An Experimental Analysis of Composite Nursing Material of Degradable Magnesium/Polylactic Acid in the Treatment of Postoperative Pain After Orthopedic Surgery

2020 ◽  
Vol 12 (6) ◽  
pp. 842-852
Author(s):  
Yongli Feng ◽  
Li Yu ◽  
Yanjie Liu ◽  
Xiaoyuan Wu ◽  
Ying Wang ◽  
...  
Keyword(s):  
Composite Material ◽  
Postoperative Pain ◽  
Internal Fixation ◽  
Lower Limb ◽  
Open Reduction ◽  
Magnesium Fluoride ◽  
Magnesium Powder ◽  
Group 4 ◽  
Lower Limb Fractures ◽  
Limb Fractures

In this study, magnesium is used as the modified material of polylactic acid (PLA). In the process of combining magnesium and PLA, the magnesium powder is pre-treated with fluorine conversion, that is, the surface of the magnesium powder would form a fluoride membrane, and then it is compounded with PLA to form Mg-F-PA. In the experiment, the morphology of the material is analyzed first. Magnesium powder and magnesium fluoride powder are evenly dispersed on the surface of the composite material, and the surface of the composite material is relatively flat. At the same time, it is found in the mechanical analysis that the mechanical strength of composite Mg-F-PA decreases compared with that of single PLA, but the binding force of magnesium fluoride powder + PLA is stronger than that of magnesium powder + PLA. 120 patients with lower extremity fractures of ASA I∼III are selected and divided into 4 groups, with 30 cases in each group. These patients are treated with hip replacement (group 1), artificial femoral head replacement (group 2), open reduction and internal fixation for lower limb fractures (group 3), open reduction and internal fixation for lower limb fractures + Mg-F-PA (group 4). Then, postoperative evaluation is conducted. The clinical results show that the group 4 is better than the other 3 groups in terms of the sedation degree score, the number of pain pump presses and the incidence of postoperative adverse reactions (P < 0.05). Therefore, the orthopedic material that proposed in this study can reduce postoperative pain.

scholarly journals Clinical and Radiological Outcomes After Surgical Treatment of Lower Limb Fractures in Patients With Spinal Cord Injury

2019 ◽  
Vol 10 (6) ◽  
pp. 715-719
Author(s):  
Lars Ung ◽  
Malte Ohlmeier ◽  
Birger Jettkant ◽  
Dennis Grasmücke ◽  
Mirko Aach ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Internal Fixation ◽  
Lower Limb ◽  
Bone Consolidation ◽  
Lower Limb Fractures ◽  
Kaplan Meier ◽  
Cord Injury ◽  
Limb Fractures ◽  
Consolidation Time ◽  
Internal Group

Study Design: Retrospective observational study. Objectives: To analyze the clinical and radiological outcomes of lower limb fractures following surgical treatment in patients with chronic spinal cord injury (SCI). Methods: Between January 2003 and December 2015, 102 chronic SCI patients with a lower limb fracture were surgically treated at our hospital. A total of 58 patients met the inclusion criteria and were recruited for final analysis. Patients with 2-stage procedure or incomplete clinical records with lost-to-follow-up were excluded from the study. Patients were divided into 2 groups (group 1= internal fixation; group 2 = external fixation). Primary outcome measures were to identify the number of nonunions via Kaplan-Meier analysis and the time to bone consolidation. The diagnosis of a pseudarthrosis was made after more than 180 days of consolidation time. Considering the Kaplan-Meier analysis, pseudarthrosis was interpreted as treatment failure. Secondary outcome measure was to evaluate the complication rate with special focus on heterotopic ossification. Results: A total of 58 chronic SCI patients with closed bone fractures were included in this study. Fifty-two fractures (88%) were simple and 7 (12%) were complex (type C) fractures according to AO classification. The majority of patients (34 cases, 59%) developed femur fractures followed by 24 tibial fractures (41%). Seventeen patients received an external (29%) and 41 an internal fixation (71%). Bone consolidation was reported in 31 patients (53%) with a mean time interval of bone consolidation after 97 days (range from 45 to 160 days; SD = 30). The reported nonunion (pseudarthrosis) rate was 47%. Comparing the internal group (n = 15 patients) versus the external group (n = 14), we could not find any significant difference ( P = .939) concerning the bone consolidation time. The Kaplan-Meier analysis showed a 75% cumulative survivorship at 120 days (internal group) versus 111 days (external group). Most common postoperative complications occurred in the internal fixation group with Wound infections being predominantly observed (10%), followed by heterotopic ossifications (8%). Conclusions: Our results show that surgical treatment of lower limb fractures in chronic SCI patients is a challenging treatment with a high pseudarthrosis rate in both groups. The complication rate seems to be lower in the patients treated with external fixation. As a clinical recommendation, longer implants should be used for a stable osteosynthesis since SCI patients seem to have a higher load on the osteosynthesis material due to missing sensomotoric feedback.

