scholarly journals The effect of ultrashort light pulse intensity on human circadian phase

2017 ◽  
Vol 17 (15) ◽  
pp. 43
Author(s):  
Daniel Joyce
Keyword(s):  
Light Pulse ◽  
Ultrashort Light Pulse ◽  
Circadian Phase ◽  
Pulse Intensity

scholarly journals A single dose of alcohol does not meaningfully alter circadian phase advances and phase delays to light in humans

2016 ◽  
Vol 310 (8) ◽  
pp. R759-R765 ◽  
Author(s):  
Helen J. Burgess ◽  
Muneer Rizvydeen ◽  
Louis F. Fogg ◽  
Ali Keshavarzian
Keyword(s):  
Single Dose ◽  
Light Pulse ◽  
Bright Light ◽  
Phase Shifts ◽  
Final Phase ◽  
Circadian Timing ◽  
Circadian Phase ◽  
Sleep Episode ◽  
Late Night ◽  
Laboratory Session

Central circadian timing influences mental and physical health. Research in nocturnal rodents has demonstrated that when alcohol is consumed, it reaches the central hypothalamic circadian pacemaker (suprachiasmatic nuclei) and can directly alter circadian phase shifts to light. In two separate studies, we examined, for the first time, the effects of a single dose of alcohol on circadian phase advances and phase delays to light in humans. Two 23-day within-subjects placebo-controlled counterbalanced design studies were conducted. Both studies consisted of 6 days of fixed baseline sleep to stabilize circadian timing, a 2-day laboratory session, a 6-day break, and a repeat of 6 days of fixed sleep and a 2-day laboratory session. In the phase advance study ( n = 10 light drinkers, 24–45 yr), the laboratory sessions consisted of a baseline dim light phase assessment, sleep episode, alcohol (0.6 g/kg) or placebo, 2-h morning bright light pulse, and final phase assessment. In the phase-delay study ( n = 14 light drinkers, 22–44 yr), the laboratory sessions consisted of a baseline phase assessment, alcohol (0.8 g/kg) or placebo, 2-h late night bright light pulse, sleep episode, and final phase assessment. In both studies, alcohol either increased or decreased the observed phase shifts to light (interaction P ≥ 0.46), but the effect of alcohol vs. placebo on phase shifts to light was always on average smaller than 30 min. Thus, no meaningful effects of a single dose of alcohol vs. placebo on circadian phase shifts to light in humans were observed.

scholarly journals Dual Self-Diffraction Dispersion-scan for Measuring Spatially Inhomogeneous Ultrashort Pulses

2019 ◽  
Vol 205 ◽  
pp. 01025
Author(s):  
Miguel Canhota ◽  
Rosa Weigand ◽  
Helder Crespo
Keyword(s):  
Light Pulse ◽  
Ultrashort Pulses ◽  
Ultrashort Light Pulse ◽  
Spatially Inhomogeneous

We develop a self-diffraction dispersion-scan method that simultaneously measures two distinct spatial portions of an ultrashort light pulse and apply it to the temporal characterization of 400-nm broadband ultraviolet pulses generated by multi-plate continuum.

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