Biosynthesis and Characterization of Zinc Oxide Nanoparticles for the Systemic Treatment of Patients with Lymphoma in Nursing Care

2020 ◽  
Vol 12 (1) ◽  
pp. 137-143
Author(s):  
Lingling Meng ◽  
Lina Du ◽  
Yaqiong Shen ◽  
Shan Cong ◽  
Qiuyan Zhai ◽  
...  

Zinc oxide (ZnO) nanoparticles recently are of significant consideration because of their applications as nontoxic metal oxides. This study is mainly intended to improve a simple, efficient, and environment-friendly method for preparation of ZnO nanoparticles. This process has been developed based on plant-intervened synthesis by making use of microwave Saturejahortensis aqueous extract. We have further characterized the obtained Zinc oxide nanoparticles by using different techniques. Additionally, their cytotoxic potential was inspected via MTT assay against both B lymphoma, A20 and T lymphoma, EL4 cells lines. The zinc oxide nanoparticle exposed cells for about 24 h showed diminished cell viability in the tested cell lines where EL4 cells has been reduced to 75% of control after 24 h, whereas A20 cells were lowered to 68% of control. ZnO-NPs have proficiently hindered EL4 cell DNA synthesis at 100 μg concentration whereas completely blocked the DNA proliferation at about 50 g concentration. However, A20 cells besides presented similar propensity, thus exploring the ZnO-NPs potential to treat lymphomas.

RSC Advances ◽  
2016 ◽  
Vol 6 (111) ◽  
pp. 110108-110111 ◽  
Author(s):  
Zhenghui Liu ◽  
Huifang Zhou ◽  
Jiefeng Liu ◽  
Xudong Yin ◽  
Yufeng Mao ◽  
...  

Zinc oxide nanoparticles (ZnO NPs) have been monitored in wastewater treatment plants as their potential adverse effects on functional microorganisms have been causing increasing concern.


2016 ◽  
Vol 70 (11) ◽  
Author(s):  
Kateřina Hrdá ◽  
Jakub Opršal ◽  
Petr Knotek ◽  
Miloslav Pouzar ◽  
Milan Vlček

AbstractToxicity of zinc oxide nanoparticle (ZnO-NPs) powder and water soluble salt of Zn (ZnCl


RSC Advances ◽  
2016 ◽  
Vol 6 (81) ◽  
pp. 77752-77759 ◽  
Author(s):  
Jing-Kun Yan ◽  
Yao-Yao Wang ◽  
Lin Zhu ◽  
Jian-Yong Wu

Carboxylic curdlan (Cc), as a versatile β-1,3-polyglucuronic acid derivative, was used as both reducing and capping agents for the green synthesis of zinc oxide nanoparticles (ZnO NPs).


MRS Advances ◽  
2020 ◽  
Vol 5 (21-22) ◽  
pp. 1103-1112
Author(s):  
G.G. Welegergs ◽  
H.G. Gebretinsae ◽  
R. Akoba ◽  
N. Matinsie ◽  
Z. Y. Nuru ◽  
...  

AbstractBio-reduction agents are being explored to synthesised nanoparticles to minimize the effects of toxic chemicals. The present study was focused on green approach for the synthesis of zinc oxide nanoparticles using aqueous seeds extract of Papaver somniferum. The biosynthesised ZnO NPs (27.8nm) were characterized by using of spectroscopy and microscopy instruments. The surface morphology and the structural analysis confirms the formation of hexagonal nanostructure and a pure zincite nature of ZnO nanoparticles (NPs) respectively. The EDS spectrum confirms pure ZnO NPs were synthesised. From electrochemical properties, the CV indicates both anodic and cathodic sweep are quasi-reversible properties whose intensity increases with the scan rates. The bode plot shows the maximum angles of 74o which is an indication of a higher conductivity of ZnO NPs.


2020 ◽  
Vol 7 (5) ◽  
pp. 1431-1443
Author(s):  
Hong Zhang ◽  
Zhu Chen ◽  
Qing Huang

Zinc oxide nanoparticles (ZnO NPs) are one of the most abundantly applied nanomaterials in nanotechnology-based industries, and recent research continues to highlight their transformations and potential eco-toxicity especially to aquatic environment.


Author(s):  
Han Tao ◽  
Songshen Hu ◽  
Chuchu Xia ◽  
Mengyu Wang ◽  
Tonglin Wang ◽  
...  

Zinc oxide nanoparticles (ZnO NPs) are widely used in the manufacture of textile fibers, synthetic rubber, and paint. However, crop yields and quality are threatened by the increased use of...


2019 ◽  
Vol 2 (1) ◽  
pp. 42-52
Author(s):  
Abdur Rehman ◽  
Saira Ahmad ◽  
Abdul Mateen ◽  
Huma Qamar ◽  
Mudaber Ahmad Mubashar ◽  
...  

