Subfoveal Choroidal Thickness in Relation to Sex and Axial Length in 93 Danish University Students

2011 ◽  
Vol 52 (11) ◽  
pp. 8438 ◽  
Author(s):  
Xiao Qiang Li ◽  
Michael Larsen ◽  
Inger Christine Munch
Keyword(s):  
University Students ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Subfoveal Choroidal Thickness

scholarly journals Deep Learning-Based Estimation of Axial Length and Subfoveal Choroidal Thickness From Color Fundus Photographs

2021 ◽  
Vol 9 ◽  
Author(s):  
Li Dong ◽  
Xin Yue Hu ◽  
Yan Ni Yan ◽  
Qi Zhang ◽  
Nan Zhou ◽  
...  
Keyword(s):  
Deep Learning ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Absolute Error ◽  
Population Based ◽  
Fundus Images ◽  
Subfoveal Choroidal Thickness ◽  
Color Fundus Images ◽  
Fundus Photographs ◽  
Map Analysis

This study aimed to develop an automated computer-based algorithm to estimate axial length and subfoveal choroidal thickness (SFCT) based on color fundus photographs. In the population-based Beijing Eye Study 2011, we took fundus photographs and measured SFCT by optical coherence tomography (OCT) and axial length by optical low-coherence reflectometry. Using 6394 color fundus images taken from 3468 participants, we trained and evaluated a deep-learning-based algorithm for estimation of axial length and SFCT. The algorithm had a mean absolute error (MAE) for estimating axial length and SFCT of 0.56 mm [95% confidence interval (CI): 0.53,0.61] and 49.20 μm (95% CI: 45.83,52.54), respectively. Estimated values and measured data showed coefficients of determination of r2 = 0.59 (95% CI: 0.50,0.65) for axial length and r2 = 0.62 (95% CI: 0.57,0.67) for SFCT. Bland–Altman plots revealed a mean difference in axial length and SFCT of −0.16 mm (95% CI: −1.60,1.27 mm) and of −4.40 μm (95% CI, −131.8,122.9 μm), respectively. For the estimation of axial length, heat map analysis showed that signals predominantly from overall of the macular region, the foveal region, and the extrafoveal region were used in the eyes with an axial length of < 22 mm, 22–26 mm, and > 26 mm, respectively. For the estimation of SFCT, the convolutional neural network (CNN) used mostly the central part of the macular region, the fovea or perifovea, independently of the SFCT. Our study shows that deep-learning-based algorithms may be helpful in estimating axial length and SFCT based on conventional color fundus images. They may be a further step in the semiautomatic assessment of the eye.

scholarly journals Changes in Subfoveal Choroidal Thickness and Axial Length in Children Wearing Hyperopic Glasses

2020 ◽  
Vol 49 (0) ◽  
pp. 127-135
Author(s):  
Chihiro Sato ◽  
Miwa Nitta ◽  
Ayaka Kasai ◽  
Takafumi Mori ◽  
Teiko Hashimoto ◽  
...  
Keyword(s):  
Axial Length ◽  
Choroidal Thickness ◽  
Subfoveal Choroidal Thickness

scholarly journals Choroidal Thickness in Chinese Children Aged 8 to 11 Years with Mild and Moderate Myopia

2018 ◽  
Vol 2018 ◽  
pp. 1-7
Author(s):  
Ya Qi ◽  
Li Li ◽  
Fengju Zhang
Keyword(s):  
Refractive Error ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Narrow Range ◽  
The Other ◽  
Chinese Children ◽  
Healthy Children ◽  
Spherical Equivalent ◽  
Subfoveal Choroidal Thickness

Purpose. To investigate macular choroidal thickness (CT), topographical variation, and associations between subfoveal choroidal thickness (SFCT) and age, gender, spherical equivalent (SE), and axial length (AL) in Chinese healthy mild and moderate myopia children aged 8 to 11 years. Methods. One hundred twenty eyes from 120 healthy children were studied. Children were divided into mild and moderate myopia groups. AL and CT were evaluated. CTs were measured at the fovea, and 1 mm, 2 mm, and 3 mm nasal, temporal, superior, and inferior to the fovea. Results. SFCT was 252.80 ± 46.95 µm in the whole population. AL was shorter in the mild myopia group (24.18 ± 0.69 mm) than in the moderate myopia group (24.97 ± 0.68 mm, P<0.001), and SFCT was thicker in the mild myopia group (262.00 ± 40.57 µm) than in the moderate myopia group (236.00 ± 55.08 µm, P=0.005). The topographical variation was similar in refraction groups. CTs nasal to the fovea thinned gradually and were all significantly thinner than SFCT. CTs in the other three directions gradually thickened and peaked at locations of 2 mm to the fovea. Then, CTs thinned at 3 mm to the fovea. The thickest choroid is located temporal to the fovea. There were significant negative correlations between AL and SFCT in the mild myopia group and the whole population. No other correlations were found. Conclusions. The topographical variations of choroidal thickness were similar in mild and moderate myopia groups with the thickest locations temporal to the fovea. SFCT was relatively stable in children in narrow range of age and refractive error.

scholarly journals Axial length and subfoveal choroidal thickness in individuals with age-related macular degeneration

2015 ◽  
Vol 5 (4) ◽  
pp. 169-176 ◽  
Author(s):  
Chih-Ping Wang ◽  
Chien-Hsiung Lai ◽  
Evelyn Jou-Chen Huang ◽  
Pei-Lun Wu ◽  
Ching-Lung Chen ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Age Related Macular Degeneration ◽  
Subfoveal Choroidal Thickness ◽  
Age Related

scholarly journals Changes in Subfoveal Choroidal Thickness of Myopic Children with 0.01% Atropine, Orthokeratology, or their Combination

