The Ability of SD-OCT to Differentiate Early Glaucoma With High Myopia From Highly Myopic Controls and Nonhighly Myopic Controls

2015 ◽  
Vol 56 (11) ◽  
pp. 6573 ◽  
Author(s):  
Azusa Akashi ◽  
Akiyasu Kanamori ◽  
Kaori Ueda ◽  
Yukako Inoue ◽  
Yuko Yamada ◽  
...  
Keyword(s):  
High Myopia ◽  
Early Glaucoma ◽  
Sd Oct

Peripapillary changes detected by SD OCT in eyes with high myopia

2012 ◽  
Vol 90 ◽  
pp. 0-0
Author(s):  
A CHEBIL ◽  
B BEN ACHOUR ◽  
M BOULADI ◽  
F KORT ◽  
F MGHAIETH ◽  
...  
Keyword(s):  
High Myopia ◽  
Sd Oct

Impact of high myopia on the performance of SD-OCT parameters to detect glaucoma

2012 ◽  
Vol 250 (12) ◽  
pp. 1843-1849 ◽  
Author(s):  
Takuhei Shoji ◽  
Yui Nagaoka ◽  
Hiroki Sato ◽  
Etsuo Chihara
Keyword(s):  
High Myopia ◽  
Sd Oct

Peripapillary Retinoschisis in High Myopia: A Novel Clinical Entity Revealed by SD-OCT

2011 ◽  
Vol 82 (6) ◽  
pp. 362
Author(s):  
Jerome Sherman ◽  
Samantha Slotnick ◽  
Richard Madonna ◽  
Sanjeev Nath ◽  
Raniah Hallal ◽  
...  
Keyword(s):  
High Myopia ◽  
Clinical Entity ◽  
Sd Oct

scholarly journals Detailed Distribution of Corneal Epithelial Thickness and Correlated Characteristics Measured with SD-OCT in Myopic Eyes

2017 ◽  
Vol 2017 ◽  
pp. 1-8
Author(s):  
Yanan Wu ◽  
Yan Wang
Keyword(s):  
Corneal Epithelium ◽  
High Myopia ◽  
Thickness Distribution ◽  
Corneal Thickness ◽  
Distribution Profile ◽  
Corneal Epithelial ◽  
Epithelial Thickness ◽  
Corneal Epithelial Thickness ◽  
Positive Correlations ◽  
Sd Oct

Purpose.To investigate the detailed distribution of corneal epithelial thickness in single sectors and its correlated characteristics in myopic eyes.Methods.SD-OCT was used to measure the corneal epithelial thickness distribution profile. Differences of corneal epithelial thickness between different parameters and some correlations of characteristics were calculated.Results.The thickest and thinnest part of epithelium were found at the nasal-inferior sector (P<0.05) and at the superior side (P<0.05), respectively. Subjects in the low and moderate myopia groups have thicker epithelial thickness than those in the high myopia group (P<0.05). Epithelial thickness was 1.39 μm thicker in male subjects than in female subjects (P<0.001). There was a slight negative correlation between corneal epithelial thickness and age (r=−0.13,P=0.042). Weak positive correlations were found between corneal epithelial thickness and corneal thickness (r=0.148,P=0.031). No correlations were found between corneal epithelial thickness, astigmatism axis, corneal front curvature, and IOP.Conclusions.The epithelial thickness is not evenly distributed across the cornea. The thickest location of the corneal epithelium is at the nasal-inferior sector. People with high myopia tend to have thinner corneal epithelium than low–moderate myopic patients. The corneal epithelial thickness is likely to be affected by some parameters, such as age, gender, and corneal thickness.

scholarly journals Focal Choroidal Elevations: Localized Pigment Epithelial Contour Alterations due to Isolated Choroidal Vessels

2019 ◽  
Vol 2019 ◽  
pp. 1-7
Author(s):  
Rachel L. Chu ◽  
Nicole A. Pannullo ◽  
Eric J. Sigler
Keyword(s):  
High Myopia ◽  
Case Series ◽  
Age Related Macular Degeneration ◽  
Enhanced Depth Imaging ◽  
Lumen Diameter ◽  
Imaging Features ◽  
Pigment Epithelial ◽  
Age Related ◽  
Choroidal Vessels ◽  
Sd Oct

