More to Stable Tears Than Thickness of the Tear Film Lipid Layer

2015 ◽  
Vol 56 (3) ◽  
pp. 1601-1601 ◽  
Author(s):  
B. J. Fenner ◽  
L. Tong
Keyword(s):  
Tear Film ◽  
Lipid Layer

New approaches to pharmacotherapy of allergic eye diseases

2015 ◽  
pp. 18-26
Author(s):  
Zoya Veselovska ◽  
Nataliia Veselovska
Keyword(s):  
Effective Means ◽  
Experimental Studies ◽  
Tear Film ◽  
Eye Diseases ◽  
Eye Drops ◽  
Lipid Layer ◽  
Ophthalmic Surgery ◽  
Promising Alternative ◽  
New Approaches ◽  
New Generation

The problem of studying the prеvalencе of allergic diseases of the eye and the search for new approaches and effective means to correct this condition does not lose its relevance. The presented data on the state of profound biochemical studies of the tear film in allergic conditions justify the expediency of the use of eye drops of a new generation. As a result of experimental studies on the effect on the lipid layer ectoine was discovered the mechanism of its therapeutic action. This paper presents compelling evidence that new eye drops based on natural molecules ectoine which are able to restore and maintain the functional state of the lipid layer of the tear film in the pharmacotherapy of аllergic diseases of anterior surface of the eye. The analyzes of multiple experimental data revealed the clear evidence of mechanisms of action on the eye and the first clinical experience with a new pharmacological agent testifies to its strong anti-inflammatory and regenerative effect due to the stabilization of the lipid layer of the tear film and the protection of the front surface of the eye tissue from the hyperosmolarity. It was confirmed by the subjective and objective reducing eye irritation and dryness in reducing itching and burning from the conjunctiva, to improve the moisture level of the surface of the eye, to reduce discomfort of the eyes. The drug can be used in children older than 2 years and adults, when wearing contact lenses, ophthalmic surgery and after an eye injury. Based on this, it can be conclude that the appearance in the arsenal of new-generation antiallergic eye drops (EYE-t) with sufficient efficacy and safety profile can be regarded as a promising alternative approach to the treatment of allergic and inflammatory eye diseases.

scholarly journals Molecular Organization of the Tear Film Lipid Layer

2010 ◽  
Vol 98 (3) ◽  
pp. 488a
Author(s):  
Antti Rantamäki ◽  
Jelena Telenius ◽  
Artturi Koivuniemi ◽  
Pipsa Kulovesi ◽  
Gerald Brezesinski ◽  
...  
Keyword(s):  
Tear Film ◽  
Molecular Organization ◽  
Lipid Layer

scholarly journals Image-based quantitative analysis of tear film lipid layer thickness for meibomian gland evaluation

2017 ◽  
Vol 16 (1) ◽  
Author(s):  
Hyeonha Hwang ◽  
Hee-Jae Jeon ◽  
Kin Choong Yow ◽  
Ho Sik Hwang ◽  
EuiHeon Chung
Keyword(s):  
Quantitative Analysis ◽  
Layer Thickness ◽  
Tear Film ◽  
Meibomian Gland ◽  
Lipid Layer

Assessment of the Tear Film Lipid Layer Thickness after Cataract Surgery

2016 ◽  
pp. 1-6 ◽  
Author(s):  
Jin Sun Kim ◽  
Hun Lee ◽  
Seonghee Choi ◽  
Eung Kweon Kim ◽  
Kyoung Yul Seo ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Layer Thickness ◽  
Tear Film ◽  
Lipid Layer

Increased Tear Film Lipid Layer Thickness with the use of two Novel Lubricating Eyedrops

2005 ◽  
Vol 3 ◽  
pp. S83
Author(s):  
Donald R. Korb ◽  
Robert C. Scaffidi ◽  
Jack V. Greiner ◽  
Kenneth R. Kenyon ◽  
John P. Herman ◽  
...  
Keyword(s):  
Layer Thickness ◽  
Tear Film ◽  
Lipid Layer

scholarly journals Improving Stability of Tear Film Lipid Layer via Concerted Action of Two Drug Molecules: A Biophysical View

2018 ◽  
Vol 114 (3) ◽  
pp. 104a
Author(s):  
Yana Nencheva ◽  
Agnieszka Olzynska ◽  
Adela Melcrova ◽  
Georgi As Georgiev ◽  
Philippe Daull ◽  
...  
Keyword(s):  
Tear Film ◽  
Concerted Action ◽  
Lipid Layer ◽  
Drug Molecules
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