scholarly journals Endogenous and exogenous control of visuospatial attention in freely behaving mice.

2019 ◽  
Vol 19 (10) ◽  
pp. 266
Author(s):  
Wen-Kai You ◽  
Shreesh P Mysore
Keyword(s):  
Visuospatial Attention ◽  
Freely Behaving ◽  
Exogenous Control

Deficits In The Exogenous Control Of Covert Visuospatial Attention In Children With Poor Motor Coordination

2010 ◽  
Vol 42 ◽  
pp. 429
Author(s):  
Yu-Ting Tseng ◽  
Chia-Liang Tsai ◽  
Chun-Hao Wang ◽  
Chien-Yu Pan ◽  
Kai-Wen Hsieh
Keyword(s):  
Motor Coordination ◽  
Visuospatial Attention ◽  
Exogenous Control

scholarly journals Endogenous and exogenous control of visuospatial selective attention in freely behaving mice

2019 ◽  
Author(s):  
Wen-Kai You ◽  
Shreesh P. Mysore
Keyword(s):  
Spatial Attention ◽  
Neural Circuit ◽  
Flanker Task ◽  
Visuospatial Attention ◽  
Lower Probability ◽  
Response Accuracy ◽  
Evidence Accumulation ◽  
Spatial Probability ◽  
Probability Task ◽  
Freely Behaving

SUMMARYSelective spatial attention, the ability to dynamically prioritize the most important spatial location, is essential for adaptive behavior. It has been studied primarily in head-fixed animals, and almost exclusively in primates. Here, we report the development of two human-inspired, discrimination-based behavioral paradigms for studying selective visuospatial attention in the freely behaving mouse: the spatial probability task, and the flanker task. In the spatial probability task, we found enhanced response accuracy, perceptual discriminability, and rates of sensory evidence accumulation at the location with higher probability of target occurrence, and opposite effects at the lower probability location. In the absence of systematic differences in sensory input, motor biases, and trial structure, these results demonstrated endogenous expectation-driven shifts of spatial attention. In the flanker task, we found that a second, ‘flanker’ stimulus presented with the target, but with incongruent information, caused switch-like decrements in response accuracy and perceptual discriminability as a function of flanker contrast, as well as a reduced rate of evidence accumulation. These results demonstrated exogenous capture of spatial attention. The innovation of behavioral tasks for selective visuospatial attention in unrestrained mice opens up a rich avenue for future research dissecting the neural circuit mechanisms underlying this critical executive function.

Focusing of Visuospatial Attention

2001 ◽  
Vol 15 (4) ◽  
pp. 256-274 ◽  
Author(s):  
Caterina Pesce ◽  
Rainer Bösel
Keyword(s):  
Reaction Times ◽  
Visual Space ◽  
Spatial Relation ◽  
Stimulus Onset ◽  
Visuospatial Attention ◽  
Task Demands ◽  
Time Interval ◽  
Behavioral Studies ◽  
Task Conditions ◽  
Simple Rt

Abstract In the present study we explored the focusing of visuospatial attention in subjects practicing and not practicing activities with high attentional demands. Similar to the studies of Castiello and Umiltà (e. g., 1990) , our experimental procedure was a variation of Posner's (1980) basic paradigm for exploring covert orienting of visuospatial attention. In a simple RT-task, a peripheral cue of varying size was presented unilaterally or bilaterally from a central fixation point and followed by a target at different stimulus-onset-asynchronies (SOAs). The target could occur validly inside the cue or invalidly outside the cue with varying spatial relation to its boundary. Event-related brain potentials (ERPs) and reaction times (RTs) were recorded to target stimuli under the different task conditions. RT and ERP findings showed converging aspects as well as dissociations. Electrophysiological results revealed an amplitude modulation of the ERPs in the early and late Nd time interval at both anterior and posterior scalp sites, which seems to be related to the effects of peripheral informative cues as well as to the attentional expertise. Results were: (1) shorter latency effects confirm the positive-going amplitude enhancement elicited by unilateral peripheral cues and strengthen the criticism against the neutrality of spatially nonpredictive peripheral cueing of all possible target locations which is often presumed in behavioral studies. (2) Longer latency effects show that subjects with attentional expertise modulate the distribution of the attentional resources in the visual space differently than nonexperienced subjects. Skilled practice may lead to minimizing attentional costs by automatizing the use of a span of attention that is adapted to the most frequent task demands and endogenously increases the allocation of resources to cope with less usual attending conditions.

Early visuospatial attention and processing and related neurodevelopmental outcome at 2 years in children born very preterm

2020 ◽  
Author(s):  
Victoria A. A. Beunders ◽  
Marijn J. Vermeulen ◽  
Jorine A. Roelants ◽  
Nienke Rietema ◽  
Renate M. C. Swarte ◽  
...  
Keyword(s):  
Neurodevelopmental Outcome ◽  
Visuospatial Attention ◽  
Very Preterm

scholarly journals Live imaging of adult neural stem cells in freely behaving mice using mini-endoscopes

2021 ◽  
Vol 2 (2) ◽  
pp. 100596
Author(s):  
Sarah Malvaut ◽  
Alina Marymonchyk ◽  
Archana Gengatharan ◽  
Armen Saghatelyan
Keyword(s):  
Stem Cells ◽  
Neural Stem Cells ◽  
Live Imaging ◽  
Adult Neural Stem Cells ◽  
Freely Behaving

scholarly journals Hippocampus-retrosplenial cortex interaction is increased during phasic REM and contributes to memory consolidation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Daniel Gomes de Almeida-Filho ◽  
Bruna Del Vechio Koike ◽  
Francesca Billwiller ◽  
Kelly Soares Farias ◽  
Igor Rafael Praxedes de Sales ◽  
...  
Keyword(s):  
Rem Sleep ◽  
Memory Consolidation ◽  
Retrosplenial Cortex ◽  
Contextual Fear Conditioning ◽  
Oscillatory Activity ◽  
Theta Oscillation ◽  
Contextual Fear ◽  
Before And After ◽  
Freely Behaving ◽  
Phasic Rem Sleep

AbstractHippocampal (HPC) theta oscillation during post-training rapid eye movement (REM) sleep supports spatial learning. Theta also modulates neuronal and oscillatory activity in the retrosplenial cortex (RSC) during REM sleep. To investigate the relevance of theta-driven interaction between these two regions to memory consolidation, we computed the Granger causality within theta range on electrophysiological data recorded in freely behaving rats during REM sleep, both before and after contextual fear conditioning. We found a training-induced modulation of causality between HPC and RSC that was correlated with memory retrieval 24 h later. Retrieval was proportional to the change in the relative influence RSC exerted upon HPC theta oscillation. Importantly, causality peaked during theta acceleration, in synchrony with phasic REM sleep. Altogether, these results support a role for phasic REM sleep in hippocampo-cortical memory consolidation and suggest that causality modulation between RSC and HPC during REM sleep plays a functional role in that phenomenon.

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