scholarly journals Relationships among Multifocal Electroretinogram Amplitude, Visual Field Sensitivity, and SD-OCT Receptor Layer Thicknesses in Patients with Retinitis Pigmentosa

2012 ◽  
Vol 53 (2) ◽  
pp. 833 ◽  
Author(s):  
Yuquan Wen ◽  
Martin Klein ◽  
Donald C. Hood ◽  
David G. Birch
Keyword(s):  
Visual Field ◽  
Retinitis Pigmentosa ◽  
Multifocal Electroretinogram ◽  
Field Sensitivity ◽  
Sd Oct ◽  
Receptor Layer

scholarly journals A Prediction Method of Visual Field Sensitivity Using Fundus Autofluorescence Images in Patients With Retinitis Pigmentosa

2020 ◽  
Vol 61 (10) ◽  
pp. 51
Author(s):  
Tatsuya Inoue ◽  
Kosuke Nakajima ◽  
Yohei Hashimoto ◽  
Shotaro Asano ◽  
Kohdai Kitamoto ◽  
...  
Keyword(s):  
Visual Field ◽  
Retinitis Pigmentosa ◽  
Fundus Autofluorescence ◽  
Prediction Method ◽  
Field Sensitivity

scholarly journals A Rare Case of Unilateral Retinitis Pigmentosa

2019 ◽  
Vol 2 (1) ◽  
Author(s):  
Syntia Nusanti ◽  
Mohamad Sidik ◽  
Ari Djatikusumo ◽  
Elyas Aditya
Keyword(s):  
Visual Field ◽  
Retinitis Pigmentosa ◽  
Clinical Examination ◽  
Rare Case ◽  
Retinal Pigment ◽  
Multifocal Electroretinogram ◽  
Ophthalmological Examination ◽  
Secondary Causes ◽  
Rule Out

Introduction: Retinitis pigmentosa (RP) is a hereditary disorder that diffusely involve photoreceptor and retinal pigment epithelial (RPE). It is characterized by progressive visual field loss and abnormal ERG. Unilateral RP is a rare condition that is usually sporadic. Clinical presentation and ancillary test results are similar to bilateral RP, with only one eye affected. In making the diagnosis of unilateral RP, clinicians must be able to rule out secondary causes, document a normal ERG in the unaffected eye, and follow-up the patient for at least 5 years to rule out bilateral but asymmetric disease. the aim of this case report is how to diagnose a rare case unilateral RP from clinical examination and ancillary tests. Methods: We report a case of a 33-year-old female with slowly progressive restriction of visual field of the left eye in the last one year before admission. Ophthalmological examination of the left eye revealed bone spicules spreading to peripheral fundus. Visual field examination revealed severely constricted visual field of the left eye. The multifocal electroretinogram (mfERG) examination showed severely depressed ERG function with reduced foveal responses. The fellow eye was within normal limit. Results: Patient was diagnosed with unilateral RP and must be followed-up for at least five years to rule out bilateral yet asymmetric disease. Making diagnosis of unilateral RP become one of the challenging case. Clinicians must be able to rule out the secondary causes that also have unilateral pigmentary retinal degeneration. Conclusion: With a good clinical examination and some simple ancillary tests, we could correctly diagnose unilateral RP. However, in this case we still need five years follow up to rule out bilateral RP yet asymmetric disease.

scholarly journals Regional Relationship between Macular Retinal Thickness and Corresponding Central Visual Field Sensitivity in Glaucoma Patients

2017 ◽  
Vol 2017 ◽  
pp. 1-9 ◽  
Author(s):  
Chun-Hsiu Liu ◽  
Shirley H. L. Chang ◽  
Shiu-Chen Wu
Keyword(s):  
Visual Field ◽  
Retinal Thickness ◽  
Open Angle Glaucoma ◽  
Characteristic Curve ◽  
Correlation Coefficients ◽  
Warning Sign ◽  
Central Visual Field ◽  
Field Sensitivity ◽  
Macular Retinal Thickness ◽  
Sd Oct

Purpose. To investigate the relationship between macular retinal thickness (MRT) and central visual field sensitivity (VFS) in patients with glaucoma.Methods. This retrospective study enrolled patients diagnosed with open-angle glaucoma. All study patients underwent Humphrey 10-2 visual field (VF) test and Spectralis spectral-domain optical coherence tomography (SD-OCT) exam for MRT measurement.Results. Sixty-eight eyes of 68 patients were examined. The correlation coefficients between VFS and MRT were 0.331 (P=0.006) and 0.491 (P=0.000) in the superior and inferior hemispheres, respectively. The average MRT in the eyes with abnormal 10-2 VF hemifields was significantly thinner than that in the eyes without abnormal hemifields in both hemispheres (P=0.005and 0.000 in the superior and inferior hemisphere, resp.). The average MRT values with an optimal sensitivity-specificity balance for discriminating the abnormal VF hemifield from the normal hemifield were 273.5 μm and 255.5 μm in the superior and inferior hemisphere, respectively. The area under the receiver operating characteristic curve was 0.701 in the superior hemisphere and 0.784 in the inferior hemisphere (bothP<0.05).Conclusions. MRT measured through SD-OCT was significantly correlated with central VFS. Lower MRT values might be a warning sign for central VF defects in glaucoma patients.

scholarly journals A Comparison of Visual Field Sensitivity to Photoreceptor Thickness in Retinitis Pigmentosa

2010 ◽  
Vol 51 (8) ◽  
pp. 4213 ◽  
Author(s):  
Nalini V. Rangaswamy ◽  
Hemaxi M. Patel ◽  
Kirsten G. Locke ◽  
Donald C. Hood ◽  
David G. Birch
Keyword(s):  
Visual Field ◽  
Retinitis Pigmentosa ◽  
Field Sensitivity

scholarly journals Ocular Toxoplasmosis Associated with Unilateral Pigmentary Retinopathy That May Mimic Retinitis Pigmentosa: Diagnostic Dilemmas