Purpose. The objective of this case series was to describe the clinical and imaging features of focal choroidal elevations (FCE), which are chorioretinal contour changes induced by individual choroidal vessels within an overall thin-appearing choroid. Methods. A total of 787 enhanced depth imaging (EDI) spectral domain optical coherence tomography (SD-OCT) patient images were initially screened for the presence of FCE. Prospective imaging analysis of 38 patients with FCE was done. Mean central macular choroidal thickness (CMCT), FCE location, FCE vessel lumen diameter, patient demographics, cycloplegic autorefraction, ophthalmoscopic findings, and presence of choroidal neovascularization (CNV) in the fellow eye were recorded. Results. FCE were observed in 25 patients with age-related macular degeneration (ARMD), in 5 patients with high myopia, and in 8 patients with age-related choroidal atrophy (ARCA). Mean patient age was 80 ± 9.4 years. Mean CMCT was 86 ± 40 μm. Mean lumen diameter of the vessels inducing FCE was 131 ± 33 μm. Conclusions. FCE are relatively frequently encountered morphologic features of elderly patients with ARMD, high myopia, and ARCA, and have a distinct clinical and imaging morphology which differs from classically described chorioretinal folds. The lesions may commonly be mistaken for pigment epithelial detachments on ophthalmoscopy, may be associated with CNV in fellow eyes, and have a characteristic SD-OCT appearance.

scholarly journals Evaluation of retinal nerve fibre layer, optic nerve head, and macular ganglion cell analysis measurements for early glaucoma detection using spectral domain optical coherence tomography

2020 ◽  
Vol 9 (1) ◽  
pp. 186
Author(s):  
Rahul Bhardwaj ◽  
Sandeep Sharma ◽  
Rachana Gaur ◽  
Sindhuja Singh ◽  
Prakhar Chaudhary ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Open Angle Glaucoma ◽  
Retinal Nerve Fibre Layer ◽  
Spectral Domain ◽  
Optical Coherence ◽  
Early Glaucoma ◽  
Glaucoma Detection ◽  
Nerve Fibre Layer ◽  
Normal Controls ◽  
Sd Oct

Background: Glaucoma is the leading cause of irreversible blindness worldwide. It is very important to diagnose glaucoma in early stages so that timely management can be done. Spectral domain optical coherence tomography (SD-OCT), is a newer device which helps to diagnose glaucoma early. The aim of our study was to evaluate the RNFL, ONH, and mGCA (GCL+IPL) measurements for early glaucoma detection using spectral domain optical coherence tomography (SD-OCT).Methods: Total 30, POAG (primary open angle glaucoma) suspects were compared with 30 normal controls. The Cirrus HD-OCT optic disc cube 200 × 200 protocol was used to measure ONH, RNFL and macular parameters.Results: The average cpRNFL thickness of all quadrants was significantly lower in POAG suspects, (84.13±7.42 μm versus 103.85±8.95 μm, p<0.001). The superior GCL+IPL thickness of POAG suspects and controls was 75.75±2.60 μm and 80.05±1.74 μm, respectively, (p<0.001). The inferior GCL+IPL thickness of POAG suspects and controls was 75.98±2.59 μm and 80.00±1.79 μm, respectively, (p<0.001).Conclusions: The SD-OCT is an important device to diagnose POAG suspects, early. The GCA measurements and average RNFL (especially superior and inferior) measurements, both are equally good to discriminate between glaucoma suspects and normal controls.

scholarly journals Retinal thickness among normal myopic Filipinos using spectral domain optical coherence tomography

2020 ◽  
Vol 17 (2) ◽  
pp. 156-169
Author(s):  
Camille Elaine Zabala ◽  
Jubaida Mangondato-Aquino ◽  
Jose Ma. Martinez ◽  
John Mark De Leon
Keyword(s):  
Optical Coherence Tomography ◽  
High Myopia ◽  
Retinal Thickness ◽  
Spectral Domain ◽  
Pathologic Myopia ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Rnfl Thickness ◽  
Thickness Measurements ◽  
Sd Oct

Purpose: To determine mean macular and retinal nerve fiber layer (RNFL) thickness of myopic Filipinos using spectral domain optical coherence tomography (SD-OCT) and to evaluate influence of age, gender, and degree of myopia. Design: Observational clinic-based cohort. Methods: Participants were divided into two groups: low-moderate myopia [spherical equivalent (SE) -0.50 D to -6.00 D] and high-pathologic myopia (SE < -6.00 D and AL > 26.5 mm). Subgroup analyses between low myopia (refraction < -3.00 D or less) and moderate myopia (> -3.00 D to -6.00 D), and high myopia (> -6.00 D to -8.00 D) and pathologic myopia (more than -8.00 D) were done. Macular and RNFL thickness were measured by a SD-OCT and axial length (AL) with non-contact biometry. Results: Of 156 eyes, 88/156 (56%) had low-moderate myopia, 68/156 (44%) had high-pathologic myopia. There were 67/156 (43%) male and 89/156 (57%) female subjects. Mean central foveal subfield thickness measurements were 264 ± 24 μm for low myopia, 258 ± 17 μm for moderate myopia, 253 ± 25 μm for high myopia, and 218 ± 48 μm for pathologic myopia. Mean RNFL thickness measurements were 105.62 ± 3.89 μmfor low myopia, 97.6 ± 2.45 μm for moderate myopia, 85.9 ± 3.87 μm for high myopia, and 75.14 ± 3.89 μm for pathologic myopia. Average SE (p < 0.0001) decreased while AL (p < 0.0001) increased with more myopia. Myopia and age significantly affected macular and RNFL thickness parameters except for the following where only the degree of myopia was a significant factor: central foveal, temporal parafoveal, nasal perifoveal, inferior and nasal RNFL thicknesses. Conclusion: Retinal SD-OCT thickness measurements decreased with increasing level of myopia and age. Central foveal, temporal parafoveal, nasal perifoveal, inferior and nasal RNFL thicknesses may be more appropriate SD-OCT parameters among myopic Filipino patients to monitor for glaucoma since they may be less influenced by age.