2021 ◽  
Author(s):  
Qian Hao ◽  
Qi Zhao
Keyword(s):  
Axial Length ◽  
Choroidal Thickness ◽  
Randomized Controlled Study ◽  
Controlled Study ◽  
Myopia Progression ◽  
Subfoveal Choroidal Thickness ◽  
Randomized Controlled

Abstract Purpose: To compare the changes in subfoveal choroidal thickness (SFChT) treated with 0.01% atropine, orthokeratology (OK), or their combination in myopic children, and to study the connection between increase in SFChT and axial length (AL) elongation.Methods: A prospective, randomized, controlled study. A total of 67 children were included; 22 patients were randomly assigned to the SA group (spectacles and 0.01% atropine), 24 patients were randomly assigned to the OK group (OK), and 21 patients were randomly assigned to the OKA group (OK and 0.01% atropine). Comprehensive ophthalmologic examinations were performed at baseline, 1 month, 6 months, and 12 months.Results: After 1 month, SFChT increased by 5.41 ± 1.65 μm in the SA group, 17.46 ± 2.79 μm in the OK group, and 20.19 ± 2.18 μm in the OKA group (P = 0.00), while AL was not significantly increased. After 12 months, the changes of SFChT were not increased significantly compared with that at 1 month; AL increased by 0.20 ± 0.03 mm in the SA group, 0.28 ± 0.03 mm in the OK group, and 0.14 ± 0.03 mm in the OKA group (P = 0.00). The change in SFChT at 12 month was negatively correlated with the change in AL at 12 months.Conclusion: The control of AL elongation was better with 0.01% atropine than with OK lenses. The increase in SFChT was greater with OK lenses and the changes were significant after only 1 month. In addition, the increase in SFChT may influence AL elongation and myopia progression.

scholarly journals Change in subfoveal choroidal thickness secondary to orthokeratology and its cessation: a predictor for the change in axial length

2018 ◽  
Vol 97 (3) ◽  
pp. e454-e459 ◽  
Author(s):  
Zhouyue Li ◽  
Yin Hu ◽  
Dongmei Cui ◽  
Wen Long ◽  
Mingguang He ◽  
...  
Keyword(s):  
Axial Length ◽  
Choroidal Thickness ◽  
Subfoveal Choroidal Thickness

Evaluation of choroidal thickness in amblyopia using optical coherence tomography

2019 ◽  
Vol 30 (4) ◽  
pp. 629-634
Author(s):  
Yi Zha ◽  
Jinfei Zhuang ◽  
Wangqiang Feng ◽  
Haihua Zheng ◽  
Jianqiu Cai
Keyword(s):  
Optical Coherence Tomography ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Significant Negative Correlation ◽  
Analysis Of Covariance ◽  
Optical Coherence ◽  
Subfoveal Choroidal Thickness ◽  
Significant Difference ◽  
And Control ◽  
Fellow Eyes

Objective: To investigate the choroidal thickness in children with amblyopia through spectral-domain optical coherence tomography. Methods: A total of 31 children with unilateral amblyopia and 31 right eyes of controls with normal vision were enrolled in the study. The choroidal thickness was measured directly below the fovea and at 12 other locations: 1, 2 and 3 mm superior, temporal, inferior, and nasal to the fovea. All the parameters were compared between amblyopic eyes, fellow eyes, and control eyes. Results: The mean subfoveal choroidal thickness was 398.03 ± 74.60, 354.13 ± 81.78, and 328.12 ± 65.93 μm in amblyopic eyes, fellow eyes, and control eyes, respectively. Significant difference was found in choroidal thickness among three groups at subfoveal choroidal thickness, N1, and S1 using multivariate analysis of covariance after adjusting for axial length. Significant negative correlation was found only between subfoveal choroidal thickness and axial length in amblyopic eyes (r = –0.463, p = 0.01). Conclusion: The subfoveal choroid is significantly thicker in amblyopic eyes than control eyes only at subfoveal choroidal thickness, N1, and S1. The choroidal thickness was thickest in the subfoveal region and thinnest in the nasal region. There are other changes in choroidal structure associated with amblyopia.

Choroidal Thickness and Ametropia in Children: A Longitudinal Study

2017 ◽  
Vol 27 (6) ◽  
pp. 730-734 ◽  
Author(s):  
Marine Fontaine ◽  
David Gaucher ◽  
Arnaud Sauer ◽  
Claude Speeg-Schatz
Keyword(s):  
Longitudinal Study ◽  
Axial Length ◽  
Choroidal Thickness ◽  
Subfoveal Choroidal Thickness ◽  
Relationship Of ◽  
The Relationship

Purpose To determine the relationship of subfoveal choroidal thickness (ChT), refraction, and axial length in children, and evaluate the evolution of subfoveal ChT with time in myopic versus nonmyopic eyes. Methods A total of 229 eyes of 115 children aged 2 to 16 years were included in the study. Refraction under cycloplegia, axial length, and subfoveal ChT were measured at baseline with comparative investigations at 15 months follow-up. Results The probability for the subfoveal ChT to be thinner in myopic children compared to nonmyopic children was 0.9999. We found a relation between subfoveal ChT and axial length. At 15 months follow-up, subfoveal ChT was found to have increased in the nonmyopic eyes, but decreased in myopic patients. Conclusions A number of studies have already shown the choroid to play an important role in the process of emmetropization. We found that ChT had a different evolution in myopic children compared to nonmyopic children. A thinner choroid may predict the onset, or progression, of myopia. Further studies, with longer follow-up, are necessary to confirm this hypothesis.

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