The Anti-oxidative Role of ABCG2 in Corneal Epithelial Cells

2010 ◽  
Vol 51 (11) ◽  
pp. 5617 ◽  
Author(s):  
Miyuki Kubota ◽  
Shigeto Shimmura ◽  
Hideyuki Miyashita ◽  
Motoko Kawashima ◽  
Tetsuya Kawakita ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Corneal Epithelial Cells ◽  
Corneal Epithelial

Role of TREM-1 in response to Aspergillus fumigatus infection in corneal epithelial cells

2014 ◽  
Vol 23 (1) ◽  
pp. 288-293 ◽  
Author(s):  
Li-ting Hu ◽  
Zhao-dong Du ◽  
Gui-qiu Zhao ◽  
Nan Jiang ◽  
Jing Lin ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Aspergillus Fumigatus ◽  
Corneal Epithelial Cells ◽  
Corneal Epithelial

Role of the Mannose Receptor During Aspergillus fumigatus Infection and Interaction With Dectin-1 in Corneal Epithelial Cells

Cornea ◽  
2016 ◽  
Vol 35 (2) ◽  
pp. 267-273 ◽  
Author(s):  
Qian Wang ◽  
Guiqiu Zhao ◽  
Jing Lin ◽  
Cui Li ◽  
Nan Jiang ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Aspergillus Fumigatus ◽  
Mannose Receptor ◽  
Corneal Epithelial Cells ◽  
Corneal Epithelial

scholarly journals Atropine Differentially Modulates ECM Production by Ocular Fibroblasts, and Its Ocular Surface Toxicity Is Blunted by Colostrum

Biomedicines ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 78
Author(s):  
Martina Cristaldi ◽  
Melania Olivieri ◽  
Salvatore Pezzino ◽  
Giorgia Spampinato ◽  
Gabriella Lupo ◽  
...  
Keyword(s):  
Epithelial Cells ◽  
Test Results ◽  
Corneal Epithelial Cells ◽  
Corneal Epithelial ◽  
Atropine Treatment ◽  
Progressive Myopia ◽  
Methyl Xanthine

Background: The etiology and the mechanism behind atropine treatment of progressive myopia are still poorly understood. Our study addressed the role of scleral and choroidal fibroblasts in myopia development and atropine function. Methods: Fibroblasts treated in vitro with atropine or 7-methylxanthine were tested for ECM production by Western blotting. Corneal epithelial cells were treated with atropine in the presence or absence of colostrum or fucosyl-lactose, and cell survival was evaluated by the MTT metabolic test. Results: Atropine and 7-methyl-xanthine stimulated collagen I and fibronectin production in scleral fibroblasts, while they inhibited their production in choroidal fibroblasts. Four days of treatment with atropine of corneal epithelial cells significantly decreased cell viability, which could be prevented by the presence of colostrum or fucosyl-lactose. Conclusions: Our results show that atropine may function in different ways in different eye districts, strengthening the scleral ECM and increasing permeability in the choroid. The finding that colostrum or fucosyl-lactose attenuate the corneal epithelial toxicity after long-term atropine treatment suggests the possibility that both compounds can efficiently blunt its toxicity in children subjected to chronic atropine treatment.

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