Medicina ◽  
2021 ◽  
Vol 57 (9) ◽  
pp. 892
Author(s):  
Izabella Karska-Basta ◽  
Bożena Romanowska-Dixon ◽  
Dorota Pojda-Wilczek ◽  
Natalia Mackiewicz
Keyword(s):  
Visual Field ◽  
Retinitis Pigmentosa ◽  
Multifocal Electroretinogram ◽  
Young Male ◽  
Inflammatory Lesion ◽  
Ocular Toxoplasmosis ◽  
Pigmentary Retinopathy ◽  
Polymerase Chain ◽  
The Right ◽  
Chorioretinal Scar

We report a unique case of coexisting pigmentary retinopathy and ocular toxoplasmosis in a young male patient. A 23-year-old man presented with sudden visual deterioration in the left eye (LE). The fundus findings revealed bone spicule-shaped pigment deposits, a slightly pale optic disc, arteriole constriction, cystoid macular edema with an epiretinal membrane, and two small inflammatory chorioretinal scars in the right eye, with a concentric narrowing of the visual field and a nonrecordable multifocal electroretinogram (ERG). An active inflammatory lesion at the border of a pre-existing chorioretinal scar in the macula was found in the LE, with a central scotoma in the visual field. Moreover, the patient tested positive for anti-Toxoplasma gondii immunoglobulin G antibodies and showed positive results in polymerase chain reaction testing of aqueous humor. Fluorescein angiography revealed hyperfluorescence in the early phase with fluorescein leakage. A multifocal ERG of the LE showed selective loss of responses from the central 10 degrees. Genetic testing revealed heterozygosity in the RP1 and CELSR1 genes. Our case illustrates challenges in the diagnosis of unilateral pigmentary retinopathy. Based on the typical toxoplasmic lesions in the LE and two scars likely caused by inflammation, our patient was diagnosed with pigmentary retinopathy probably related to toxoplasmosis. Genetic consultation did not confirm the diagnosis of retinitis pigmentosa, but more advanced tests might be needed to definitively exclude it.

scholarly journals Corneal hysteresis as a risk factor for optic nerve head surface depression and retinal nerve fiber layer thinning in glaucoma patients

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Guihua Xu ◽  
Zilin Chen
Keyword(s):  
Risk Factor ◽  
Visual Field ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Corneal Hysteresis ◽  
Visual Field Progression ◽  
Increased Risk ◽  
Head Surface ◽  
Sd Oct ◽  
Surface Depression

AbstractTo evaluate the role of corneal hysteresis (CH) as a risk factor for progressive ONH surface depression and RNFL thinning measured by confocal scanning laser ophthalmoscopy (CSLO) and spectral-domain optical coherence tomography (SD-OCT), respectively in glaucoma patients. Prospective study. A total of 146 eyes of 90 patients with glaucoma were recruited consecutively. The CH measurements were acquired at baseline and 4-months interval using the Ocular Response Analyzer (Reichert Instruments, Depew, NY). Eyes were imaged by CSLO (Heidelberg Retinal Tomograph [HRT]; Heidelberg Engineering, GmbH, Dossenheim, Germany) and SD-OCT (Cirrus HD-OCT; Carl Zeiss Meditec AG, Dublin, CA) at approximately 4-month intervals for measurement of ONH surface topography and RNFL thickness, respectively. Significant ONH surface depression and RNFL thinning were defined with reference to Topographic Change Analysis (TCA) with HRT and Guided Progression Analysis (GPA) with Cirrus HD-OCT, respectively. Multivariate cox proportional hazards models were used to investigate whether CH is a risk factor for ONH surface depression and RNFL progression after adjusting potential confounding factors. All patients with glaucoma were followed for an average of 6.76 years (range, 4.56–7.61 years). Sixty-five glaucomatous eyes (44.5%) of 49 patients showed ONH surface depression, 55 eyes (37.7%) of 43 patients had progressive RNFL thinning and 20 eyes (13.7%) of 17 patients had visual field progression. In the cox proportional hazards model, after adjusting baseline diastolic IOP, CCT, age, baseline disc area and baseline MD, baseline CH was significantly associated with ONH surface depression and visual field progression (HR = 0.71, P = 0.014 and HR = 0.54, P = 0.018, respectively), but not with RNFL thinning (HR = 1.03, P = 0.836). For each 1-mmHg decrease in baseline CH, the hazards for ONH surface depression increase by 29%, and the hazards for visual field progression increase by 46%. The CH measurements were significantly associated with risk of glaucoma progression. Eyes with a lower CH were significantly associated with an increased risk of ONH surface depression and visual field progression in glaucoma patients.

scholarly journals Concentric division of 10° visual field tests in retinitis pigmentosa

2013 ◽  
Vol 57 (3) ◽  
pp. 268-274 ◽  
Author(s):  
Ken Ogino ◽  
Atsushi Otani ◽  
Akio Oishi ◽  
Masafumi Kurimoto ◽  
Takuro Sekiya ◽  
...  
Keyword(s):  
Visual Field ◽  
Retinitis Pigmentosa ◽  
Field Tests

Regional vascular density–visual field sensitivity relationship in glaucoma according to disease severity

2017 ◽  
Vol 101 (12) ◽  
pp. 1666-1672 ◽  
Author(s):  
Joong Won Shin ◽  
Jiyun Lee ◽  
Junki Kwon ◽  
Jaewan Choi ◽  
Michael S Kook
Keyword(s):  
Visual Field ◽  
Disease Severity ◽  
Vascular Density ◽  
Field Sensitivity
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