A Systematic Review on Zinc for the Prevention and Treatment of Age-Related Macular Degeneration

2013 ◽  
Vol 54 (6) ◽  
pp. 3985 ◽  
Author(s):  
Rohini Vishwanathan ◽  
Mei Chung ◽  
Elizabeth J. Johnson
Keyword(s):  
Systematic Review ◽  
Macular Degeneration ◽  
Age Related Macular Degeneration ◽  
Age Related ◽  
Prevention And Treatment

scholarly journals Algorithms for the Automated Analysis of Age-Related Macular Degeneration Biomarkers on Optical Coherence Tomography: A Systematic Review

2017 ◽  
Vol 6 (4) ◽  
pp. 10 ◽  
Author(s):  
Maximilian W.M. Wintergerst ◽  
Thomas Schultz ◽  
Johannes Birtel ◽  
Alexander K. Schuster ◽  
Norbert Pfeiffer ◽  
...  
Keyword(s):  
Systematic Review ◽  
Optical Coherence Tomography ◽  
Macular Degeneration ◽  
Automated Analysis ◽  
Age Related Macular Degeneration ◽  
Optical Coherence ◽  
Age Related

scholarly journals Systematic review and meta-analysis of the association between complementary factor H Y402H polymorphisms and age-related macular degeneration

2006 ◽  
Vol 15 (18) ◽  
pp. 2784-2790 ◽  
Author(s):  
Ammarin Thakkinstian ◽  
Pearline Han ◽  
Mark McEvoy ◽  
Wayne Smith ◽  
Josephine Hoh ◽  
...  
Keyword(s):  
Systematic Review ◽  
Macular Degeneration ◽  
Meta Analysis ◽  
Factor H ◽  
Age Related Macular Degeneration ◽  
Complementary Factor ◽  
Age Related

scholarly journals The prevalence of age-related Macular degeneration in Indian Population: a systematic review

2015 ◽  
Vol 18 (3) ◽  
pp. A180
Author(s):  
N. Likhar ◽  
R.K. Mothe ◽  
R. Kanukula ◽  
C. Shah ◽  
A. Dang
Keyword(s):  
Systematic Review ◽  
Macular Degeneration ◽  
Indian Population ◽  
Age Related Macular Degeneration ◽  
Age Related

scholarly journals Efficacy Comparison of Intravitreal Anti-VEGF Therapy for Three Subtypes of Neovascular Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 2018 ◽  
pp. 1-10 ◽  
Author(s):  
Jianqing Li ◽  
Jiayi Xu ◽  
Yiyi Chen ◽  
Jiaju Zhang ◽  
Yihong Cao ◽  
...  
Keyword(s):  
Systematic Review ◽  
Macular Degeneration ◽  
Meta Analysis ◽  
Age Related Macular Degeneration ◽  
Cochrane Library ◽  
Anti Vegf ◽  
Age Related ◽  
Significant Difference ◽  
The Mean

Purpose. Intravitreal antivascular endothelial growth factor (anti-VEGF) therapy has been widely used for the treatment of neovascularization (NV) secondary to age-related macular degeneration (AMD). This study aimed to compare the efficacy among different subtypes of neovascular age-related macular degeneration (nAMD). Methods. PubMed, Embase, and the Cochrane Library were searched for eligible studies. We performed meta-analysis using Review Manager 5.3 and Stata/SE 12.0. Results. A total of 24 studies met our inclusion criteria and were included in the systematic review. At 3 months, the mean logarithm of the minimum angle of resolution (logMAR) improvements were −0.09, −0.18, and −0.23 for type 1, 2, and 3, respectively, while the mean macular thickness (MT) changes were −104.83, −130.76, and −196.29 μm. At 12 months, the mean changes in Early Treatment of Diabetic Retinopathy Study (ETDRS) letters were 6.38, 8.12, and 9.37, while the MT decrease was 126.51, 126.52, and 139.85 μm, respectively. However, statistically significant difference was only found between type 1 and 3 in vision improvement, both in the short term (p=0.0002) and long term (p=0.01). Conclusions. The reactivity to VEGF inhibitors varied among different subtypes of nAMD. The efficacy of intravitreal anti-VEGF therapy in type 3 nAMD was statistically better than type 1 when considering vision improvement at 3 and 12 months. Thus, the lesion subtype is a predictor for the treatment outcome which can help guide prognosis.

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