scholarly journals Binding in visual working memory is impaired in patients with medial temporal lobe amnesia

2010 ◽  
Vol 6 (6) ◽  
pp. 362-362
Author(s):  
K. S. Moore ◽  
A. Chatterjee ◽  
K. Page ◽  
M. Verfaellie ◽  
I. R. Olson
2012 ◽  
Vol 32 (10) ◽  
pp. 3584-3589 ◽  
Author(s):  
A. Jeneson ◽  
J. T. Wixted ◽  
R. O. Hopkins ◽  
L. R. Squire

2019 ◽  
Vol 134 ◽  
pp. 107227 ◽  
Author(s):  
Robin I. Goodrich ◽  
Trevor L. Baer ◽  
Jörn A. Quent ◽  
Andrew P. Yonelinas

2020 ◽  
Vol 20 (11) ◽  
pp. 797
Author(s):  
Weizhen Xie ◽  
John Wittig Jr ◽  
Sara Inati ◽  
Kareem Zaghloul

2009 ◽  
Vol 47 (1) ◽  
pp. 112-122 ◽  
Author(s):  
Dylan D. Wagner ◽  
Viviane Sziklas ◽  
Krista E. Garver ◽  
Marilyn Jones-Gotman

2009 ◽  
Vol 15 (4) ◽  
pp. 536-546 ◽  
Author(s):  
PABLO CAMPO ◽  
FERNANDO MAESTÚ ◽  
IRENE GARCÍA-MORALES ◽  
ANTONIO GIL-NAGEL ◽  
BRYAN STRANGE ◽  
...  

AbstractIt has been traditionally assumed that medial temporal lobe (MTL) is not required for working memory (WM). However, animal lesion and electrophysiological studies and human neuropsychological and neuroimaging studies have provided increasing evidences of a critical involvement of MTL in WM. Based on previous findings, the central aim of this study was to investigate the contribution of the MTL to verbal WM encoding. Here, we used magnetoencephalography (MEG) to compare the patterns of MTL activation of 9 epilepsy patients suffering from left hippocampal sclerosis with those of 10 healthy matched controls while they performed a verbal WM task. MEG recordings allow detailed tracking of the time course of MTL activation. We observed impaired WM performance associated with changes in the dynamics of MTL activity in epilepsy patients. Specifically, whereas patients showed decreased activity in damaged MTL, activity in the contralateral MTL was enhanced, an effect that became significant in the 600- to 700-ms interval after stimulus presentation. These findings strongly support the crucial contribution of MTL to verbal WM encoding and provide compelling evidence for the proposal that MTL contributes to both episodic memory and WM. Whether this pattern is signaling reorganization or a normal use of a damaged structure is discussed. (JINS, 2009, 15, 536–546.)


2011 ◽  
Vol 71 ◽  
pp. e382
Author(s):  
Masato Inoue ◽  
Masafumi Nejime ◽  
Akichika Mikami

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