Influence of Macular Pigment on Retinal Straylight in Healthy Eyes

2013 ◽  
Vol 54 (5) ◽  
pp. 3505 ◽  
Author(s):  
Sien Jongenelen ◽  
Jos J. Rozema ◽  
Marie-José Tassignon
Keyword(s):  
Macular Pigment ◽  
Healthy Eyes ◽  
Retinal Straylight

Retinal Straylight as a Function of Age and Ocular Biometry in Healthy Eyes

2010 ◽  
Vol 51 (5) ◽  
pp. 2795 ◽  
Author(s):  
Jos J. Rozema ◽  
Thomas J. T. P. Van den Berg ◽  
Marie-José Tassignon
Keyword(s):  
Ocular Biometry ◽  
Healthy Eyes ◽  
Retinal Straylight

Is macular pigment optical density really involved in fixation preference?

2018 ◽  
Vol 28 (4) ◽  
pp. 454-458
Author(s):  
Kadriye Erkan Turan ◽  
Ali Bulent Cankaya ◽  
Hande Taylan Sekeroglu ◽  
Onur Inam ◽  
Sevilay Karahan
Keyword(s):  
Body Mass Index ◽  
Body Mass ◽  
Optical Density ◽  
Density Measurement ◽  
Macular Pigment ◽  
Healthy Children ◽  
Macular Pigment Optical Density ◽  
Fixation Preference ◽  
Healthy Eyes ◽  
Density Results

Purpose: To evaluate macular pigment optical density in healthy children and to compare the values with those of strabismic children with respect to fixation preference. Methods: The study recruited 54 healthy and 41 strabismic children. Two groups were matched in terms of gestational age, birth weight, and body mass index. All participants underwent complete ophthalmological evaluation and macular pigment optical density measurement and filled a self-reported food frequency questionnaire. Strabismic children were categorized according to fixation preference. Results: The mean age was 9.87 ± 2.39 years in healthy children and 9.07 ± 2.07 years in children with strabismus (p = 0.091). Mean macular pigment optical density was 0.23 ± 0.25 in healthy eyes and 0.25 ± 0.27 in non-preferred eyes of strabismic children (p = 0.964). Macular pigment optical density was significantly higher in preferred eyes of strabismic children (0.43 ± 0.34) compared to non-preferred eyes (p = 0.004) and healthy eyes (p = 0.001). There was a difference of macular pigment optical density between both eyes in patients with grades 1, 2, and 3 fixation preference, whereas patients with grade 4 preference had similar macular pigment optical density in both eyes (p = 0.008). There was a statistically significant positive correlation between macular pigment optical density in preferred eyes and body mass index (r = 0.354, p = 0.023). Conclusion: Preferred eyes of children with strabismus seem to have higher macular pigment optical density readings. This difference may emerge from the higher tendency of recognizing the flicker stimulus while preferred eye is under testing. Similar macular pigment optical density in healthy and non-preferred eyes and the fact that both lower than preferred eyes remain unexplained. It should be kept in mind that macular pigment optical density results should be carefully interpreted and macular pigment optical density in cases with strabismus should be further investigated.

Study of relationship between choroidal thickness and indicators of state macular pigment in young patients with myopic refraction

2020 ◽  
pp. 14-15
Author(s):  
L.V. Bushnina ◽  
◽  
N.V. Pomytkina ◽  
Е.L. Sorokin ◽  
◽  
...  
Keyword(s):  
Choroidal Thickness ◽  
Young Patients ◽  
Macular Pigment

