scholarly journals Transcranial direct current stimulation of the right frontal eye field to affect saccade execution

2017 ◽  
Vol 17 (10) ◽  
pp. 898
Author(s):  
Leon Reteig ◽  
Tomas Knapen ◽  
K. Ridderinkhof ◽  
Heleen Slagter
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Frontal Eye Field ◽  
Direct Current Stimulation ◽  
Eye Field ◽  
The Right ◽  
Stimulation Of

High-definition transcranial direct-current stimulation of the right M1 further facilitates left M1 excitability during crossed facilitation

2018 ◽  
Vol 119 (4) ◽  
pp. 1266-1272 ◽  
Author(s):  
Vincent Cabibel ◽  
Makii Muthalib ◽  
Wei-Peng Teo ◽  
Stephane Perrey
Keyword(s):  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Primary Motor Cortex ◽  
Motor Evoked Potentials ◽  
Single Pulse ◽  
High Definition ◽  
Maximum Voluntary Isometric Contraction ◽  
Direct Current Stimulation ◽  
The Right ◽  
Stimulation Of

The crossed-facilitation (CF) effect refers to when motor-evoked potentials (MEPs) evoked in the relaxed muscles of one arm are facilitated by contraction of the opposite arm. The aim of this study was to determine whether high-definition transcranial direct-current stimulation (HD-tDCS) applied to the right primary motor cortex (M1) controlling the left contracting arm [50% maximum voluntary isometric contraction (MVIC)] would further facilitate CF toward the relaxed right arm. Seventeen healthy right-handed subjects participated in an anodal and cathodal or sham HD-tDCS session of the right M1 (2 mA for 20 min) separated by at least 48 h. Single-pulse transcranial magnetic stimulation (TMS) was used to elicit MEPs and cortical silent periods (CSPs) from the left M1 at baseline and 10 min into and after right M1 HD-tDCS. At baseline, compared with resting, CF (i.e., right arm resting, left arm 50% MVIC) increased left M1 MEP amplitudes (+97%) and decreased CSPs (−11%). The main novel finding was that right M1 HD-tDCS further increased left M1 excitability (+28.3%) and inhibition (+21%) from baseline levels during CF of the left M1, with no difference between anodal and cathodal HD-tDCS sessions. No modulation of CSP or MEP was observed during sham HD-tDCS sessions. Our findings suggest that CF of the left M1 combined with right M1 anodal or cathodal HD-tDCS further facilitated interhemispheric interactions during CF from the right M1 (contracting left arm) toward the left M1 (relaxed right arm), with effects on both excitatory and inhibitory processing. NEW & NOTEWORTHY This study shows modulation of the nonstimulated left M1 by right M1 HD-tDCS combined with crossed facilitation, which was probably achieved through modulation of interhemispheric interactions.

scholarly journals Efficiency of Repetitive Transcranial Direct Current Stimulation of the Dorsolateral Prefrontal Cortex in Disorders of Consciousness: A Randomized Sham-Controlled Study

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Min Wu ◽  
Yamei Yu ◽  
Lunjie Luo ◽  
Yuehao Wu ◽  
Jian Gao ◽  
...  
Keyword(s):  
Prefrontal Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Dorsolateral Prefrontal Cortex ◽  
Disorders Of Consciousness ◽  
Anodal Tdcs ◽  
Direct Current Stimulation ◽  
Dorsolateral Prefrontal ◽  
The Right ◽  
Stimulation Of

Conventional transcranial direct current stimulation (tDCS) targeting the left dorsolateral prefrontal cortex (DLPFC) could improve arousal in disorders of consciousness (DOC). However, the comparative effectiveness of anodal stimulation of the left DLPFC and the electrophysiological effect of tDCS are yet to be determined. In this randomized sham-controlled design, patients were separated into three groups (left/right anodal tDCS, sham). Data on the clinical assessments and EEG were collected at baseline and after 2 weeks of tDCS. The outcome at 3-month follow-up was evaluated using the Glasgow Outcome Scale-Extended. Results showed that sessions of the left tDCS facilitated the excitability of the prefrontal cortex, whereas only one patient had a positive outcome. Targeting the right DLPFC was less effective, merely leading to activation of the stimulation site, with no effect on the state of arousal. Moreover, sham stimulation had minimal or no effect on any of the outcomes. These results provide evidence for a hemispheric asymmetry of tDCS effects in patients with DOC. Left anodal tDCS might be more effective for modulating cortical excitability compared to tDCS on the right DLPFC. However, future studies with large sample sizes are needed to confirm these findings. This trial is registered with NCT03809936.

