scholarly journals Using SSVEPs to measure brain responses of chronic cannabis users and nonusers to during a visual recognition task

2016 ◽  
Vol 16 (12) ◽  
pp. 530
Author(s):  
Brandi Emerick ◽  
Tom Busey ◽  
Brian O'Donnell
1975 ◽  
Vol 66 (3) ◽  
pp. 289-298 ◽  
Author(s):  
ANTHONY GALE ◽  
GRAHAM SPRATT ◽  
BRUCE CHRISTIE ◽  
ADRIAN SMALLBONE

2006 ◽  
Vol 72 (719) ◽  
pp. 2248-2256 ◽  
Author(s):  
Kimihiro YAMANAKA ◽  
Hidetoshi NAKAYASU ◽  
Tetsuya MIYOSHI ◽  
Kazuaki MAEDA

1967 ◽  
Vol 74 (4, Pt.1) ◽  
pp. 543-549 ◽  
Author(s):  
Howard Egeth ◽  
Edward E. Smith

1975 ◽  
Vol 40 (1) ◽  
pp. 143-151
Author(s):  
June M. Tuma

The present investigation tested the hypothesis advanced by J. Inglis (1961) that perceptual defense and perceptual vigilance result from an interaction between personality differences and degrees of experimental stress. The design, which controlled for questionable procedures used in previous studies, utilized 32 introverts and 32 extraverts, half male and half female, in an experiment with a visual recognition-task. Results indicated that under low-stress conditions introverts and extraverts identified by their response to a thematic apperception task react to threatening stimuli with perceptual defense and perceptual vigilance, respectively. Under high-stress conditions, type of avoidance activity reverses; extraverts react with perceptual defense and introverts with perceptual vigilance. It was suggested that, when both personality and stress variables are controlled, results of the perceptual defense paradigm are predictable and consistent, in support of Inglis' hypothesis.


1979 ◽  
Vol 9 (3) ◽  
pp. 263-272 ◽  
Author(s):  
N. H. Kirby ◽  
T. Nettelbeck ◽  
S. Goodenough

Three groups, one of elderly, one of young mentally retarded, and one of non-retarded young persons were compared on a visual recognition task which involved changing from one category of identification to another. The mentally retarded participants had greater difficulty in changing categories than did the non-retarded participants. Results for the elderly were similar but may have been partly due to the choice of stimulus material. In a second task, the same elderly and non-retarded young participants named as many objects as possible in one minute. The elderly group produced fewer responses on average than the young group and fewer categories of such responses. Results suggested that older persons find it more difficult to change between different categories of identification.


2019 ◽  
Vol 78 (7) ◽  
pp. 934-940 ◽  
Author(s):  
Michelle Barraclough ◽  
Shane McKie ◽  
Ben Parker ◽  
Alan Jackson ◽  
Philip Pemberton ◽  
...  

ObjectivesCognitive dysfunction (CD) is common in systemic lupus erythematosus (SLE) but the cause remains unclear and treatment options are limited. We aimed to compare cognitive function in SLE and healthy controls (HCs) using both behavioural and neuroimaging techniques.MethodsPatients with SLE with stable disease and HCs were recruited. Clinical and psychological data were collected along with a blood sample for relevant biomarkers. Neurocognitive function was assessed using tests from the Cambridge Neuropsychological Test Automated Battery (CANTAB) and functional magnetic resonance imaging (fMRI) was used to examine brain responses to working memory (WM) and emotional processing (facial emotional recognition task, FERT) tasks.ResultsCompared with HCs (n=30), patients with SLE (n=36) scored higher on measures of depression, fatigue and had higher hsCRP (p=0.013), IL-6 (p=0.003) and B lymphocyte stimulator (p<0.001). Patients with SLE had poorer performance on a task of sustained attention (p=0.002) and had altered brain responses, particularly in default mode network (DMN) regions and the caudate, during the WM task. Higher organ damage and higher VCAM-1 were associated with less attenuation of the DMN (p=0.005 and p=0.01, respectively) and lower BOLD signal in the caudate areas (p=0.005 and p=0.001, respectively). Increased IL-6 was also associated with lower BOLD signal in caudate areas (p=0.032).ConclusionsSustained attention was impaired in patients with SLE. Poor attenuation of the DMN may contribute to cognitive impairments in SLE and our data suggest that in addition to mood and fatigue inflammatory mechanisms and organ damage impact cognitive functioning in SLE. The multifaceted nature of CD in SLE means any therapeutic interventions should be individually tailored.


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