Thickness of the Macula, Retinal Nerve Fiber Layer, and Ganglion Cell Layer in the Epiretinal Membrane: The Repeatability Study of Optical Coherence Tomography

2015 ◽  
Vol 56 (8) ◽  
pp. 4554 ◽  
Author(s):  
Haeng-Jin Lee ◽  
Min-Su Kim ◽  
Young-Joon Jo ◽  
Jung-Yeul Kim
Keyword(s):  
Optical Coherence Tomography ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Epiretinal Membrane ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer

scholarly journals Evaluation of Retinal Nerve Fiber Layer and Ganglion Cell Layer Thickness in Alzheimer’s Disease Using Optical Coherence Tomography

2020 ◽  
Vol Volume 14 ◽  
pp. 2995-3000
Author(s):  
Panitha Jindahra ◽  
Nitchanan Hengsiri ◽  
Pirada Witoonpanich ◽  
Anuchit Poonyathalang ◽  
Teeratorn Pulkes ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Retinal Nerve Fiber Layer ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Optical Coherence ◽  
Fiber Layer ◽  
Nerve Fiber Layer

scholarly journals Retinal Nerve Fiber Layer in Patients with Alcohol Use Disorder

2019 ◽  
Vol 9 (24) ◽  
pp. 5331 ◽  
Author(s):  
Sonia Álvarez-Sesmero ◽  
Francisco J. Povedano-Montero ◽  
Francisco Arias-Horcajadas ◽  
Marta Marín-Mayor ◽  
Patricia Navarrete-Chamorro ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Alcohol Consumption ◽  
Alcohol Use ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer

The objectives of the present study are to determine the effects of alcohol use on the retinal nerve fiber layer (RNFL) thickness and macular thickness of abstinent patients with alcohol use disorders (AUD) and to assess whether it correlates with alcohol consumption and/or cognitive impairment. This was a prospective, observational study that included 21 patients (42 eyes) and 21 controls (42 eyes). Patients met the criteria for early remission AUD at the moment of inclusion. We used optical coherence tomography to assess retinal thickness. Macular thickness in the group of AUD patients was lower in all quadrants (p < 0.05), with the exception of the peripheral and central. Regarding the nerve fiber layer in the macular and papilla areas, we found no significant differences. At the retina ganglion cell layer and in the nerve fiber of the macula, we found significant differences in all quadrants (p < 0.05), with the exception of the superior and superior nasal area, for the right eye. For the left eye, the only differences were found in the lower quadrant. Finally, when comparing the AUD patients to the controls, we found significant reductions in the ganglion cell layer of the macula in all quadrants in the former. There was a significant correlation between these findings and cognitive impairment (measured with the Test de Detección de Deterioro Cognitivo en Alcoholismo (TEDCA)), but not with alcohol consumption. Alcohol consumption is correlated with retinal harm and related cognitive decline.

scholarly journals Investigation of the pathophysiology of the retina and choroid in Parkinson's disease by optical coherence tomography

2021 ◽  
Author(s):  
Yasuaki Kamata ◽  
Naoto Hara ◽  
Tsukasa Satou ◽  
Takahiro Niida ◽  
Kazuo Mukuno
Keyword(s):  
Optical Coherence Tomography ◽  
Ganglion Cell ◽  
Nerve Fiber ◽  
Retinal Nerve Fiber Layer ◽  
Ganglion Cell Layer ◽  
Cell Layer ◽  
Plexiform Layer ◽  
Inner Plexiform Layer ◽  
Fiber Layer ◽  
Luminal Area

Abstract Purpose The pathology of Parkinson's disease (PD) is suspected to affect the retina and choroid. We investigated changes in the retina and choroid of patients with PD using optical coherence tomography. Methods We examined 14 patients with PD and 22 patients without PD. Patients without PD had no ophthalmic disease other than cataracts. In addition, it was also confirmed that there was no neurodegenerative disease. The retinal nerve fiber layer, ganglion cell layer + inner plexiform layer, and choroidal thickness were compared between both groups. Additionally, the choroidal image was divided into the choroid area, luminal area, and interstitial area using the binarization method, and the area of each region and the percentage of luminal area in the choroid area were analyzed. Results Patients with PD had a significantly thinner ganglion cell layer + inner plexiform layer compared to those without PD. The choroid area, luminal area, and interstitial area were significantly decreased in patients with PD compared to those without PD. Seven patients with PD who were successfully followed up showed decreased retinal nerve fiber layer and interstitial area after 3 years. Conclusion Autonomic nervous disorders and neurodegeneration in PD can cause thinning of the retina and choroid, as well as a reduction in the choroid area.

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