scholarly journals Boundary contour of binocular rivalry stimulus affects activities in ocular dominance columns (V1) of anesthetized macaque monkeys

2012 ◽  
Vol 12 (9) ◽  
pp. 42-42
Author(s):  
C. Han ◽  
H. Xu ◽  
M. Chen ◽  
P. Li ◽  
S. Zhu ◽  
...  
Keyword(s):  
Binocular Rivalry ◽  
Ocular Dominance ◽  
Boundary Contour ◽  
Macaque Monkeys ◽  
Ocular Dominance Columns

scholarly journals Discrete reduction patterns of parvalbumin and calbindin D-28k immunoreactivity in the dorsal lateral geniculate nucleus and the striate cortex of adult macaque monkeys after monocular enucleation

1994 ◽  
Vol 11 (1) ◽  
pp. 1-11 ◽  
Author(s):  
Ingmar Blümcke ◽  
Eduardo Weruaga ◽  
Sandor Kasas ◽  
Anita E. Hendrickson ◽  
Marco R. Celio
Keyword(s):  
Calcium Binding ◽  
Ocular Dominance ◽  
Dorsal Lateral Geniculate Nucleus ◽  
Projection Neurons ◽  
Macaque Monkeys ◽  
Ocular Dominance Columns ◽  
Monocular Enucleation ◽  
Metabolic Marker ◽  
Cortical Interneurons ◽  
Calbindin D

AbstractWe analyzed the immunohistochemical distribution of the two calcium-binding proteins, parvalbumin (PV) and calbindin D-28k (CB), in the primary visual cortex and lateral dorsal geniculate nucleus (dLGN) of monocularly enucleated macaque monkeys (Macaca fascicularis and Macaca nemestrind) in order to determine how the expression of PV and CB is affected by functional inactivity. The monkeys survived 1–17 weeks after monocular enucleation. The distribution pattern of each of the proteins was examined immunocytochemically using monoclonal antibodies and compared with that of the metabolic marker cytochrome oxidase (CO). We recorded manually the number of immunostained neurons and estimated the concentration of immunoreactive staining product using a computerized image-acquisition system. Our results indicate a decrease of approximately 30% in the labeling of PV-immunoreactive (ir) neuropil particularly in those layers of denervated ocular-dominance columns receiving the geniculocortical input. There was no change in the number of PV-ir neurons in any compartment irrespective of the enucleation interval. For CB-ir, we found a 20% decrease in the neuropil labeling in layer 2/3 of the denervated ocular-dominance columns. In addition, a subset of pyramidal CB-ir neurons in layers 2 and 4B, which are weakly stained in control animals, showed decreased labeling. In the dLGN of enucleated animals, PV-ir and CB-ir were decreased only in the neuropil of the denervated layers.From these results, we conclude that cortical interneurons and geniculate projection neurons still express PV and CB in their cell bodies after disruption of the direct functional input from one eye. The only distinct decrease of PV and CB expression is seen in axon terminals from retinal ganglion cells in the dLGN, and in the axons and terminals of both geniculocortical projection cells and cortical interneurons in the cerebral cortex.

Organization of ocular dominance and orientation columns in the striate cortex of neonatal macaque monkeys

1995 ◽  
Vol 12 (3) ◽  
pp. 589-603 ◽  
Author(s):  
Gary Blasdel ◽  
Klaus Obermayer ◽  
Lynne Kiorpes
Keyword(s):  
Striate Cortex ◽  
Ocular Dominance ◽  
Striking Difference ◽  
Cortical Surface ◽  
Comparable Amount ◽  
Macaque Monkeys ◽  
Ocular Dominance Columns ◽  
Orientation Columns ◽  
Orientation Specificity ◽  
Organizational Features

AbstractPrevious work has shown that small, stimulus-dependent changes in light absorption can be used to monitor cortical activity, and to provide detailed maps of ocular dominance and optimal stimulus orientation in the striate cortex of adult macaque monkeys (Blasdel & Salama, 1986; Ts'o et al., 1990). We now extend this approach to infant animals, in which we find many of the organizational features described previously in adults, including patch-like linear zones, singularities, and fractures (Blasdel, 1992b), in animals as young as 3/12 weeks of age. Indeed, the similarities between infant and adult patterns are more compelling than expected. Patterns of ocular dominance and orientation, for example, show many of the correlations described previously in adults, including a tendency for orientation specificity to decrease in the centers of ocular dominance columns, and for iso-orientation contours to cross the borders of ocular dominance columns at angles of 90 deg. In spite of these similarities, there are differences, one of which entails the strength of ocular dominance signals, which appear weaker in the younger animals and which increase steadily with age. Another, more striking, difference concerns the widths of ocular dominance columns, which increase by 20% during the first 3 months of life. Since the cortical surface area increases by a comparable amount, during the same time, this 20% expansion implies that growth occurs anisotropically, perpendicular to the ocular dominance columns, as the cortical surface expands. Since the observed patterns of orientation preference expand more slowly, at approximately half this rate, these results also imply that ocular dominance and orientation patterns change their relationship, and may even drift past one another, as young animals mature.

Ocular dominance columns in area 17 of Old World macaque and talapoin monkeys: Complete reconstructions and quantitative analyses

1992 ◽  
Vol 8 (5) ◽  
pp. 449-462 ◽  
Author(s):  
S. L. Florence ◽  
J. H. Kaas
Keyword(s):  
Optic Disc ◽  
Striate Cortex ◽  
Ocular Dominance ◽  
Macaque Monkey ◽  
Monocular Deprivation ◽  
Old World ◽  
Macaque Monkeys ◽  
Ocular Dominance Columns ◽  
Quantitative Analyses ◽  
Contralateral Eye

AbstractThe effects of monocular deprivation on cytochrome-oxidase (CO) expression were used to reveal ocular dominance columns in flatmounts of the striate cortex in macaque (Macaca fascicularis) and talapoin (Miopithecus talapoin) monkeys. This procedure allowed the first direct visualization of the complete pattern of ocular dominance bands in macaque monkeys, and less complete reconstructions in talapoin monkeys. In a second macaque monkey, the ocular dominance organization was revealed by injecting wheat germ agglutinin conjugated to horseradish peroxidase (WGA-HRP) into one eye.The organization of ocular dominance columns in the macaque monkeys conforms to previous descriptions, but the flat-mounted hemispheres provide accurate details on (1) the arrangement of columns, (2) the orientation of the representation of the optic disc, and (3) the breakdown of the bands in the cortex between the optic disc and monocular representations into a pattern of dots activated by the ipsilateral eye and larger surrounds related to the contralateral eye.Talapoin monkeys, the smallest of Old World monkeys, have sharply segregated ocular dominance bands. The columns in talapoins are narrower than those in macaques, so that even with less striate cortex than macaques, talapoins have more ocular dominance hypercolumns.

scholarly journals Correlation model for joint development of refined retinotopic map and ocular dominance columns

2002 ◽  
Vol 42 (19) ◽  
pp. 2295-2310 ◽  
Author(s):  
Greg A. Woodbury ◽  
Rick van der Zwan ◽  
William G. Gibson
Keyword(s):  
Ocular Dominance ◽  
Correlation Model ◽  
Ocular Dominance Columns ◽  
Joint Development ◽  
Retinotopic Map
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