scholarly journals Imaging foveal morphology in ocular Albinism using adaptive optics and spectral domain OCT

2009 ◽  
Vol 9 (14) ◽  
pp. 33-33
Author(s):  
J. Carroll ◽  
J. T. McAllister ◽  
S. Ostler ◽  
J. Rha ◽  
A. M. Dubis ◽  
...  
2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Pierre-Maxime Lévêque ◽  
Pierre Zéboulon ◽  
Emmanuelle Brasnu ◽  
Christophe Baudouin ◽  
Antoine Labbé

Purpose. To detect changes in optic nerve head (ONH) vascularization in glaucoma patients using spectral-domain OCT angiography (OCT-A).Material and Method. Fifty glaucoma patients and 30 normal subjects were evaluated with OCT-A (AngioVue®, Optovue). The total ONH vessel density and temporal disc vessel density were measured. Clinical data, visual field (VF) parameters, and spectral-domain OCT evaluation (RNFL: retinal nerve fiber layer thickness, GCC: ganglion cell complex thickness, and rim area) were recorded for glaucoma patients. Correlations among total and temporal ONH vessel density and structural and VF parameters were analyzed.Results. In the glaucoma group, total and temporal ONH vessel density were reduced by 24.7% (0.412 versus 0.547;p<0.0001) and 22.88% (0.364 versus 0.472;p=0.001), respectively, as compared with the control group. Univariate analysis showed significant correlation between rim area (mm2) and temporal ONH vessel density (r=0.623;p<0.0001) and total ONH vessel density (r=0.609;p<0.0001). Significant correlations were found between temporal and total ONH vessel density and RNFL, GCC, VF mean deviation, and visual field index.Conclusion. In glaucoma patients OCT-A might detect reduced ONH blood vessel density that is associated with structural and functional glaucomatous damage. OCT-A might become a useful tool for the evaluation of ONH microcirculation changes in glaucoma.


2013 ◽  
Vol 54 (11) ◽  
pp. 1748
Author(s):  
Geun Yeong Kim ◽  
You Kyung Lee ◽  
Jung Il Moon ◽  
Myoung Hee Park

Ophthalmology ◽  
2018 ◽  
Vol 125 (12) ◽  
pp. 1886-1897 ◽  
Author(s):  
Yu Sawada ◽  
Makoto Araie ◽  
Hitomi Shibata ◽  
Makoto Ishikawa ◽  
Toyoto Iwata ◽  
...  

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Alexi Geevarghese ◽  
Gadi Wollstein ◽  
Hiroshi Ishikawa ◽  
Joel S. Schuman

Early detection and monitoring are critical to the diagnosis and management of glaucoma, a progressive optic neuropathy that causes irreversible blindness. Optical coherence tomography (OCT) has become a commonly utilized imaging modality that aids in the detection and monitoring of structural glaucomatous damage. Since its inception in 1991, OCT has progressed through multiple iterations, from time-domain OCT, to spectral-domain OCT, to swept-source OCT, all of which have progressively improved the resolution and speed of scans. Even newer technological advancements and OCT applications, such as adaptive optics, visible-light OCT, and OCT-angiography, have enriched the use of OCT in the evaluation of glaucoma. This article reviews current commercial and state-of-the-art OCT technologies and analytic techniques in the context of their utility for glaucoma diagnosis and management, as well as promising future directions. Expected final online publication date for the Annual Review of Vision Science, Volume 7 is September 2021. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.


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