Hyperhomocysteinemia and Low Methionine Stress Are Risk Factors for Central Retinal Venous Occlusion in an Indian Population

2007 ◽  
Vol 48 (4) ◽  
pp. 1441 ◽  
Author(s):  
Angayarkanni Narayanasamy ◽  
Barathi Subramaniam ◽  
Coral Karunakaran ◽  
Punitham Ranganathan ◽  
Ramakrishnan Sivaramakrishnan ◽  
...  
2016 ◽  
Author(s):  
Swati Waghdhare ◽  
Neelam Kaushal ◽  
Rajinder K Jalali ◽  
Divya Vohora ◽  
Sujeet Jha

2013 ◽  
Vol 57 (6) ◽  
pp. 569 ◽  
Author(s):  
Smita Prakash ◽  
Amitabh Kumar ◽  
Shyam Bhandari ◽  
Parul Mullick ◽  
AnoopRaj Gogia ◽  
...  

BMJ Open ◽  
2014 ◽  
Vol 4 (12) ◽  
pp. e005346 ◽  
Author(s):  
T Sekhri ◽  
R S Kanwar ◽  
R Wilfred ◽  
P Chugh ◽  
M Chhillar ◽  
...  

2017 ◽  
Vol 65 (2) ◽  
pp. 279 ◽  
Author(s):  
Subhash Kaul ◽  
Suvarna Alladi ◽  
KRukmini Mridula ◽  
V C SSrinivasarao Bandaru ◽  
Matapathi Umamashesh ◽  
...  

2019 ◽  
Vol 7 (3) ◽  
pp. 446-449 ◽  
Author(s):  
Tarun Goyal ◽  
Anant Singh ◽  
Rahul Sharma ◽  
Arghya Kundu Choudhury ◽  
Shobha S. Arora

2017 ◽  
Vol 7 (2) ◽  
pp. 257-273 ◽  
Author(s):  
Suman Kushwaha ◽  
Puneet Talwar ◽  
Aldrin Anthony ◽  
Meena Gupta ◽  
Kiran Bala ◽  
...  

Background: As variability in the clinical profile of dementia subtypes had been reported with regional differences across the world, we conducted a retrospective hospital-based study in a North Indian population. Methods: We retrieved patient records from 2007 to 2014 for details of clinical evaluation, diagnosis, neuroimaging, biochemical investigations, and follow-up of 1,876 patients with dementia (PwD), and the data were analyzed using descriptive statistics. Results: Of the total PwD, Alzheimer disease (AD) accounted for 30% followed by vascular dementia (VaD) 26%, mixed dementia (MD) 21%, Parkinson-related dementia 11%, frontotemporal dementia (FTD) 7%, and infective dementia 5%. Of all PwD excluding the infective group (n = 1,777), 63% were men, 39% were from rural areas, 87% had behavioral abnormalities along with cognitive deficits, and 73% had impaired ADLs. Among dementia subtypes, a positive family history, cardiovascular and metabolic risk factors, and behavioral abnormalities were found to be distributed. However, there existed a predominance of specific behavioral pattern in each subtype. The mean duration of follow-up varied from 2.9 ± 2.3 (VaD) to 3.6 ± 2.1 (AD) and greater than 30% were found to be stable on treatment (except in dementia with Lewy body). Conclusions: This large hospital-based study provides a distribution pattern and clinical spectrum of dementia subtypes in a North Indian population.


EP Europace ◽  
2019 ◽  
Author(s):  
Anna Polewczyk ◽  
Christopher A Rinaldi ◽  
Manav Sohal ◽  
Pier-Giorgio Golzio ◽  
Simon Claridge ◽  
...  

Abstract Aims Female sex is considered an independent risk factor of transvenous leads extraction (TLE) procedure. The aim of the study was to evaluate the effectiveness of TLE in women compared with men. Methods and results A post hoc analysis of risk factors and effectiveness of TLE in women and men included in the ESC-EHRA EORP ELECTRa registry was conducted. The rate of major complications was 1.96% in women vs. 0.71% in men; P = 0.0025. The number of leads was higher in men (mean 1.89 vs. 1.71; P < 0.0001) with higher number of abandoned leads in women (46.04% vs. 34.82%; P < 0.0001). Risk factors of TLE differed between the sexes, of which the major were: signs and symptoms of venous occlusion [odds ratio (OR) 3.730, confidence interval (CI) 1.401–9.934; P = 0.0084], cumulative leads dwell time (OR 1.044, CI 1.024–1.065; P < 0.001), number of generator replacements (OR 1.029, CI 1.005–1.054; P = 0.0184) in females and the number of leads (OR 6.053, CI 2.422–15.129; P = 0.0001), use of powered sheaths (OR 2.742, CI 1.404–5.355; P = 0.0031), and white blood cell count (OR 1.138, CI 1.069–1.212; P < 0.001) in males. Individual radiological and clinical success of TLE was 96.29% and 98.14% in women compared with 98.03% and 99.21% in men (P = 0.0046 and 0.0098). Conclusion The efficacy of TLE was lower in females than males, with a higher rate of periprocedural major complications. The reasons for this difference are probably related to disparities in risk factors in women, including more pronounced leads adherence to the walls of the veins and myocardium. Lead management may be key to the effectiveness of TLE in females.


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