scholarly journals Large-scale functional distinctions in object cortex are reflected in resting state networks

2013 ◽  
Vol 13 (9) ◽  
pp. 494-494
Author(s):  
T. Konkle ◽  
A. Caramazza
2019 ◽  
Vol 76 (6) ◽  
pp. 624 ◽  
Author(s):  
Narun Pornpattananangkul ◽  
Ellen Leibenluft ◽  
Daniel S. Pine ◽  
Argyris Stringaris

2018 ◽  
Author(s):  
Dόra Szabό ◽  
Kálmán Czeibert ◽  
Ádám Kettinger ◽  
Márta Gácsi ◽  
Attila Andics ◽  
...  

ABSTRACTResting-state networks are spatially distributed, functionally connected brain regions. Studying these networks gives us information about the large-scale functional organization of the brain and alternations in these networks are considered to play a role in a wide range of neurological conditions and aging. To describe resting-state networks in dogs, we measured 22 awake, unrestrained animals of either sex and carried out group-level spatial independent component analysis to explore whole-brain connectivity patterns. Using resting-state functional magnetic resonance imaging (rs-fMRI), in this exploratory study we found multiple resting-state networks in dogs, which resemble the pattern described in humans. We report the following dog resting-state networks: default mode network (DMN), visual network (VIS), sensorimotor network (SMN), combined auditory (AUD)-saliency (SAL) network and cerebellar network (CER). The DMN, similarly to Primates, but unlike previous studies in dogs, showed antero-posterior connectedness with involvement of hippocampal and lateral temporal regions. The results give us insight into the resting-state networks of awake animals from a taxon beyond rodents through a non-invasive method.


2016 ◽  
Author(s):  
Michael W. Cole ◽  
Takuya Ito ◽  
Danielle S. Bassett ◽  
Douglas H. Schultz

AbstractResting-state functional connectivity (FC) has helped reveal the intrinsic network organization of the human brain, yet its relevance to cognitive task activations has been unclear. Uncertainty remains despite evidence that resting-state FC patterns are highly similar to cognitive task activation patterns. Identifying the distributed processes that shape localized cognitive task activations may help reveal why resting-stateFC is so strongly related to cognitive task activations. We found that estimating task-evoked activity flow (the spread of activation amplitudes) over resting-state FC networks allows prediction of cognitive task activations in a large-scale neural network model. Applying this insight to empirical functional MRI data, we found that cognitive task activations can be predicted in held-out brain regions (and held-out individuals via estimated activity flow over resting-state FC networks. This suggests that task-evoked activity flow over intrinsic networks is a large-scale mechanism explaining the relevance of resting-state FC to cognitive task activations.


2020 ◽  
Vol 80 ◽  
pp. 56-61
Author(s):  
Inbal Maidan ◽  
Amgad Droby ◽  
Yael Jacob ◽  
Nir Giladi ◽  
Jeffrey M Hausdorff ◽  
...  

2015 ◽  
Vol 36 (3) ◽  
pp. 463-473 ◽  
Author(s):  
Weiying Dai ◽  
Gopal Varma ◽  
Rachel Scheidegger ◽  
David C Alsop

Blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) has been widely used to investigate spontaneous low-frequency signal fluctuations across brain resting state networks. However, BOLD only provides relative measures of signal fluctuations. Arterial Spin Labeling (ASL) MRI holds great potential for quantitative measurements of resting state network fluctuations. This study systematically quantified signal fluctuations of the large-scale resting state networks using ASL data from 20 healthy volunteers by separating them from global signal fluctuations and fluctuations caused by residual noise. Global ASL signal fluctuation was 7.59% ± 1.47% relative to the ASL baseline perfusion. Fluctuations of seven detected resting state networks vary from 2.96% ± 0.93% to 6.71% ± 2.35%. Fluctuations of networks and residual noise were 6.05% ± 1.18% and 6.78% ± 1.16% using 4-mm resolution ASL data applied with Gaussian smoothing kernel of 6mm. However, network fluctuations were reduced by 7.77% ± 1.56% while residual noise fluctuation was markedly reduced by 39.75% ± 2.90% when smoothing kernel of 12 mm was applied to the ASL data. Therefore, global and network fluctuations are the dominant structured noise sources in ASL data. Quantitative measurements of resting state networks may enable improved noise reduction and provide insights into the function of healthy and diseased brain.


2021 ◽  
Author(s):  
Jessica A. Bernard ◽  
Hannah K. Ballard ◽  
T. Bryan Jackson

AbstractCerebellar contributions to behavior in advanced age are of great interest and importance, given its role in motor and cognitive performance. There are differences and declines in cerebellar structure in advanced age, and cerebellar resting state connectivity is decreased. However, the work on this area to date has focused on the cerebellar cortex. The deep cerebellar nuclei provide the primary cerebellar inputs and outputs to the cortex, as well as the spinal and vestibular systems. In both human and non-human primate models, dentate networks can be dissociated such that dorsal region is associated with the motor cortex, while the ventral aspect is associated with the prefrontal cortex. However, whether or not dentato-thalamo-cortical networks differ across adulthood remains unknown. Here, using a large adult sample (n=591) from the Cambridge Center for Ageing and Neuroscience, we investigated dentate connectivity across adulthood. First, we replicated past work showing dissociable resting state networks in the dorsal and ventral aspects of the dentate. Second, in both seeds, we demonstrated connectivity decreases with age, indicating that connectivity differences extend beyond the cerebellar cortex. This expands our understanding of cerebellar circuitry in advanced age, and further underscores the potential importance of this structure in age-related performance differences.


2016 ◽  
Vol 6 (2) ◽  
pp. 122-135 ◽  
Author(s):  
Han Yuan ◽  
Lei Ding ◽  
Min Zhu ◽  
Vadim Zotev ◽  
Raquel Phillips ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document