scholarly journals Molecular and Biochemical Characterization of Folate Transport Proteins in Retinal Müller Cells

2010 ◽  
Vol 51 (6) ◽  
pp. 3226 ◽  
Author(s):  
B. Renee Bozard ◽  
Preethi S. Ganapathy ◽  
Jennifer Duplantier ◽  
Barbara Mysona ◽  
Yonju Ha ◽  
...  
Keyword(s):  
Biochemical Characterization ◽  
Müller Cells ◽  
Transport Proteins ◽  
Muller Cells ◽  
Folate Transport ◽  
Folate Transport Proteins

Decreased expression of folate transport proteins in oral cancer

2019 ◽  
Vol 127 (5) ◽  
pp. 417-424
Author(s):  
Joanna Goral ◽  
Kayla Cuadros ◽  
Lenore Pitstick ◽  
Alice Meyer ◽  
Bruno Correia Jham ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Transport Proteins ◽  
Folate Transport ◽  
Folate Transport Proteins

Affinity labeling of folate transport proteins with the N-hydroxysuccinimide ester of .gamma.-isomer of fluorescein-methotrexate

Biochemistry ◽  
1991 ◽  
Vol 30 (18) ◽  
pp. 4573-4580 ◽  
Author(s):  
Jianguo Fan ◽  
Laura E. Pope ◽  
Karin S. Vitols ◽  
F. M. Huennekens
Keyword(s):  
Transport Proteins ◽  
Affinity Labeling ◽  
Folate Transport ◽  
Folate Transport Proteins

scholarly journals Effect of Adenosine and Adenosine Receptor Antagonists on Retinal Müller Cell Inwardly Rectifying Potassium Channels under Exogenous Glutamate Stimulation

2018 ◽  
Vol 2018 ◽  
pp. 1-10
Author(s):  
Zhongjing Lin ◽  
Ping Huang ◽  
Shouyue Huang ◽  
Lei Guo ◽  
Xing Xu ◽  
...  
Keyword(s):  
Müller Cells ◽  
Muller Cells ◽  
Digestion Method ◽  
Expression Levels ◽  
Inwardly Rectifying Potassium Channels ◽  
Dose Dependent Decrease ◽  
Inwardly Rectifying ◽  
Dose Dependent ◽  
Papain Digestion

The vitreousness of glaucoma subjects contains elevated glutamate, and excessive extracellular glutamate is toxic to retinal neurons. Therefore, glutamate clearance is potentially impaired in the retina of glaucoma subjects. Müller cells play an important role in maintaining low extracellular levels of neurotransmitters, such as glutamate. A better understanding of the cross-talk between adenosine and glutamate may provide a better characterization of the regulatory network in Müller cells. Here, Müller cells were purified from the rat retina on postnatal day 5 using the papain digestion method. Application of increasing concentrations of glutamate (0-20 mmol/L) caused a dose-dependent decrease in the expression levels of Kir4.1, Kir2.1, GLAST, and GS. Exogenous adenosine regulated Kir channels and subsequently promoted GLAST and GS expression levels in Müller cells under exogenous glutamate stimulation. These effects were partly dependent on adenosine receptors.

Visualization of membrane-associated folate transport proteins

1989 ◽  
Vol 28 ◽  
pp. 3-11 ◽  
Author(s):  
L.E. Pope ◽  
J. Fan ◽  
C.-M. Chang ◽  
S.A. Minskoff ◽  
K.S. Vitols ◽  
...  
Keyword(s):  
Transport Proteins ◽  
Folate Transport ◽  
Folate Transport Proteins

scholarly journals Expression of Folate Transport Proteins in a Mouse Model of 4NQO‐Induced Oral Cancer

2019 ◽  
Vol 33 (S1) ◽  
Author(s):  
Jacalyn M Green ◽  
Atmiya Sheth ◽  
Lenore D Pitstick ◽  
Joanna Goral ◽  
Mae Ciancio ◽  
...  
Keyword(s):  
Oral Cancer ◽  
Mouse Model ◽  
Transport Proteins ◽  
Folate Transport ◽  
Folate Transport Proteins
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