Studying variables affecting the length of stay in patients with lower limb fractures by means of Machine Learning

2021 ◽  
Author(s):  
Ylenia Colella ◽  
Arianna Scala ◽  
Chiara De Lauri ◽  
Francesco Bruno ◽  
Giuseppe Cesarelli ◽  
...  
Keyword(s):  
Machine Learning ◽  
Length Of Stay ◽  
Lower Limb ◽  
Lower Limb Fractures ◽  
Limb Fractures

Technical aspects and complications in the surgical treatment of poliomyelitis-affected lower limb fractures

2018 ◽  
Vol 62 (4) ◽  
pp. 257-266
Author(s):  
J. Mingo-Robinet ◽  
J.A. Alonso ◽  
M. Moreno-Barrero ◽  
L. González-García ◽  
V. Garcia-Virto ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Lower Limb ◽  
Technical Aspects ◽  
Lower Limb Fractures ◽  
Limb Fractures

External Fixation Of Lower Limb Fractures In Children

2000 ◽  
Vol 35 (6) ◽  
pp. 851
Author(s):  
Tae Woo Park ◽  
Sung Do Cho ◽  
Yong Sun Cho ◽  
Bum Soo Kim ◽  
Soon Woo Hong ◽  
...  
Keyword(s):  
External Fixation ◽  
Lower Limb ◽  
Lower Limb Fractures ◽  
Fractures In Children ◽  
Limb Fractures

A survey of thrombosis prophylaxis use in patients with lower limb fractures

2004 ◽  
Vol 92 (11) ◽  
pp. 1166-1167 ◽  
Author(s):  
Francesco Dentali ◽  
Davide Imberti ◽  
Walter Ageno
Keyword(s):  
Lower Limb ◽  
Thrombosis Prophylaxis ◽  
Lower Limb Fractures ◽  
Limb Fractures

scholarly journals Time to debridement in open high-grade lower limb fractures and its effect on union and infections: A prospective study in a tropical setting

2020 ◽  
Vol 28 (1) ◽  
pp. 230949902090755
Author(s):  
Christina Marie Joseph ◽  
Thilak Samuel Jepegnanam ◽  
Boopalan Ramasamy ◽  
Vinoo Mathew Cherian ◽  
Manasseh Nithyananth ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Lower Limb ◽  
Short Form ◽  
Care Center ◽  
Tertiary Care ◽  
High Grade ◽  
Lower Limb Fractures ◽  
Sf 36 ◽  
Limb Fractures

Purpose: To prospectively evaluate whether time to debridement has any correlation with union, infection, and quality of life in high-grade lower limb fractures in a tropical setting. Methods: A prospective cohort study was conducted at a tertiary care center in South India. Two hundred fifty-four adult skeletally mature patients with 301 grade 3 fractures involving the femur, tibia, or fibula were recruited. The cohort was empirically divided into two groups (early and late) based on the time to debridement (less than or more than 12 h from injury). Outcome: The primary outcome was nonunion. Secondary outcomes were deep infection rates and patients’ quality of life. Short form-36 (SF-36) and short musculoskeletal functional assessment (SMFA) questionnaires were also used. Patients were followed up for 9 months. Results: The follow-up rate was 93%. The late group had a significantly higher risk of nonunion (odds ratio(OR): 6.5, 95% confidence interval (CI): 2.82–14.95) and infections (OR: 6.05, 95% CI: 2.85–12.82). There was a 4% increase in the infection risk for each hour of delay for the initial 50 h ( p < 0.0001). SF-36 and SMFA scores were superior in the early group ( p < 0.0001). Conclusion: The study contradicts findings reported in the literature from the West. Our study was in agreement with our hypothesis and proved that debridement within 12 h resulted in significantly lower rates of nonunion and infections and an overall improved quality of life in high-grade open lower limb fractures in a developing country. Level of evidence: Level II Trial registration: German Clinical Trials Register DRKS00015186

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