scholarly journals Pain Tolerance Predicts Spatial But Not Temporal Vision Thresholds in Human Adults

2014 ◽  
Vol 14 (10) ◽  
pp. 1419-1419
Author(s):  
M. E. Mercer ◽  
G. L. Smith ◽  
P. A. S. Sheppard
Keyword(s):  
Pain Tolerance ◽  
Temporal Vision ◽  
Human Adults

L-arginine effect on inflammatory mediators: A systematic review of randomized controlled clinical trials

2019 ◽  
pp. 1-9 ◽  
Author(s):  
Seyed Reza Mirhafez ◽  
Mitra Hariri
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Inflammatory Mediators ◽  
Randomized Clinical Trials ◽  
Randomized Controlled Clinical Trials ◽  
Patients With Cancer ◽  
Reactive Protein ◽  
Randomized Controlled ◽  
Human Adults ◽  
Factor Α

Abstract. L-arginine is an important factor in several physiological and biochemical processes. Recently, scientists studied L-arginine effect on inflammatory mediators such as C-reactive protein (CRP), tumor necrosis factor-α (TNF-α) and interleukin-6 (IL-6). We conducted a systematic review on randomized controlled trials assessing L-arginine effect on inflammatory mediators. We searched data bases including Google scholar, ISI web of science, SCOPUS, and PubMed/Medline up to April 2019. Randomized clinical trials assessing the effect of L-arginine on inflammatory mediators in human adults were included. Our search retrieved eleven articles with 387 participants. Five articles were on patients with cancer and 6 articles were on adults without cancer. L-arginine was applied in enteral form in 5 articles and in oral form in 6 articles. Eight articles were on both genders, two articles were on women, and one article was on men. L-arginine could not reduce inflammatory mediators among patients with and without cancer except one article which indicated that taking L-arginine for 6 months decreased IL-6 among cardiopathic nondiabetic patients. Our results indicated that L-arginine might not be able to reduce selected inflammatory mediators, but for making a firm decision more studies are needed to be conducted with longer intervention duration, separately on male and female and with different doses of L-arginine.

Interactive Effects of Acute Suicidal Affective Disturbance and Pain Persistence on Suicide Attempt Frequency and Lethality

Crisis ◽  
2019 ◽  
Vol 40 (6) ◽  
pp. 413-421 ◽  
Author(s):  
Megan L. Rogers ◽  
Thomas E. Joiner
Keyword(s):  
Suicide Attempt ◽  
Suicidal Behavior ◽  
Pain Perception ◽  
Suicide Attempts ◽  
Pain Tolerance ◽  
Self Report ◽  
Interactive Effects ◽  
Physical Pain ◽  
Affective Disturbance ◽  
The Relationship

Abstract. Background: Acute suicidal affective disturbance (ASAD) has been proposed as a suicide-specific entity that confers risk for imminent suicidal behavior. Preliminary evidence suggests that ASAD is associated with suicidal behavior beyond a number of factors; however, no study to date has examined potential moderating variables.  Aims: The present study tested the hypotheses that physical pain persistence would moderate the relationship between ASAD and (1) lifetime suicide attempts and (2) attempt lethality. Method: Students ( N = 167) with a history of suicidality completed self-report measures assessing the lifetime worst-point ASAD episode and the presence of a lifetime suicide attempt, a clinical interview about attempt lethality, and a physical pain tolerance task. Results: Physical pain persistence was a significant moderator of the association between ASAD and lifetime suicide attempts ( B = 0.00001, SE = 0.000004, p = .032), such that the relationship between ASAD and suicide attempts strengthened at increasing levels of pain persistence. The interaction between ASAD and pain persistence in relation to attempt lethality was nonsignificant ( B = 0.000004, SE = 0.00001, p = .765). Limitations: This study included a cross-sectional/retrospective analysis of worst-point ASAD symptoms, current physical pain perception, and lifetime suicide attempts. Conclusion: ASAD may confer risk for suicidal behavior most strongly at higher levels of pain persistence, whereas ASAD and pain perception do not influence attempt lethality.

Pain tolerance, personality, and autonomic measures

1970 ◽  
Author(s):  
Daisy Schalling ◽  
Anita Rissler ◽  
Gunnar Edman
Keyword(s):  
Pain Tolerance

Facial structure predicts decreased inhibition: From pain tolerance to baseball swings

2014 ◽  
Author(s):  
Jordan Blake Leitner ◽  
Eric Hehman ◽  
James M. Jones ◽  
Adam B. Magerman ◽  
Matthew P. Deegan
Keyword(s):  
Pain Tolerance ◽  
Facial Structure

The Origins of Intentional Agency

2020 ◽  
Author(s):  
Lorijn Zaadnoordijk ◽  
Tim Bayne
Keyword(s):  
Developmental Theory ◽  
Sense Of Agency ◽  
Intentional Agency ◽  
Human Adults ◽  
Intentional Agents

As human adults, we experience ourselves as intentional agents. Here, we address how intentional agency and the corresponding agentive experiences emerge in infancy. When formulating a developmental theory of intentional agency, we encounter a so-called paradox of agency: three plausible theses regarding intentional agency that in combination seem to make it impossible for the developing infant to acquire a sense of agency. By recognizing various types of intentions, we propose a framework in which the paradox can be resolved, allowing infants to bootstrap their way to becoming intentional agents and experiencing a sense of agency.

Investigation of ACE rs4646994, MTHFR rs1801133 and VDR rs2228570 Genotypes in Jordanian Patients with Fibromyalgia Syndrome

2020 ◽  
Vol 21 ◽  
Author(s):  
Raida Khalil ◽  
Wajdy J. Al-Awaida ◽  
Hamzeh J. Al-Ameer ◽  
Yazun Jarrar ◽  
Amer Imraish ◽  
...  
Keyword(s):  
Sleep Disturbances ◽  
Fibromyalgia Syndrome ◽  
Methylenetetrahydrofolate Reductase ◽  
Pain Tolerance ◽  
The Body ◽  
Restless Leg Syndrome ◽  
Jordanian Arabic ◽  
Clinical Investigations ◽  
Polymerase Chain ◽  
Larger Sample

Background: Fibromyalgia syndrome (FMS) is a chronic disease characterized by widespread body pain, weakness in certain parts of the body (critical points), low pain tolerance, sleep disturbances, and fatigue. This syndrome is considered rare in Jordan. Objectives: The research aimed to find out the association of the angiotensin converting enzyme, methylenetetrahydrofolate reductase, and vitamin D receptor (ACE, MHFTR, and VDR, respectively) genotypes with FMS among Jordanian patients. Methods: This work included 22 FM patients and 22 healthy individuals of Jordanian Arabic origin. The ACE rs4646994, MTHFR rs1801133, and VDR rs2228570 genotypes were determined using polymerase chain reaction (PCR) followed by restriction fragment length polymorphism. Results: No associations between ACE rs4646994, MTHFR rs1801133, and VDR rs2228570 with the vulnerability of a person for the development of FMS were found. However, we found an association between the ACE rs4646994 genotype and restless leg among FM patients. Conclusion: Based on result from this study, it appears that the ACE rs4646994 genotype is associated with restless leg among FMS patients of Jordanian origin. Further clinical investigations with larger sample sizes are required to confirm these findings and to understand the molecular mechanism of ACE rs4646994 genetic variant in the restless leg syndrome among FM patients.

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