto ◽  
Hideo Akiyama
Keyword(s):  
Retinal Detachment ◽  
Serous Retinal Detachment

scholarly journals Risk of serous retinal detachment in patients with end-stage renal disease on dialysis

PLoS ONE ◽  
2017 ◽  
Vol 12 (6) ◽  
pp. e0180133 ◽  
Author(s):  
Yuh-Shin Chang ◽  
Shih-Feng Weng ◽  
Chun Chang ◽  
Jhi-Joung Wang ◽  
Hong-I Chen ◽  
...  
Keyword(s):  
Retinal Detachment ◽  
Renal Disease ◽  
End Stage Renal Disease ◽  
Serous Retinal Detachment ◽  
Stage Renal Disease ◽  
End Stage

scholarly journals EFFECTS OF CYCLIC AMP AND SEPHADEX FRACTIONS OF CHICK EMBRYO EXTRACT ON CLONED RETINAL PIGMENTED EPITHELIUM IN TISSUE CULTURE

1974 ◽  
Vol 61 (2) ◽  
pp. 369-382 ◽  
Author(s):  
D. A. Newsome ◽  
R. T. Fletcher ◽  
W. G. Robison ◽  
K. R. Kenyon ◽  
G. J. Chader
Keyword(s):  
Molecular Weight ◽  
Chick Embryo ◽  
Adenosine Monophosphate ◽  
Cell Number ◽  
Retinal Pigmented Epithelium ◽  
Culture Dish ◽  
Adhesive Properties ◽  
Embryo Extract ◽  
Chick Embryo Extract ◽  
Pigmented Epithelium

The effects of dibutyryl cyclic 3',5'-adenosine monophosphate (BcAMP) and Sephadex G-25 fractions of chick embryo extract on the growth rate, morphology, and pigmentation of normal chick retinal pigmented epithelium (PE) were investigated. Seven cloned PE cell lines were each grown in modified Ham's F-12 medium alone (F-12), or in F-12 supplemented with either high molecular weight (H) or low molecular weight (L) fractions of chick embryo extract. Cells grown in F-12 alone or in L medium formed compact epithelial sheets, whereas cells grown in H had a fibrocytic appearance and formed poorly organized monolayers. In H plus BcAMP, cell morphology was more epithelioid than in H alone, and generally the monolayers appeared more differentiated. Under each of these three culture conditions, 2 x 10-4 M BCAMP retarded the increase in cell number and decreased the final number of cells per culture dish, but had little effect on plating efficiency. BcAMP also increased the rate of cell adhesion to a plastic substratum. Pigmentation was marked in cultures grown in F-12 or in L alone, but the addition of BcAMP dramatically reduced visible pigmentation. This effect was reversed when BcAMP was removed from the culture medium. Thus BcAMP modifies cell and colonial morphology, rate of cell accumulation, adhesive properties, and pigmentation of normal PE cells.

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