A Nicotinic Acetylcholine Receptor Agonist Prevents Loss of Retinal Ganglion Cells in a Glaucoma Model

Kazuhiro Iwamoto; Patrick Birkholz; Austin Schipper; David Mata; David M. Linn; Cindy L. Linn

doi:10.1167/iovs.13-12688

A Nicotinic Acetylcholine Receptor Agonist Prevents Loss of Retinal Ganglion Cells in a Glaucoma Model

Investigative Opthalmology & Visual Science ◽

10.1167/iovs.13-12688 ◽

2014 ◽

Vol 55 (2) ◽

pp. 1078 ◽

Cited By ~ 19

Author(s):

Kazuhiro Iwamoto ◽

Patrick Birkholz ◽

Austin Schipper ◽

David Mata ◽

David M. Linn ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Retinal Ganglion Cells ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Ganglion Cells ◽

Retinal Ganglion ◽

Nicotinic Acetylcholine

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Synaptic pattern of nicotinic acetylcholine receptor α7 and β2 subunits on the direction-selective retinal ganglion cells in the postnatal mouse retina

Experimental Eye Research ◽

10.1016/j.exer.2014.02.021 ◽

2014 ◽

Vol 122 ◽

pp. 54-64 ◽

Cited By ~ 6

Author(s):

Hyun Jin Kim ◽

Chang Jin Jeon

Keyword(s):

Acetylcholine Receptor ◽

Retinal Ganglion Cells ◽

Nicotinic Acetylcholine Receptor ◽

Ganglion Cells ◽

Mouse Retina ◽

Retinal Ganglion ◽

Nicotinic Acetylcholine

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Differential effects of axotomy on substance p-containing and nicotinic acetylcholine receptor-containing retinal ganglion cells: time course of degeneration and effects of nerve growth factor

Neuroscience ◽

10.1016/0306-4522(90)90013-t ◽

1990 ◽

Vol 36 (3) ◽

pp. 699-723 ◽

Cited By ~ 6

Author(s):

D. Ehrlich ◽

K. Keyser ◽

M. Manthorpe ◽

S. Varon ◽

H.J. Karten

Keyword(s):

Nerve Growth Factor ◽

Growth Factor ◽

Substance P ◽

Acetylcholine Receptor ◽

Retinal Ganglion Cells ◽

Nicotinic Acetylcholine Receptor ◽

Time Course ◽

Ganglion Cells ◽

Retinal Ganglion ◽

Nicotinic Acetylcholine

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Expression of Nicotinic Acetylcholine Receptor α4 and β2 Subunits on Direction-Selective Retinal Ganglion Cells in the Rabbit

ACTA HISTOCHEMICA ET CYTOCHEMICA ◽

10.1267/ahc.16024 ◽

2017 ◽

Vol 50 (1) ◽

pp. 29-37

Author(s):

Jun-Seok Lee ◽

Hyun-Jin Kim ◽

Chang-Hyun Ahn ◽

Chang-Jin Jeon

Keyword(s):

Acetylcholine Receptor ◽

Retinal Ganglion Cells ◽

Nicotinic Acetylcholine Receptor ◽

Ganglion Cells ◽

Retinal Ganglion ◽

Nicotinic Acetylcholine

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Differential co-localization of nicotinic acetylcholine receptor subunits with calcium-binding proteins in retinal ganglion cells

Brain Research ◽

10.1016/s0006-8993(97)81715-5 ◽

1997 ◽

Vol 774 (1-2) ◽

pp. 250-255 ◽

Cited By ~ 10

Author(s):

Claudia M Araki ◽

Raquel S Pires ◽

Luiz R.G Britto ◽

Jon M Lindstrom ◽

Harvey J Karten ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Retinal Ganglion Cells ◽

Nicotinic Acetylcholine Receptor ◽

Calcium Binding ◽

Binding Proteins ◽

Ganglion Cells ◽

Calcium Binding Proteins ◽

Retinal Ganglion ◽

Nicotinic Acetylcholine

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Alpha7 nicotinic acetylcholine receptor agonist promotes retinal ganglion cell function via modulating GABAergic presynaptic activity in a chronic glaucomatous model

Scientific Reports ◽

10.1038/s41598-017-02092-6 ◽

2017 ◽

Vol 7 (1) ◽

Cited By ~ 13

Author(s):

Xujiao Zhou ◽

Yun Cheng ◽

Rong Zhang ◽

Gang Li ◽

Boqi Yang ◽

...

