Influence of Corneal Collagen Crosslinking with Riboflavin and Ultraviolet-A Irradiation on Excimer Laser Surgery

2010 ◽  
Vol 51 (8) ◽  
pp. 3929 ◽  
Author(s):  
Daniel Kampik ◽  
Bernhard Ralla ◽  
Sabine Keller ◽  
Markus Hirschberg ◽  
Peter Friedl ◽  
...  
Keyword(s):  
Excimer Laser ◽  
Laser Surgery ◽  
Ultraviolet A ◽  
Collagen Crosslinking ◽  
Corneal Collagen Crosslinking ◽  
Corneal Collagen

scholarly journals Outcome of Corneal Collagen Crosslinking for Progressive Keratoconus in Paediatric Patients

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Deepa Viswanathan ◽  
Nikhil L. Kumar ◽  
John J. Males
Keyword(s):  
Young Patients ◽  
Ultraviolet A ◽  
Effective Treatment Option ◽  
Collagen Crosslinking ◽  
Paediatric Patients ◽  
Corneal Grafting ◽  
Minimum Angle ◽  
Corneal Collagen Crosslinking ◽  
The Mean ◽  
Corneal Collagen

Purpose. To evaluate the efficacy of corneal collagen crosslinking for progressive keratoconus in paediatric patients.Methods. This prospective study included 25 eyes of 18 patients (aged 18 years or younger) who underwent collagen crosslinking performed using riboflavin and ultraviolet-A irradiation (370 nm, 3 mW/cm2, 30 min).Results. The mean patient age was 14.3 ± 2.4 years (range 8–17) and mean followup duration was 20.1 ± 14.25 months (range 6–48). Crosslinked eyes demonstrated a significant reduction of keratometry values. The mean baseline simulated keratometry values were 46.34 dioptres (D) in the flattest meridian and 50.06 D in the steepest meridian. At 20 months after crosslinking, the values were 45.67 D (P=0.03) and 49.34 D (P=0.005), respectively. The best spectacle corrected visual acuity (BSCVA) and topometric astigmatism improved after crosslinking. Mean logarithm of the minimum angle of resolution (logMAR) BSCVA decreased from 0.24 to 0.21 (P=0.89) and topometric astigmatism reduced from mean 3.50 D to 3.25 D (P=0.51).Conclusions. Collagen crosslinking using riboflavin and ultraviolet-A is an effective treatment option for progressive keratoconus in paediatric patients. Crosslinking stabilises the condition and, thus, reduces the need for corneal grafting in these young patients.

scholarly journals EFFICACY OF CORNEAL COLLAGEN CROSSLINKING WITH RIBOFLAVIN AND ULTRAVIOLET-A IN PROGRESSIVE KERATOCONUS.

2020 ◽  
pp. 1-3
Author(s):  
Priyanka Raut ◽  
Nikhilesh * Wairagade ◽  
Praneeta Sakarkar
Keyword(s):  
P Value ◽  
Spherical Equivalent ◽  
Ultraviolet A ◽  
Collagen Crosslinking ◽  
Institutional Ethics ◽  
Uncorrected Visual Acuity ◽  
Corneal Collagen Crosslinking ◽  
The Mean ◽  
A Prospective Study ◽  
Corneal Collagen

PURPOSE-To evaluate outcomes of collagen crosslinking in patients having progressive keratoconus. METHODS- A prospective study was done in eyes that underwent corneal collagen crosslinking for treatment of progressive keratoconus. This study was performed after approval from Institutional Ethics Committee and informed consent was obtained from all the patients. Data was analysed with the help of JASP0.8.3.1 and MS-Excel 2013. RESULT-The mean age was 20.94 ± 2.04 years. 21 (63.63%) were males, 12 (36.36 %) were females. The mean uncorrected visual acuity (UCVA) pre-operative and post-operative at 6 months were 0.64 ± 0.37 and 0.53 ± 0.31 (logMAR) respectively (p value 0.03). Mean spherical equivalent pre-operatively and post-operatively at 6 months were -2.85 ± 2.14 and -2.38 ± 1.70 respectively (p < 0.001). Mean keratometry (Mean K) preoperative and post-operative were 49.85 ± 4.10 Dioptres (D) and 49.22 ± 4.09 D respectively (p = 0.0007). CONCLUSION- Corneal collagen crosslinking with UV-A and riboavin is a safe and effective method for halting the deterioration of progressive keratoconus.

Intraocular pressure measurements after corneal collagen crosslinking with riboflavin and ultraviolet A in eyes with keratoconus

2010 ◽  
Vol 36 (10) ◽  
pp. 1724-1727 ◽  
Author(s):  
George D. Kymionis ◽  
Michael A. Grentzelos ◽  
George A. Kounis ◽  
Dimitra M. Portaliou ◽  
Efstathios T. Detorakis ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Pressure Measurements ◽  
Ultraviolet A ◽  
Collagen Crosslinking ◽  
Corneal Collagen Crosslinking ◽  
Corneal Collagen

scholarly journals Extensive Corneal Neovascularisation Treatment by Ultraviolet Corneal Collagen Crosslinking

2017 ◽  
Vol 11 (01) ◽  
pp. 62
Author(s):  
Mohammad M Shehadeh ◽  
Mohammad T Akkawi ◽  
Vasilios F Diakonis ◽  
Ammar A Aghbar ◽  
Abdelraheem Abu Shanab ◽  
...  
Keyword(s):  
Case Report ◽  
Dramatic Improvement ◽  
Ultraviolet A ◽  
Collagen Crosslinking ◽  
Topical Antibiotics ◽  
Full Resolution ◽  
Corneal Collagen Crosslinking ◽  
Corneal Collagen

The purpose of this article is to report a case of extensive corneal neovascularisation that was treated by ultraviolet corneal collagen crosslinking (CXL). The case report is about a 24-year-old man who was referred to the cornea clinic with a case of keratitis. He was treated with topical antibiotics. After full resolution of keratitis, his condition was complicated by extensive corneal neovascularisation. A trial of photochemical corneal collagen CXL with riboflavin/ultraviolet A resulted in a dramatic improvement and resolution of the corneal neovascularisation. Thus, we can conclude that corneal collagen CXL could be a promising procedure to treat certain cases of extensive corneal neovascularisation.

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