scholarly journals Retinal Pathway Origins of the Pattern Electroretinogram (PERG)

2011 ◽  
Vol 52 (12) ◽  
pp. 8571 ◽  
Author(s):  
Xunda Luo ◽  
Laura J. Frishman
Keyword(s):  
Pattern Electroretinogram

scholarly journals The role of pattern electroretinograms and optical coherence tomography angiography in the diagnosis of normal-tension glaucoma

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Sang Yeop Lee ◽  
Nak-Hoon Son ◽  
Hyoung Won Bae ◽  
Gong Je Seong ◽  
Chan Yun Kim
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Early Stage ◽  
Pattern Electroretinogram ◽  
Normal Tension Glaucoma ◽  
Optical Coherence ◽  
Early Glaucoma ◽  
Normal Individuals ◽  
Auc Value ◽  
Glaucoma Group

AbstractIn this study, we investigated the correlation between pattern electroretinogram (PERG) and optical coherence tomography angiography (OCTA) parameters for diagnosis in patients with normal-tension glaucoma (NTG). Forty-nine normal individuals (49 eyes) and 60 patients with NTG (60 eyes) were enrolled. OCTA and PERG parameters, such as macular vessel density (VD) and the amplitude of N35–P50 and P50–N95, were measured. Correlation analyses were performed between the parameters, and the area under the curve (AUC) was used to identify their diagnostic ability for NTG. Macular VD and the amplitude of N35–P50 and P50–N95 showed significant differences between the normal individuals and patients with NTG. Correlation between P50 and N95 amplitude and macular VD was significant in the normal and early glaucoma groups. Macular VD showed a higher AUC value (0.730) than that of P50–N95 amplitude (0.645) in the early glaucoma group. In the moderate to severe glaucoma group, the AUC value of the amplitude of P50–N95 (0.907) was higher than that of macular VD (0.876). The results indicate that PERG and OCTA parameters may identify glaucoma in its early stage, based on the severity of glaucomatous damage in patients with NTG.

scholarly journals Blue light blind-spot stimulation upregulates b-wave and pattern ERG activity in myopes

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Ana Amorim-de-Sousa ◽  
Tim Schilling ◽  
Paulo Fernandes ◽  
Yeshwanth Seshadri ◽  
Hamed Bahmani ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Electrical Activity ◽  
Blue Light ◽  
Optic Nerve Head ◽  
Plexiform Layer ◽  
Pattern Electroretinogram ◽  
Blind Spot ◽  
Inner Plexiform Layer ◽  
Pattern Erg ◽  
Myopia Progression

AbstractUpregulation of retinal dopaminergic activity may be a target treatment for myopia progression. This study aimed to explore the viability of inducing changes in retinal electrical activity with short-wavelength light targeting melanopsin-expressing retinal ganglion cells (ipRGCs) passing through the optic nerve head. Fifteen healthy non-myopic or myopic young adults were recruited and underwent stimulation with blue light using a virtual reality headset device. Amplitudes and implicit times from photopic 3.0 b-wave and pattern electroretinogram (PERG) were measured at baseline and 10 and 20 min after stimulation. Relative changes were compared between non-myopes and myopes. The ERG b-wave amplitude was significantly larger 20 min after blind-spot stimulation compared to baseline (p < 0.001) and 10 min (p < 0.001) post-stimulation. PERG amplitude P50-N95 also showed a significant main effect for ‘Time after stimulation’ (p < 0.050). Implicit times showed no differences following blind-spot stimulation. PERG and b-wave changes after blind-spot stimulation were stronger in myopes than non-myopes. It is possible to induce significant changes in retinal electrical activity by stimulating ipRGCs axons at the optic nerve head with blue light. The results suggest that the changes in retinal electrical activity are located at the inner plexiform layer and are likely to involve the dopaminergic system.

Multifocal Pattern Electroretinogram: Cellular Origins and Clinical Implications

2006 ◽  
Vol 83 (7) ◽  
pp. 473-485 ◽  
Author(s):  
WENDY W. HARRISON ◽  
SURESH VISWANATHAN ◽  
VICTOR E. MALINOVSKY
Keyword(s):  
Pattern Electroretinogram ◽  
Clinical Implications

Spatial Selectivity of Pattern Electroretinogram Components

1990 ◽  
Vol 22 (5) ◽  
pp. 280-286 ◽  
Author(s):  
M. Yoshii ◽  
E. Dodt
Keyword(s):  
Pattern Electroretinogram ◽  
Spatial Selectivity

scholarly journals Pattern Electroretinogram Detects Localized Glaucoma Defects

2018 ◽  
Vol 7 (5) ◽  
pp. 6 ◽  
Author(s):  
Tommaso Salgarello ◽  
Andrea Giudiceandrea ◽  
Luigi Calandriello ◽  
Dario Marangoni ◽  
Alberto Colotto ◽  
...  
Keyword(s):  
Pattern Electroretinogram

Pattern electroretinogram: Use of noncorneal skin electrodes

1985 ◽  
Vol 25 (6) ◽  
pp. 867-870 ◽  
Author(s):  
L.E. Leguire ◽  
G.L. Rogers
Keyword(s):  
Pattern Electroretinogram ◽  
Skin Electrodes

The Pattern Electroretinogram in Glaucoma Patients with Confirmed Visual Field Deficits

2005 ◽  
Vol 46 (7) ◽  
pp. 2411 ◽  
Author(s):  
Donald C. Hood ◽  
Li Xu ◽  
Phamornsak Thienprasiddhi ◽  
Vivienne C. Greenstein ◽  
Jeffrey G. Odel ◽  
...  
Keyword(s):  
Visual Field ◽  
Pattern Electroretinogram ◽  
Visual Field Deficits

Stargardt and Fundus Flavimaculatus; Pathophysiology, Clinical Findings, Imaging Characteristics, and Diagnosis

2021 ◽  
pp. 185-189
Keyword(s):  
Visual Acuity ◽  
Fundus Autofluorescence ◽  
Age At Onset ◽  
Pattern Electroretinogram ◽  
Clinical Findings ◽  
Macular Dystrophy ◽  
Macular Lesion ◽  
Imaging Characteristics ◽  
Wide Variability ◽  
Severity Of The Disease

Stargardt disease (STGD) is the most common form of recessively inherited macular dystrophy. It is characterized by the presence of an atrophic macular lesion, which is surrounded by irregular, white-yellow, deep retinal lesions (flecks). There is wide variability in age at onset, visual acuity, fundus appearance, and severity of the disease. Fundus examination can be normal but visual acuity can be reduced early in the course of the disease. In these patients, pattern electroretinogram (PERG) and fundus autofluorescence (FAF) will be helped in establishing the diagnosis of STGD. The typical sign of “choroidal silence” or dark choroid on fluorescein angiography (FA) is not present in all patients with STGD and is not specific to this condition.

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