scholarly journals Early Corneal Cellular and Nerve Fiber Pathology in Young Patients With Type 1 Diabetes Mellitus Identified Using Corneal Confocal Microscopy

2016 ◽  
Vol 57 (3) ◽  
pp. 853 ◽  
Author(s):  
Eszter Szalai ◽  
Eszter Deák ◽  
László Módis ◽  
Gábor Németh ◽  
András Berta ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Confocal Microscopy ◽  
Type 1 Diabetes Mellitus ◽  
Nerve Fiber ◽  
Young Patients ◽  
Corneal Confocal Microscopy

scholarly journals Corneal Confocal Microscopy in Type 1 Diabetes Mellitus: A Six-Year Longitudinal Study

2022 ◽  
Vol 11 (1) ◽  
pp. 17
Author(s):  
Stuti L. Misra ◽  
James A. Slater ◽  
Charles N. J. McGhee ◽  
Monika Pradhan ◽  
Geoffrey D. Braatvedt
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Longitudinal Study ◽  
Confocal Microscopy ◽  
Type 1 Diabetes Mellitus ◽  
Corneal Confocal Microscopy

Corneal confocal microscopy identifies a reduction in corneal keratocyte density and sub-basal nerves in children with type 1 diabetes mellitus

2021 ◽  
pp. bjophthalmol-2021-319057
Author(s):  
Hoda Gad ◽  
Bara Al-Jarrah ◽  
Saras Saraswathi ◽  
Sara Mohamed ◽  
Alise Kalteniece ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Confocal Microscopy ◽  
Type 1 Diabetes Mellitus ◽  
Nerve Fibre ◽  
Healthy Controls ◽  
Corneal Confocal Microscopy ◽  
Corneal Nerve ◽  
Keratocyte Density

PurposeTo assess whether alterations in stromal keratocyte density are related to loss of corneal nerve fibres in children with type 1 diabetes mellitus (T1DM).MethodsTwenty participants with T1DM and 20 age-matched healthy controls underwent corneal confocal microscopy. Corneal sub-basal nerve morphology and corneal keratocyte density (KD) were quantified.ResultsCorneal nerve fibre density (CNFD) (p<0.001), corneal nerve branch density (p<0.001), corneal nerve fibre length (CNFL) (p<0.001) and inferior whorl length (IWL) (p<0.001) were lower in children with T1DM compared with healthy controls. Anterior (p<0.03) and mid (p=0.03) stromal KDs were lower with no difference in posterior KD (PKD) in children with T1DM compared with controls. Age, duration of diabetes, height, weight and body mass index did not correlate with anterior (AKD), mid (MKD) or PKD. Inverse correlations were found between glycated haemoglobin and PKD (r=−0.539, p=0.026), bilirubin with MKD (r=−0.540, p=0.025) and PKD (r=−0.531, p=0.028) and 25-hydroxycholecalciferol with MKD (r=−0.583, p=0.018). CNFD, CNFL and IWL did not correlate with AKD, MKD or PKD.ConclusionThis study demonstrates a reduction in corneal nerves and anterior and mid stromal KD in children with T1DM, but no correlation between corneal nerve and keratocyte cell loss.

MCP-1and IL-1β expression in the myocardia of two young patients with Type 1 diabetes mellitus and fatal diabetic ketoacidosis

2014 ◽  
Vol 96 (1) ◽  
pp. 71-79 ◽  
Author(s):  
Jianli Niu ◽  
M.G.F. Gilliland ◽  
Zhuqing Jin ◽  
Pappachan E. Kolattukudy ◽  
William H. Hoffman
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Diabetic Ketoacidosis ◽  
Young Patients

scholarly journals Skin microvascular circulation is not affected by diabetes duration in young patients with non-complicated type 1 diabetes mellitus

2019 ◽  
Vol 25 (4) ◽  
pp. 183-187
Author(s):  
Melanie Wielicka ◽  
Jolanta Neubauer-Geryk ◽  
Agnieszka Brandt-Varma ◽  
Małgorzata Myśliwiec ◽  
Leszek Bieniaszewski
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Type 1 Diabetes Mellitus ◽  
Young Patients ◽  
Diabetes Duration

scholarly journals NGAL and cystatin C: two possible early markers of diabetic nephropathy in young patients with type 1 diabetes mellitus: one year follow up

HORMONES ◽  
2014 ◽  
Author(s):  
Nektraria Papadopoulou-Marketou ◽  
Chrysanthi Skevaki ◽  
Ioanna Kosteria ◽  
Melpomeni Peppa ◽  
George Chrousos ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 1 Diabetes ◽  
Diabetic Nephropathy ◽  
Type 1 Diabetes Mellitus ◽  
Cystatin C ◽  
Young Patients ◽  
Early Markers ◽  
One Year
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