Risk Factors Associated with the Incidence of Open-Angle Glaucoma: The Visual Impairment Project

2003 ◽  
Vol 44 (9) ◽  
pp. 3783 ◽  
Author(s):  
Anhchuong Le ◽  
Bickol N. Mukesh ◽  
Catherine A. McCarty ◽  
Hugh R. Taylor
2016 ◽  
Vol 16 (1) ◽  
Author(s):  
Fatima Kyari ◽  
◽  
Mohammed M. Abdull ◽  
Richard Wormald ◽  
Jennifer R. Evans ◽  
...  

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Jihei Sara Lee ◽  
Gong Je Seong ◽  
Chan Yun Kim ◽  
Sang Yeop Lee ◽  
Hyoung Won Bae

AbstractThe purpose of this study was to identify risk factors associated with progressive retinal nerve fiber layer(RNFL) thinning of open-angle glaucoma(OAG) in patients whose intraocular pressure(IOP) was maintained low with medical treatment. Based on a retrospective review of medical records, OAG patients with ≥60 months of follow-up and mean IOP below 15 mmHg were recruited. All eyes underwent IOP measurement with Goldmann applanation tonometer(GAT), standard automated perimetry(SAP), and cirrus optical coherence tomography(cirrus OCT) at 6 month or 1 year intervals. RNFL thinning was assessed using the Guided Progression Analysis(GPA) software. Forty-one eyes of 41 patients (mean age 54.9 ± 13.5) were followed up for 77.8 ± 7.8 months. GPA detected 20 eyes (48.8%) with progressive RNFL thinning(−1.5 ± 0.5 um/year), who were subsequently classified as the ‘rapid progression group.’ Those whose rate of change in RNFL thickness was slower than −1.00 µm/year was classified as the ‘slow progression group’ (n = 21, −0.0 ± 0.4 um/year, P < 0.001). Mean IOP after initiating therapy was 13.2 ± 1.1 mmHg in the rapid progression group and 13.1 ± 1.3 mmHg in the slow progression group (P = 0.300; 14.8 ± 10.0% vs. 19.6 ± 12.4% reduction, P = 0.155). Disc hemorrhage was found to more frequently occur in the rapid progression group (P = 0.001). Multivariate logistic regression analysis showed that patients with disc hemorrhage were at a higher risk for progressive RNFL thinning in OAG (OR 37.529 95% CI 2.915–483.140) after adjusting for baseline co-variates (P = 0.005). In conclusion, disc hemorrhage is associated with progressive RNFL thinning in OAG with well-maintained IOP. Factors other than IOP appear to also play a role in OAG progression.


2016 ◽  
Vol 23 (4) ◽  
pp. 248-256 ◽  
Author(s):  
Alexander Pleet ◽  
Melanie Sulewski ◽  
Rebecca J. Salowe ◽  
Raymond Fertig ◽  
Julia Salinas ◽  
...  

2021 ◽  
Author(s):  
Alexander K. Schuster ◽  
Felix M. Wagner ◽  
Norbert Pfeiffer ◽  
Esther M. Hoffmann

2018 ◽  
pp. 140-145
Author(s):  
E.A. Egorov ◽  
◽  
V.P. Erichev ◽  
A.L. Onishchenko ◽  
S.Yu. Petrov ◽  
...  

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