Effect of Diabetic Macular Edema on Peripapillary Retinal Nerve Fiber Layer Thickness Profiles

2014 ◽  
Vol 55 (7) ◽  
pp. 4213 ◽  
Author(s):  
Duck Jin Hwang ◽  
Eun Ji Lee ◽  
Sang Yoon Lee ◽  
Kyu Hyung Park ◽  
Se Joon Woo
Keyword(s):  
Macular Edema ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Diabetic Macular Edema ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Retinal Nerve Fiber

scholarly journals Comparison of Retinal Nerve Fiber Layer Thickness Changes after Intravitreal Bevacizumab in Patients of Diabetic Macular Edema

2018 ◽  
Vol 24 (1) ◽  
Author(s):  
Muhammad Shaheer ◽  
Asad Aslam Khan ◽  
Nasir Ahmed ◽  
Tehseen Mahmood Mahju ◽  
Ummarah Rasheed
Keyword(s):  
Macular Edema ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Retinal Nerve Fiber Layer ◽  
Intravitreal Bevacizumab ◽  
Post Injection ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Retinal Nerve Fiber

Diabetic macular edema is one of the leading causes of visual loss in diabetic patients. However, the impact of medicinal treatment on the occurrence of macular edema remained elusive. Objectives: This study was designed to determine the effect of intravitreal bevacizumab in patients of diabetic macular edema.Methods: An interventional study was conducted on patients that underwent pre-injection and one-month post-injection OCT for RNFL thickness. OCT was performed by researchers and findings were recorded accordingly. The retinal nerve fiber layer thickness was measured in superior, inferior halves and total average thickness. Pre- and post-injection OCT were conduced and macular thickness were documented. Results: The mean retinal nerve fiber layer thickness was decreased in superior and inferior halves as well as in the total thickness. Conclusion: Intra vitreal bevacizumab decreases the retinal nerve fiber layer thickness. Large randomized controlled trials are required to establish or rule out any association between this decrease in thickness and incidence if glaucoma in such patients.

Comparative Analysis of Retinal Nerve Fiber Layer Thickness between Normal and Mild to Moderately Myopic Eyes

2021 ◽  
Vol 37 (4) ◽  
Author(s):  
Gul Nasreen ◽  
Shaheer Suhail Sarwar ◽  
Irfana Bibi ◽  
Muhammad Arslan Ashraf
Keyword(s):  
Optical Coherence Tomography ◽  
Nerve Fiber ◽  
Layer Thickness ◽  
Retinal Nerve Fiber Layer ◽  
Fiber Layer ◽  
Nerve Fiber Layer ◽  
Nerve Fiber Layer Thickness ◽  
Rnfl Thickness ◽  
The Mean ◽  
Retinal Nerve Fiber

Purpose:  To determine the difference between mean retinal nerve fiber layer (RNFL) thickness in myopic eyes (up to -6.00D) and normal eyes. Study Design:  Descriptive observational study. Place and Duration of the Study:  Eye department of Mayo hospital Lahore, from February 2019 to April 2019. Methods:  We compared the mean RNFL between 58 myopic eyes (up to -6.00 D) and age matched 60 normal eyes. The age of the participants was between 12 to 42 years. Complete ocular examination was done and RNFL thickness was measured by using Optical coherence tomography (NIDEX RS-33.0, software-ex 1.5.2).Data was analyzed by independent sample t-test by using SPSS; with P < .05 as significant. Results:  The mean difference among these groups was 5.852 µm with (SE: 1.929). Mean RNFL thickness in myopic group was (95.93 ± 10.158µm) with (SE: 1.334). The result for mean RNFL thickness in myopic eyes was distributed normally as P < .03. Mean RNFL in normal group was (101.78 ± 10.774 µm) with (SE: 1.391), and the result of mean RNFL thickness measured in normal eyes was not distributed normally as P < .20. The results showed that there is a statistically significant difference between mean RNFL thickness measured in normal versus myopic eyes as (P < .003). Conclusion:  There is a significance difference between mean RNFL thickness between myopic eyes and normal eyes as measured by OCT. Careful interpretation of RNFL data in myopic eyes is recommended to avoid misdiagnosis with glaucoma. Key Words:  Retinal Nerve Fiber Layer thickness, Myopia, Optical Coherence Tomography.

Sign in / Sign up

Export Citation Format

Share Document