Fundus Autofluorescence and Fundus Perimetry in the Junctional Zone of Geographic Atrophy in Patients with Age-Related Macular Degeneration

2004 ◽  
Vol 45 (12) ◽  
pp. 4470 ◽  
Author(s):  
Steffen Schmitz-Valckenberg ◽  
Stefan Bu¨ltmann ◽  
Jens Dreyhaupt ◽  
Almut Bindewald ◽  
Frank G. Holz ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Junctional Zone ◽  
Age Related

Fundus autofluorescence and microperimetry in progressing geographic atrophy secondary to age-related macular degeneration

2013 ◽  
Vol 97 (5) ◽  
pp. 622-626 ◽  
Author(s):  
Elisabetta Pilotto ◽  
Francesca Guidolin ◽  
Enrica Convento ◽  
Luigi Spedicato ◽  
Stela Vujosevic ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Age Related

Progression of Geographic Atrophy and Impact of Fundus Autofluorescence Patterns in Age-related Macular Degeneration

2007 ◽  
Vol 143 (3) ◽  
pp. 463-472.e2 ◽  
Author(s):  
Frank G. Holz ◽  
Almut Bindewald-Wittich ◽  
Monika Fleckenstein ◽  
Jens Dreyhaupt ◽  
Hendrik P.N. Scholl ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Age Related

scholarly journals Percentage of Foveal versus Total Macular Geographic Atrophy as a Predictor of Visual Acuity in Age-related Macular Degeneration

2019 ◽  
Author(s):  
Saghar Bagheri ◽  
Ines Lains ◽  
Rebecca Silverman ◽  
Ivana Kim ◽  
Dean Eliott ◽  
...  
Keyword(s):  
Visual Acuity ◽  
Macular Degeneration ◽  
Fundus Autofluorescence ◽  
Cross Sectional Study ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Cross Sectional ◽  
Age Related ◽  
The Impact ◽  
Foveal Sparing

AbstractObjectivesTo investigate the relationship between visual acuity (VA), total area of geographic atrophy (GA) and percentage of foveal GA.MethodsMulticenter, retrospective cross-sectional study of patients with GA due to age-related macular degeneration. Demographics, VA, fundus autofluorescence (FAF) and optical coherence tomography (OCT) images were collected. Using FAF images aided by OCT, foveal sparing status, GA pattern, total GA size, and percentage of GA covering the foveal area - area within a 1.5 mm diameter circle centered on the fovea centralis - were assessed. Univariable and multiple linear regression analyses were performed.Results54 eyes (mean age 78.7 ±7.7 (SD), 60.0% female) were studied. Mean VA was 0.8 ± 0.6 logMAR, mean total GA 8.8 ± 6.7 mm2 and mean percentage of foveal GA was 71.5 ± 30.9%. Of all assessed eyes, 48.2% (n = 26) presented with multifocal GA, and 18.5% (n = 10) had foveal sparing. Multiple regression analysis revealed that, controlling for age and GA pattern, the percentage of foveal GA presented a statistically significant association with VA (ß = 0.41, P = 0.004). No significant associations were observed with mean total GA size, while controlling for the same variables (ß = 0.010, P = 0.440).ConclusionPercentage of foveal GA was significantly associated with VA impairment, while the same was not verified for total GA area. These findings suggest that percentage of foveal GA may represent a more useful tool for assessing the impact of GA on VA. Further validation is needed in larger cohorts.

scholarly journals Increased Fundus Autofluorescence and Progression of Geographic Atrophy Secondary to Age-Related Macular Degeneration: The GAIN Study

2015 ◽  
Vol 160 (2) ◽  
pp. 345-353.e5 ◽  
Author(s):  
Marc Biarnés ◽  
Luis Arias ◽  
Jordi Alonso ◽  
Míriam Garcia ◽  
Míriam Hijano ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Fundus Autofluorescence ◽  
Geographic Atrophy ◽  
Age Related Macular Degeneration ◽  
Age Related
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