Effect of Ginkgo Biloba on Visual Field and Contrast Sensitivity in Chinese Patients With Normal Tension Glaucoma: A Randomized, Crossover Clinical Trial

2014 ◽  
Vol 55 (1) ◽  
pp. 110 ◽  
Author(s):  
Xinxing Guo ◽  
Xiangbin Kong ◽  
Rui Huang ◽  
Ling Jin ◽  
Xiaohu Ding ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Visual Field ◽  
Contrast Sensitivity ◽  
Ginkgo Biloba ◽  
Normal Tension Glaucoma ◽  
Chinese Patients

scholarly journals Association of ocular blood flow and contrast sensitivity in normal tension glaucoma

2021 ◽  
Author(s):  
David Kuerten ◽  
Matthias Fuest ◽  
Peter Walter ◽  
Babac Mazinani ◽  
Niklas Plange
Keyword(s):  
Blood Flow ◽  
Visual Field ◽  
Contrast Sensitivity ◽  
Visual Field Defect ◽  
Prospective Trial ◽  
Normal Tension Glaucoma ◽  
Ocular Blood Flow ◽  
Retinal Blood Flow ◽  
Control Group ◽  
Field Defect

Abstract Purpose To investigate the relationship of ocular blood flow (via arteriovenous passage time, AVP) and contrast sensitivity (CS) in healthy as well as normal tension glaucoma (NTG) subjects. Design Mono-center comparative prospective trial Methods Twenty-five NTG patients without medication and 25 healthy test participants were recruited. AVP as a measure of retinal blood flow was recorded via fluorescein angiography after CS measurement using digital image analysis. Association of AVP and CS at 4 spatial frequencies (3, 6, 12, and 18 cycles per degree, cpd) was explored with correlation analysis. Results Significant differences regarding AVP, visual field defect, intraocular pressure, and CS measurement were recorded in-between the control group and NTG patients. In NTG patients, AVP was significantly correlated to CS at all investigated cpd (3 cpd: r =  − 0.432, p< 0.03; 6 cpd: r =  − 0.629, p< 0.0005; 12 cpd: r =  − 0.535, p< 0.005; and 18 cpd: r =  − 0.58, p< 0.001), whereas no significant correlations were found in the control group. Visual acuity was significantly correlated to CS at 6, 12, and 18 cpd in NTG patients (r =  − 0.68, p< 0.002; r =  − 0.54, p< .02, and r =  − 0.88, p< 0.0001 respectively), however not in healthy control patients. Age, visual field defect MD, and PSD were not significantly correlated to CS in in the NTG group. MD and PSD were significantly correlated to CS at 3 cpd in healthy eyes (r = 0.55, p< 0.02; r =  − 0.47, p< 0.03). Conclusion Retinal blood flow alterations show a relationship with contrast sensitivity loss in NTG patients. This might reflect a disease-related link between retinal blood flow and visual function. This association was not recorded in healthy volunteers.

Intraocular Pressure Reduction in the Treatment of Normal-Tension Glaucoma

2020 ◽  
pp. 67-72
Author(s):  
Alan D. Penman ◽  
Kimberly W. Crowder ◽  
William M. Watkins
Keyword(s):  
Clinical Trial ◽  
Intraocular Pressure ◽  
Visual Field ◽  
Natural History ◽  
Visual Loss ◽  
Normal Tension Glaucoma ◽  
Pressure Reduction ◽  
Glaucomatous Damage ◽  
Intraocular Pressure Reduction ◽  
History Of

The Collaborative Normal-Tension Glaucoma Study (CNTGS) was a randomized clinical trial to determine the effectiveness of a 30% reduction in intraocular pressure (IOP) (using either medical therapy or filtration surgery) on visual field (VF) progression in eyes with normal-tension glaucoma. The study found that reducing the IOP of patients with normal-tension glaucoma by 30% is beneficial to prevent progression of glaucomatous damage if the visual effects of cataracts are excluded from consideration. However, because not all untreated patients progressed, the natural history of normal-tension glaucoma must be considered before embarking on IOP reduction with therapy that may exacerbate cataract formation, unless normal-tension glaucoma threatens serious visual loss.

Effect of Ginkgo biloba extract on preexisting visual field damage in normal tension glaucoma

Ophthalmology ◽  
2003 ◽  
Vol 110 (2) ◽  
pp. 359-362 ◽  
Author(s):  
Luciano Quaranta ◽  
Sabina Bettelli ◽  
Maurizio G Uva ◽  
Francesco Semeraro ◽  
Raffaele Turano ◽  
...  
Keyword(s):  
Visual Field ◽  
Ginkgo Biloba ◽  
Normal Tension Glaucoma ◽  
Ginkgo Biloba Extract ◽  
Visual Field Damage

scholarly journals Association of Vistech contrast sensitivity and visual field findings in glaucoma.

1991 ◽  
Vol 75 (9) ◽  
pp. 558-560 ◽  
Author(s):  
W E Sponsel ◽  
K L DePaul ◽  
J F Martone ◽  
M B Shields ◽  
A R Ollie ◽  
...  
Keyword(s):  
Visual Field ◽  
Contrast Sensitivity

Effect of Trabeculectomy on Visual Field Performance in Central 30° Field in Progressive Normal-tension Glaucoma

Ophthalmology ◽  
1997 ◽  
Vol 104 (2) ◽  
pp. 197-201 ◽  
Author(s):  
Nobuyuki Koseki ◽  
Makoto Araie ◽  
Shiroaki Shirato ◽  
Seiichiro Yamamoto
Keyword(s):  
Visual Field ◽  
Field Performance ◽  
Normal Tension Glaucoma
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