Elevated Intraocular Pressure, Optic Nerve Atrophy, and Impaired Retinal Development in ODAG Transgenic Mice

2009 ◽  
Vol 50 (1) ◽  
pp. 242 ◽  
Author(s):  
Takaaki Sasaki ◽  
Wataru Watanabe ◽  
Yuki Muranishi ◽  
Takashi Kanamoto ◽  
Makoto Aihara ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Transgenic Mice ◽  
Retinal Development ◽  
Optic Nerve Atrophy ◽  
Elevated Intraocular Pressure

scholarly journals Optic Nerve Head Astrocytes Display Axon-Dependent and -Independent Reactivity in Response to Acutely Elevated Intraocular Pressure

2019 ◽  
Vol 60 (1) ◽  
pp. 312 ◽  
Author(s):  
Shandiz Tehrani ◽  
Lauren Davis ◽  
William O. Cepurna ◽  
R. Katherine Delf ◽  
Diana C. Lozano ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Elevated Intraocular Pressure

Measuring the Biaxial Stress-Strain Characteristics of Human Sclera

2007 ◽  
Author(s):  
C. G. Olesen ◽  
I. Tertinegg ◽  
A. Eilaghi ◽  
G. W. Brodland ◽  
C. Horst ◽  
...  
Keyword(s):  
Risk Factor ◽  
Intraocular Pressure ◽  
Optic Nerve ◽  
Ganglion Cell ◽  
Mechanical Strain ◽  
Biaxial Stress ◽  
Retinal Ganglion ◽  
Irreversible Loss ◽  
Elevated Intraocular Pressure ◽  
Primary Risk Factor

Glaucoma is a common ocular disease that causes irreversible loss of vision. Elevated intraocular pressure (IOP) is the primary risk factor for developing glaucoma. It is believed that increased IOP causes mechanical strain on the glial cells that support the retinal ganglion cell axons and thereby causes ganglion cell apoptosis [1,2]. This damage occurs in the optic nerve head (ONH) region of the eye, and is important for understanding ONH biomechanics.

A case of optic nerve atrophy with excavation, but no increase in intraocular pressure

1930 ◽  
Vol 26 (9) ◽  
pp. 942-942
Author(s):  
J. Meyer
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Normal Pressure ◽  
Optic Nerve Atrophy ◽  
Reduced Pressure

Abstracts. Ophthalmology. J. Meyer (Arch, d'ophtalmolog., 1928) describes a case of optic nerve atrophy with excavation, but without an increase in intraocular pressure in an old man of 60 years. The author does not consider it possible to diagnose glaucoma in this case, but believes that the excavation of the nipple at normal pressure depends on the reduced pressure in the arterial vessels of the retina.

scholarly journals Optic Nerve Traction During Adduction in Open Angle Glaucoma with Normal versus Elevated Intraocular Pressure

2019 ◽  
Vol 45 (2) ◽  
pp. 199-210 ◽  
Author(s):  
Joseph L. Demer ◽  
Robert A. Clark ◽  
Soh Youn Suh ◽  
Joann A. Giaconi ◽  
Kouros Nouri-Mahdavi ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Open Angle Glaucoma ◽  
Open Angle ◽  
Elevated Intraocular Pressure

scholarly journals Astrocyte Structural and Molecular Response to Elevated Intraocular Pressure Occurs Rapidly and Precedes Axonal Tubulin Rearrangement within the Optic Nerve Head in a Rat Model

PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0167364 ◽  
Author(s):  
Shandiz Tehrani ◽  
Lauren Davis ◽  
William O. Cepurna ◽  
Tiffany E. Choe ◽  
Diana C. Lozano ◽  
...  
Keyword(s):  
Intraocular Pressure ◽  
Optic Nerve ◽  
Optic Nerve Head ◽  
Rat Model ◽  
Molecular Response ◽  
Elevated Intraocular Pressure
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