scholarly journals Optic Nerve Head Measurements With Optical Coherence Tomography: A Phantom-Based Study Reveals Differences Among Clinical Devices

2016 ◽  
Vol 57 (9) ◽  
pp. OCT413 ◽  
Author(s):  
Anant Agrawal ◽  
Jigesh Baxi ◽  
William Calhoun ◽  
Chieh-Li Chen ◽  
Hiroshi Ishikawa ◽  
...  
PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0180128 ◽  
Author(s):  
Tiago S. Prata ◽  
Flavio S. Lopes ◽  
Vitor G. Prado ◽  
Izabela Almeida ◽  
Igor Matsubara ◽  
...  

2009 ◽  
Vol 40 (3) ◽  
pp. 255-263 ◽  
Author(s):  
Yuriko Kotera ◽  
Yoshiaki Yasuno ◽  
Masanori Hangai ◽  
Ryo Inoue ◽  
Shuichi Makita ◽  
...  

2020 ◽  
Vol 29 (2) ◽  
pp. 131
Author(s):  
Melike BALIKOGLU ◽  
Erdinc AYDIN ◽  
Pinar NALCACIOGLU ◽  
Nur DOGANAY KUMCU ◽  
Seher SARITEPE IMREL ◽  
...  

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
Anita S. Y. Chan ◽  
Tin Aung Tun ◽  
John C. Allen ◽  
Myoe Naing Lynn ◽  
Sai Bo Bo Tun ◽  
...  

Abstract In humans, the longitudinal characterisation of early optic nerve head (ONH) damage in ocular hypertension (OHT) is difficult as patients with glaucoma usually have structural ONH damage at the time of diagnosis. Previous studies assessed glaucomatous ONH cupping by measuring the anterior lamina cribrosa depth (LCD) and minimal rim width (MRW) using optical coherence tomography (OCT). In this study, we induced OHT by repeated intracameral microbead injections in 16 cynomolgus primates (10 unilateral; 6 bilateral) and assessed the structural changes of the ONH longitudinally to observe early changes. Elevated intraocular pressure (IOP) in OHT eyes was maintained for 7 months and serial OCT measurements were performed during this period. The mean IOP was significantly elevated in OHT eyes when compared to baseline and compared to the control eyes. Thinner MRW and deeper LCD values from baseline were observed in OHT eyes with the greatest changes seen between month 1 and month 2 of OHT. Both the mean and maximum IOP values were significant predictors of MRW and LCD changes, although the maximum IOP was a slightly better predictor. We believe that this model could be useful to study IOP-induced early ONH structural damage which is important for understanding glaucoma pathogenesis.


Sign in / Sign up

Export Citation Format

Share Document