scholarly journals Habituation of Retinal Ganglion Cell Activity in Response to Steady State Pattern Visual Stimuli in Normal Subjects

2005 ◽  
Vol 46 (4) ◽  
pp. 1296 ◽  
Author(s):  
Vittorio Porciatti ◽  
Nancy Sorokac ◽  
William Buchser
Keyword(s):  
Steady State ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Visual Stimuli ◽  
Cell Activity ◽  
Normal Subjects ◽  
Retinal Ganglion

Intrinsically Photosensitive Retinal Ganglion Cell Activity Is Associated with Decreased Sleep Quality in Patients with Glaucoma

Ophthalmology ◽  
2015 ◽  
Vol 122 (6) ◽  
pp. 1139-1148 ◽  
Author(s):  
Carolina P.B. Gracitelli ◽  
Gloria Liliana Duque-Chica ◽  
Marina Roizenblatt ◽  
Ana Laura de Araújo Moura ◽  
Balazs V. Nagy ◽  
...  
Keyword(s):  
Sleep Quality ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Activity ◽  
Retinal Ganglion

scholarly journals Optogenetic restoration of retinal ganglion cell activity in the living primate

2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Juliette E. McGregor ◽  
Tyler Godat ◽  
Kamal R. Dhakal ◽  
Keith Parkins ◽  
Jennifer M. Strazzeri ◽  
...  
Keyword(s):  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Activity ◽  
Retinal Ganglion

A method for the study of retinal ganglion cell activity induced by ELF magnetic fields

Radio Science ◽  
1979 ◽  
Vol 14 (6S) ◽  
pp. 125-126 ◽  
Author(s):  
P. Lövsund ◽  
P. Å. Öberg ◽  
S. E. G. Nilsson
Keyword(s):  
Magnetic Fields ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Cell Activity ◽  
Retinal Ganglion

scholarly journals Retinal ganglion cell defects cause decision shifts in visually evoked defense responses

2020 ◽  
Vol 124 (5) ◽  
pp. 1530-1549
Author(s):  
Rebecca Nicole Lees ◽  
Armaan Fazal Akbar ◽  
Tudor Constantin Badea
Keyword(s):  
Ganglion Cell ◽  
Brain Stem ◽  
Retinal Ganglion Cell ◽  
Genetically Modified ◽  
Visual Stimuli ◽  
Defense Responses ◽  
Retinal Ganglion ◽  
Freezing Response ◽  
Response Choices ◽  
The Brain

Flight and freezing response choices evoked by visual stimuli are controlled by brain stem and thalamic circuits. Genetically modified mice with loss of specific retinal ganglion cell (RGC) subpopulations have altered flight versus freezing choices in response to some but not other visual stimuli. This finding suggests that “threatening” visual stimuli may be computed already at the level of the retina and communicated via dedicated pathways (RGCs) to the brain.

Retinal Ganglion Cell Axon Regeneration Requires Complement and Myeloid Cell Activity within the Optic Nerve

2021 ◽  
pp. JN-RM-0555-21
Author(s):  
Sheri L. Peterson ◽  
Yiqing Li ◽  
Christina J. Sun ◽  
Kimberly A. Wong ◽  
Kylie S. Leung ◽  
...  
Keyword(s):  
Optic Nerve ◽  
Ganglion Cell ◽  
Retinal Ganglion Cell ◽  
Axon Regeneration ◽  
Cell Activity ◽  
Myeloid Cell ◽  
Retinal Ganglion ◽  
Retinal Ganglion Cell Axon ◽  
Cell Axon ◽  
Ganglion Cell Axon

scholarly journals Multiple fates of newly synthesized neurofilament proteins: evidence for a stationary neurofilament network distributed nonuniformly along axons of retinal ganglion cell neurons.

1986 ◽  
Vol 102 (2) ◽  
pp. 647-659 ◽  
Author(s):  
R A Nixon ◽  
K B Logvinenko
Keyword(s):  
Steady State ◽  
Ganglion Cell ◽  
Distribution Pattern ◽  
Retinal Ganglion Cell ◽  
Axoplasmic Transport ◽  
Retinal Ganglion ◽  
Neurofilament Proteins ◽  
Electron Microscopic ◽  
Stationary Structure ◽  
Biochemical Analyses

We have studied the fate of neurofilament proteins (NFPs) in mouse retinal ganglion cell (RGC) neurons from 1 to 180 d after synthesis and examined the proximal-to-distal distribution of the newly synthesized 70-, 140-, and 200-kD subunits along RGC axons relative to the distribution of neurofilaments. Improved methodology for intravitreal delivery of [3H]proline enabled us to quantitate changes in the accumulation and subsequent decline of radiolabeled NFP subunits at various postinjection intervals and, for the first time, to estimate the steady state levels of NFPs in different pools within axons. Two pools of newly synthesized triplet NFPs were distinguished based on their kinetics of disappearance from a 9-mm "axonal window" comprising the optic nerve and tract and their temporal-spatial distribution pattern along axons. The first pool disappeared exponentially between 17 and 45 d after injection with a half-life of 20 d. Its radiolabeled wavefront advanced along axons at 0.5-0.7 mm/d before reaching the distal end of the axonal window at 17 d, indicating that this loss represented the exit of neurofilament proteins composing the slowest phase of axoplasmic transport (SCa or group V) from axons. About 32% of the total pool of radiolabeled neurofilament proteins, however, remained in axons after 45 d and disappeared exponentially at a much slower rate (t 1/2 = 55 d). This second NFP pool assumed a nonuniform distribution along axons that was characterized proximally to distally by a 2.5-fold gradient of increasing radioactivity. This distribution pattern did not change between 45 and 180 d indicating that neurofilament proteins in the second pool constitute a relatively stationary structure in axons. Based on the relative radioactivities and residence time (or turnover) of each neurofilament pool in axons, we estimate that, in the steady state, more neurofilament proteins in mouse RGC axons may be stationary than are undergoing continuous slow axoplasmic transport. This conclusion was supported by biochemical analyses of total NFP content and by electron microscopic morphometric studies of neurofilament distribution along RGC axons. The 70-, 140-, and 200-kD subunits displayed a 2.5-fold proximal to distal gradient of increasing content along RGC axons. Neurofilaments were more numerous at distal axonal levels, paralleling the increased content of NFP.(ABSTRACT TRUNCATED AT 400 WORDS)

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