In Vivo Imaging of a New Indocyanine Green Micelle Formulation in an Animal Model of Laser-Induced Choroidal Neovascularization

2014 ◽  
Vol 55 (10) ◽  
pp. 6204 ◽  
Author(s):  
Johanna Meyer ◽  
Alexander Cunea ◽  
Dagmar Sonntag-Bensch ◽  
Pia Welker ◽  
Kai Licha ◽  
...  
Keyword(s):  
Animal Model ◽  
Indocyanine Green ◽  
Choroidal Neovascularization ◽  
In Vivo Imaging

scholarly journals In vivo imaging of rapid deformation and strain in an animal model of traumatic brain injury

2006 ◽  
Vol 39 (6) ◽  
pp. 1086-1095 ◽  
Author(s):  
Philip V. Bayly ◽  
Erin E. Black ◽  
Rachel C. Pedersen ◽  
Elizabeth P. Leister ◽  
Guy M. Genin
Keyword(s):  
Traumatic Brain Injury ◽  
Animal Model ◽  
Brain Injury ◽  
In Vivo Imaging ◽  
Rapid Deformation

In vivo Imaging with a Fundus Camera in a Rat Model of Laser-Induced Choroidal Neovascularization

2014 ◽  
Vol 231 (2) ◽  
pp. 117-123 ◽  
Author(s):  
Alexander Cunea ◽  
Johanna Meyer ◽  
Christoph Russmann ◽  
Kai Licha ◽  
Pia Welker ◽  
...  
Keyword(s):  
Choroidal Neovascularization ◽  
Rat Model ◽  
In Vivo Imaging ◽  
Fundus Camera

In vivo imaging of early signs of dopaminergic neuronal death in an animal model of Parkinson's disease

2018 ◽  
Vol 114 ◽  
pp. 74-84 ◽  
Author(s):  
Nicoletta Rizzi ◽  
Electra Brunialti ◽  
Silvia Cerri ◽  
Greta Cermisoni ◽  
Giovanna Levandis ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Animal Model ◽  
In Vivo Imaging ◽  
Neuronal Death ◽  
Early Signs

scholarly journals In vivo imaging and radioiodine therapy following sodium iodide symporter gene transfer in animal model of intracerebral gliomas

Gene Therapy ◽  
2002 ◽  
Vol 9 (17) ◽  
pp. 1139-1145 ◽  
Author(s):  
J-Y Cho ◽  
D HY Shen ◽  
W Yang ◽  
B Williams ◽  
T LF Buckwalter ◽  
...  
Keyword(s):  
Animal Model ◽  
Gene Transfer ◽  
In Vivo Imaging ◽  
Sodium Iodide ◽  
Radioiodine Therapy ◽  
Sodium Iodide Symporter

scholarly journals In Vivo Imaging With Confirmation by Histopathology for Increased Rigor and Reproducibility in Translational Research: A Review of Examples, Options, and Resources

ILAR Journal ◽  
2018 ◽  
Vol 59 (1) ◽  
pp. 80-98 ◽  
Author(s):  
Kathleen Gabrielson ◽  
Robert Maronpot ◽  
Sébastien Monette ◽  
Coraline Mlynarczyk ◽  
Yuval Ramot ◽  
...  
Keyword(s):  
Animal Model ◽  
In Vivo Imaging ◽  
Image Interpretation ◽  
Imaging Data ◽  
Case Examples ◽  
Animal Models Of Disease ◽  
Molecular Features ◽  
Wide Range ◽  
Models Of Disease

Abstract Preclinical noninvasive imaging can be an indispensable tool for studying animal models of disease. In vivo imaging to assess anatomical, functional, and molecular features requires verification by a comparison to the macroscopic and microscopic morphological features, since all noninvasive in vivo imaging methods have much lower resolution than standard histopathology. Comprehensive pathological evaluation of the animal model is underutilized; yet, many institutions have veterinary or human pathologists with necessary comparative pathology expertise. By performing a rigorous comparison to gross or histopathology for image interpretation, these trained individuals can assist scientists with the development of the animal model, experimental design, and evaluation of the in vivo imaging data. These imaging and pathology corroboration studies undoubtedly increase scientific rigor and reproducibility in descriptive and hypothesis-driven research. A review of case examples including ultrasound, nuclear, optical, and MRI is provided to illustrate how a wide range of imaging modalities data can be confirmed by gross or microscopic pathology. This image confirmation and authentication will improve characterization of the model and may contribute to decreasing costs and number of animals used and to more rapid translation from preclinical animal model to the clinic.

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