scholarly journals Prefrontal Transcranial Direct Current Stimulation Globally Improves Learning but Does Not Selectively Potentiate the Benefits of Targeted Memory Reactivation on Awake Memory Consolidation

2021 ◽  
Vol 11 (8) ◽  
pp. 1104
Author(s):  
Médhi Gilson ◽  
Michael A. Nitsche ◽  
Philippe Peigneux
Keyword(s):  
Direct Current ◽  
Memory Consolidation ◽  
Transcranial Direct Current Stimulation ◽  
Specific Effect ◽  
Memory Reactivation ◽  
Direct Current Stimulation ◽  
Beneficial Effects ◽  
Anodal Stimulation ◽  
The Right ◽  
Stimulation Of

Targeted memory reactivation (TMR) and transcranial direct current stimulation (tDCS) can enhance memory consolidation. It is currently unknown whether TMR reinforced by simultaneous tDCS has superior efficacy. In this study, we investigated the complementary effect of TMR and bilateral tDCS on the consolidation of emotionally neutral and negative declarative memories. Participants learned neutral and negative word pairs. Each word pair was presented with an emotionally compatible sound. Following learning, participants spent a 20 min retention interval awake under four possible conditions: (1) TMR alone (i.e., replay of 50% of the associated sounds), (2) TMR combined with anodal stimulation of the left DLPFC, (3) TMR combined with anodal stimulation of the right DLPFC and (4) TMR with sham tDCS. Results evidenced selective memory enhancement for the replayed stimuli in the TMR-only and TMR-sham conditions, which confirms a specific effect of TMR on memory. However, memory was enhanced at higher levels for all learned items (irrespective of TMR) in the TMR-anodal right and TMR-anodal left tDCS conditions, suggesting that the beneficial effects of tDCS overshadow the specific effects of TMR. Emotionally negative memories were not modulated by tDCS hemispheric polarity. We conclude that electrical stimulation of the DLPFC during the post-learning period globally benefits memory consolidation but does not potentiate the specific benefits of TMR.

scholarly journals Transcranial direct current stimulation of the posterior parietal cortex biases human hand choice

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kento Hirayama ◽  
Takayuki Koga ◽  
Toru Takahashi ◽  
Rieko Osu
Keyword(s):  
Reaction Time ◽  
Parietal Cortex ◽  
Direct Current ◽  
Transcranial Direct Current Stimulation ◽  
Posterior Parietal Cortex ◽  
Human Hand ◽  
Direct Current Stimulation ◽  
Posterior Parietal ◽  
The Right ◽  
Stimulation Of

AbstractHand choices—deciding which hand to use to reach for targets—represent continuous, daily, unconscious decisions. The posterior parietal cortex (PPC) contralateral to the selected hand is activated during a hand-choice task, and disruption of left PPC activity with a single-pulse transcranial magnetic stimulation prior to the execution of the motion suppresses the choice to use the right hand but not vice versa. These findings imply the involvement of either bilateral or left PPC in hand choice. To determine whether the effects of PPC’s activity are essential and/or symmetrical in hand choice, we increased or decreased PPC excitability in 16 healthy participants using transcranial direct current stimulation (tDCS; 10 min, 2 mA, 5 × 7 cm) and examined its online and residual effects on hand-choice probability and reaction time. After the right PPC was stimulated with an anode and the left PPC with a cathode, the probability of left-hand choice significantly increased and reaction time significantly decreased. However, no significant changes were observed with the stimulation of the right PPC with a cathode and the left PPC with an anode. These findings, thus, reveal the asymmetry of PPC-mediated regulation in hand choice.

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