Актуальность. Среди инвалидизирующих осложнений миопии атрофическая макулопатия занимает одно из лидирующих мест. Выявление взаимосвязи между состоянием хориоидеи и макулярного пигмента поможет в разработке методов выявления группы риска миопических атрофических макулярных изменений. Цель. Выяснение наличия взаимосвязи между количественными показателями состояния макулярного пигмента и толщиной хориоидеи у молодых пациентов с миопической рефракцией. Материал и методы. Обследовано 36 пациентов (36 глаз) молодого возраста с миопией. Кроме стандартных методов обследования пациентам проводилось измерение размера переднезадней оси (ПЗО) глаза, толщины хориоидеи, показателей состояния макулярного пигмента. Результаты. Выявлена прямая корреляция между размерами ПЗО и площадью распределения макулярного пигмента (r=0,489, p<0,01), объемом оптической плотности макулярного пигмента (r=0,397, p<0,05); обратная корреляция между толщиной хориоидеи, площадью распределения макулярного пигмента и объемом оптической плотности макулярного пигмента (r=-0,421, p<0,05 и r=-0,415, p<0,05 соответственно). Не выявлено корреляции между показателем оптической плотности макулярного пигмента и толщиной хориоидеи, размерами ПЗО. Это не укладывается в традиционное понимание того, что атрофический процесс наружных слоев сетчатки связан с недостатком их кровоснабжения, а, следовательно, с истончением хориоидеи. Выводы. По мере возрастания размеров ПЗО и уменьшения толщины хориоидеи увеличивается площадь распределения макулярного пигмента и объем его оптической плотности, хотя закономерных изменений оптической плотности макулярного пигмента не выявлено. Дальнейшие исследования динамики изменений макулярных пигментов при осевой миопии могут помочь в разработке методов прогнозирования формирования миопических изменений макулярной зоны

The role of the macular pigment optical density measurement in the diagnosis of eye diseases

2016 ◽  
Vol 16 (4) ◽  
pp. 197-200
Author(s):  
E.N. Eskina ◽  
◽  
E.A. Egorov ◽  
A.V. Belogurova ◽  
А.А. Gvetadze ◽  
...  
Keyword(s):  
Optical Density ◽  
Density Measurement ◽  
Macular Pigment ◽  
Eye Diseases ◽  
Macular Pigment Optical Density ◽  
Optical Density Measurement

scholarly journals Macular Pigment Optical Density and Photoreceptor Outer Segment Length as Predisease Biomarkers for Age-Related Macular Degeneration

2020 ◽  
Vol 9 (5) ◽  
pp. 1347 ◽  
Author(s):  
Norihiro Nagai ◽  
Sakiko Minami ◽  
Misa Suzuki ◽  
Hajime Shinoda ◽  
Toshihide Kurihara ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Optical Density ◽  
Outer Segment ◽  
Macular Pigment ◽  
Age Related Macular Degeneration ◽  
Segment Length ◽  
Macular Pigment Optical Density ◽  
Photoreceptor Outer Segment ◽  
Age Related ◽  
Fellow Eyes

To explore predisease biomarkers, which may help screen for the risk of age-related macular degeneration (AMD) at very early stages, macular pigment optical density (MPOD) and photoreceptor outer segment (PROS) length were analyzed. Thirty late AMD fellow eyes, which are at high risk and represent the predisease condition of AMD, were evaluated and compared with 30 age-matched control eyes without retinal diseases; there was no early AMD involvement in the AMD fellow eyes. MPOD was measured using MPS2® (M.E. Technica Co. Ltd., Tokyo, Japan), and PROS length was measured based on optical coherence tomography images. MPOD levels and PROS length in the AMD fellow eyes were significantly lower and shorter, respectively, than in control eyes. MPOD and PROS length were positively correlated in control eyes (R = 0.386; p = 0.035) but not in AMD fellow eyes. Twenty (67%) AMD fellow eyes met the criteria of MPOD < 0.65 and/or PROS length < 35 μm, while only five (17%) control eyes did. After adjusting for age and sex, AMD fellow eyes more frequently satisfied the definition (p < 0.001; 95% confidence interval, 3.50–60.4; odds ratio, 14.6). The combination of MPOD and PROS length may be a useful biomarker for screening predisease AMD patients, although further studies are required in this regard.

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