scholarly journals Long-Term Natural Outcomes of Simple Hemorrhage Associated with Lacquer Crack in High Myopia: A Risk Factor for Myopic CNV?

2018 ◽  
Vol 2018 ◽  
pp. 1-7 ◽  
Author(s):  
Bing Liu ◽  
Xiongze Zhang ◽  
Lan Mi ◽  
Ling Chen ◽  
Feng Wen
Keyword(s):  
Risk Factor ◽  
High Myopia ◽  
Fundus Photography ◽  
Fundus Fluorescein Angiography ◽  
Cross Sectional ◽  
Ellipsoid Zone ◽  
Significant Difference ◽  
Sd Oct ◽  
Myopic Cnv ◽  
Central Fovea

Purpose. To investigate the relationship between simple hemorrhage (SH) associated with lacquer crack (LC) and myopic choroidal neovascularization (CNV) in high myopia.Methods. A cross-sectional evaluation including best-corrected visual acuity (BCVA), axial length, refractive error, color fundus photography, and spectral domain optical coherence tomography (SD-OCT) was performed in patients diagnosed with high myopia and SH. Fundus fluorescein angiography and indocyanine green angiography were performed if the eye was suspected with CNV.Results. Thirty-three eyes of 27 patients with SH were enrolled in the study. None of the eyes developed CNV at final examination following the occurrence of hemorrhage. Recurrent hemorrhage was observed in 36.5% of the eyes. Compared with the initial BCVA, the final BCVA was significantly improved (P<0.001) and correlated with the integrity of the ellipsoid zone in SD-OCT. There was no significant difference in the final BCVA between group 1 (LC crossed the central fovea) and group 2 (no LC crossed the central fovea) (P=0.299).Conclusions. SH associated with LC is not a risk factor for the development of myopic CNV in patients with high myopia. LCs have little influence on the final BCVA unless the integrity of the ellipsoid zone in the central fovea is disrupted.

Suprachoroidal haemhorrage and vortex vein varix: A potential association

2020 ◽  
pp. 112067212096403
Author(s):  
Paolo Milani ◽  
Marco Mazzola ◽  
Fulvio Bergamini
Keyword(s):  
Indocyanine Green ◽  
Multimodal Imaging ◽  
High Myopia ◽  
Temporal Part ◽  
Suprachoroidal Space ◽  
Potential Association ◽  
Suprachoroidal Hemorrhage ◽  
Summary Statement ◽  
Vortex Vein ◽  
Sd Oct

Purpose: To report on the association between a vortex vein varix and suprachoroidal hemorrhage. Case description: A healthy 60 years-old man with high myopia (–10 diopters) was seen because of sudden paracentral metamorphopsias after emesis. Multimodal imaging included Spectral-Domain Optical Coherence Tomography (SD-OCT), ultrasonography and retinal angiography with fluorescein and indocyanine green. His vision was 20/20 but clinical assessment and imaging procedures evaluations showed a suprachoroidal hemorrhage in the temporal part of the para-macular area. The lesion corresponded to a mild hypo-fluorescence area on fluorescein angiography and to a massive detachment of the inner part of the choroid from the suprachoroidal space on SD-OCT. Indocyanine green angiography disclosed engorgement of a big choroidal vessel in the area of the lesion. An adjacent vortex vein varix was found on SD-OCT. A few weeks later the suprachoroidal hemorrhage resolved spontaneously, whereas the vortex vein varix persisted. Conclusion: We speculate that vortex vein varixes might represent a risk factor for the occurrence of suprachoroidal hemorrhage in high myopia and that this association may be worth investigating. Summary statement: In a high myopia suprachoroidal hemorrhage might be secondary to vortex vein varixes.

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