Nanotechnology is the science, engineering and technology conducted at the scale that ranges between 1-100 nanometers. For the bio-application, evolution of nanotechnology is creating the concern of scientists towards the synthesis of nanoparticles. The nanoparticles have unique characteristics as compare to bulk materials. Zinc oxide (ZnO) is a matchless semiconductor and it has been under investigation due to its wide range of applications in various areas like biomedical, electronics, material science and optics. In the present work synthesis of ZnO nanoparticles was carried out by using simple chemical approach, Sol-gel method for being effective and inexpensive, by employing zinc acetate dehydrate Zn (CH3CO2)2.2H2O as a precursor and sodium hydroxide (NaOH) starch as a constant agent. The structural properties of resultant zinc oxide nanoparticles were investigated by X-ray diffraction (XRD) technique. The XRD data confirmed the hexagonal wurtzite structure of ZnO powder confirmed by JCPDS 36-1451 data. Particles size was calculated by Scherrer formula and calculated size was 30.14 nm. These nanoparticles were investigated for inhibition zone of bacterial strain Escherichia coli, a gram-negative microbe, at various concentrations of ZnO nanoparticles. Zinc oxide nanoparticles were very proficient for inhibition of growth of bacterial strain E. coli. The mechanism of ZnO NPs for antibacterial activity is release of reactive oxygen species which not only hydrolyze cell wall but cell membrane and cellular components as well providing a potential bactericidal effect.


2021 ◽  
Author(s):  
Abdalrhaman Salih ◽  
Fahad Al Qurainy ◽  
Salim Khan ◽  
Mohamed Tarroum ◽  
Mohammad Nadeem ◽  
...  

Abstract Biosynthesized nanoparticles have played vital role recently, as suggested to be alternative to physical and chemical methods. In this study, biosynthesis of zinc oxide nanoparticles (ZnO NPs) were carried out using leaf extracts of Phoenix dactylifera and Zinc nitrate. The effect of ZnO nanoparticles on biomass and biochemical parameters was investigated. Biosynthesized ZnO nanostructure was characterized using X-ray diffraction (XRD), transmission electron microscopy (TEM), UV–visible spectrophotometer and Fourier transform infrared spectroscopy (FTIR). Which resulted in spherical shape with size ranging between 16 to 35 nm of Biosynthesized ZnO nanoparticles and UV absorption beak at 370.5 nm with clear peaks of functional groups. The impact of different concentrations (0.0 mg/L, 80 mg/L and 160 mg/L) of biosynthesized ZnO nanoparticles on biomass and bioactive compounds production of Juniperus Procera in vitro was investigated. The results showed that, biosynthesized ZnO NPs (80 mg /L and 160 mg/L) concentrations were boosted the growth of J. Procera with significantly compared to non-treated plants in vitro. The highest concentration (160mg/L) of ZnO NPs was enhanced the growth of plant at beginning period, one month later shoots became yellow and callus turned to be brownish. Moreover, the influence of ZnO NPs on phytochemical compounds in callus of Juniperus procera was examined using GC-MS analysis. The differences among treatments were recoded. Overall, zinc oxide nanoparticles substantially improved the growth of shoots and callus with increasing of biochemical parameters such as chlorophyll a, total phenolic and flavonoids contents, besides the total protein and, SOD, CAT and APX activity. ZnO NPs might be induced some phytochemical compounds as well as inhibit.


2020 ◽  
Vol 15 (11) ◽  
pp. 1412-1422
Author(s):  
Nishat Arshi ◽  
Y. Prashanthi ◽  
Tentu Nageswara Rao ◽  
Faheem Ahmed ◽  
Shalendra Kumar ◽  
...  

In this study, we report synthesis of Zinc oxide nanoparticles using simple chemical and green methods. The ZnO nanoparticles were synthesized using leaf extract of Azadirachta indica (neem) as reducing agent. The as obtained product was characterized by X-ray diffraction (XRD), Scanning Electron Microscopy (SEM), Energy dispersive X-ray analysis (EDAX) and TEM techniques. XRD analysis confirms that ZnO nanoparticles were crystalline having hexagonal Wurtzite structure with (1 0 0), (0 0 2), (1 0 1), (1 0 2), (1 1 0) and (1 1 2) planes. SEM analyses show that the as synthesized ZnO NPs were in the form of agglomerates and no other impurity peak was found in the EDS. TEM analyses confirm that the size of the nanoparticle was approx. 50 nm. Here in, we investigate the effect of chemical and green synthesized zinc oxide nanoparticles on germination and growth of lycopersicum esculentus (tomato) using petri plate seed germination method in loamy sand soil. The impact of concentration of applied ZnO nanoparticles via green synthesis and chemical methods were analyzed. Results revealed that green synthesized Zinc oxide nanoparticles showed maximum growth of seedling as compared to chemically synthesized Zinc oxide nanoparticles, bulk ZnO and control. After 50 days of tomato growth analysis, it was recognized that ZnO NPs can be a good green synthetic fertilizer by increasing shoot length, wet weight, dry weight and yield over conventional control. Hence, green method is found to be more effective.


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