Keyword(s):

Ganglion Cell ◽

Acetylcholine Receptor ◽

Retinal Ganglion Cell ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Cell Function ◽

Retinal Ganglion ◽

Nicotinic Acetylcholine ◽

Alpha7 Nicotinic Acetylcholine Receptor ◽

Retinal Ganglion Cell Function

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Epibatidine, a nicotinic acetylcholine receptor agonist, inhibits the capsaicin response in dorsal root ganglion neurons

Brain Research ◽

10.1016/s0006-8993(01)03028-1 ◽

2001 ◽

Vol 919 (1) ◽

pp. 166-168 ◽

Cited By ~ 3

Author(s):

Xu-Feng Zhang ◽

David G. McKenna ◽

Clark A. Briggs

Keyword(s):

Dorsal Root Ganglion ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Dorsal Root ◽

Receptor Agonist ◽

Dorsal Root Ganglion Neurons ◽

Nicotinic Acetylcholine ◽

Ganglion Neurons

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Protein-ligand interactions. 6 nicotinic acetylcholine receptor agonist activity of isoquinoline alkaloids

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/s0960-894x(96)00429-5 ◽

1996 ◽

Vol 6 (23) ◽

pp. 2801-2806 ◽

Cited By ~ 5

Author(s):

C.G. Whiteley ◽

S. Daya

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Agonist Activity ◽

Isoquinoline Alkaloids ◽

Nicotinic Acetylcholine ◽

Protein Ligand Interactions ◽

Ligand Interactions

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In Vitro Pharmacological Characterization of a Novel Selective α7 Neuronal Nicotinic Acetylcholine Receptor Agonist ABT-107

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.110.167072 ◽

2010 ◽

Vol 334 (3) ◽

pp. 863-874 ◽

Cited By ~ 40

Author(s):

John Malysz ◽

David J. Anderson ◽

Jens H. Grønlien ◽

Jianguo Ji ◽

William H. Bunnelle ◽

...

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Pharmacological Characterization ◽

Nicotinic Acetylcholine

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P4-310: Preclinical characterization of a selective alpha-7 neuronal nicotinic acetylcholine receptor agonist ABT-126: A novel therapeutic agent for the treatment of cognitive impairment in Alzheimer's disease and schizophrenia

Alzheimer s & Dementia ◽

10.1016/j.jalz.2013.05.1755 ◽

2013 ◽

Vol 9 ◽

pp. P817-P818 ◽

Cited By ~ 5

Author(s):

Robert Bitner ◽

David Anderson ◽

Karla Drescher ◽

Kathy Kohlhaas ◽

Halvard Gronlien ◽

...

Keyword(s):

Cognitive Impairment ◽

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Therapeutic Agent ◽

Neuronal Nicotinic Acetylcholine Receptor ◽

Nicotinic Acetylcholine ◽

Alpha 7 ◽

Novel Therapeutic

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Monocytes primed with GTS-21/α7 nAChR (nicotinic acetylcholine receptor) agonist develop anti-inflammatory memory

QJM ◽

10.1093/qjmed/hcx014 ◽

2017 ◽

pp. hcx014 ◽

Cited By ~ 2

Author(s):

Xi Yang ◽

Caiqi Zhao ◽

Xiu Chen ◽

Lubin Jiang ◽

Xiao Su

Keyword(s):

Acetylcholine Receptor ◽

Nicotinic Acetylcholine Receptor ◽

Receptor Agonist ◽

Nicotinic Acetylcholine ◽

Α7 Nachr ◽

Anti Inflammatory

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