Size- and Morphology-Dependent Antibacterial Properties of Cuprous Oxide Nanoparticle and Their Synergistic Antibacterial Effect

2016 ◽  
Vol 8 (5) ◽  
pp. 1074-1078 ◽  
Author(s):  
Boxi She ◽  
Xuejuan Wan ◽  
Jiaoning Tang ◽  
Yuanming Deng ◽  
Xiaofeng Zhou ◽  
...  
CrystEngComm ◽  
2015 ◽  
Vol 17 (2) ◽  
pp. 456-462 ◽  
Author(s):  
C. Tamames-Tabar ◽  
E. Imbuluzqueta ◽  
N. Guillou ◽  
C. Serre ◽  
S. R. Miller ◽  
...  

A novel biocompatible and bioactive zinc azelate metal–organic framework (BioMIL-5) was hydrothermally synthesized with interesting long-term antibacterial properties.


Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3747
Author(s):  
Weisheng Zhu ◽  
Luyao Wang ◽  
Qisi Li ◽  
Lizhi Jiao ◽  
Xiaokan Yu ◽  
...  

As one of the nanostructures with enzyme-like activity, nanozymes have recently attracted extensive attention for their biomedical applications, especially for bacterial disinfection treatment. Nanozymes with high peroxidase activity are considered to be excellent candidates for building bacterial disinfection systems (nanozyme-H2O2), in which the nanozyme will promote the generation of ROS to kill bacteria based on the decomposition of H2O2. According to this criterion, a cerium oxide nanoparticle (Nanoceria, CeO2, a classical nanozyme with high peroxidase activity)-based nanozyme-H2O2 system would be very efficient for bacterial disinfection. However, CeO2 is a nanozyme with multiple enzyme-like activities. In addition to high peroxidase activity, CeO2 nanozymes also possess high superoxide dismutase activity and antioxidant activity, which can act as a ROS scavenger. Considering the fact that CeO2 nanozymes have both the activity to promote ROS production and the opposite activity for ROS scavenging, it is worth exploring which activity will play the dominating role in the CeO2-H2O2 system, as well as whether it will protect bacteria or produce an antibacterial effect. In this work, we focused on this discussion to unveil the role of CeO2 in the CeO2-H2O2 system, so that it can provide valuable knowledge for the design of a nanozyme-H2O2-based antibacterial system.


2021 ◽  
Author(s):  
Wenxia Wang ◽  
Xiaoting Liang ◽  
Junxia Zheng ◽  
Qi He

Abstract In this work, we systematically investigate the sterilization effect of six kinds of commonly used commercial disinfectants, including the DuPont Virkon disinfectant, peracetic acid disinfectant, sodium hypochlorite, bromogeramine disinfectant, water-soluble allicin, and absolute ethanol, against the Escherichia coli, Staphylococcus aureus, Monilia albican and Clostridium sporogenes. The inhibition zone was used to qualitatively determine the antibacterial effects of the six disinfectants, and then the minimum two-fold dilution method was used to quantitatively determine the minimum inhibitory concentration and minimum bactericidal concentration of the six disinfectants on the four pathogens. The result illustrated that the antibacterial effect of peracetic acid disinfectant is the best, and clostridium sporogenes is the most sensitive to it, followed by bromogermine disinfectant, which can inhibit the four pathogenic bacteria at the concentration recommended by the manufacturer. The antibacterial effect of DuPont Virkon disinfectant, sodium hypochlorite, water-soluble allicin and absolute ethanol is not as good as expected, and cannot inhibit the four kinds of pathogenic bacteria at the recommended concentration. In summary, the antibacterial effect of peracetic acid disinfectant is the strongest, followed by the bromogermine disinfectant, DuPont Virkon disinfectant, sodium hypochlorite and water-soluble allicin. The absolute ethanol exhibits the worst antibacterial properties.


2018 ◽  
Vol 29 (20) ◽  
pp. 17622-17629 ◽  
Author(s):  
Sami AlYahya ◽  
B. Jansi Rani ◽  
G. Ravi ◽  
R. Yuvakkumar ◽  
A. Arun ◽  
...  

Materials ◽  
2020 ◽  
Vol 13 (21) ◽  
pp. 4953
Author(s):  
Iwona Tarach ◽  
Ewa Olewnik-Kruszkowska ◽  
Agnieszka Richert ◽  
Magdalena Gierszewska ◽  
Anna Rudawska

The aim of the study was to establish the influence of poly(ethylene glycol) (PEG) on the properties of potential biodegradable packaging materials with antibacterial properties, based on polylactide (PLA) and tea tree essential oil (TTO). The obtained polymeric films consisted of PLA, a natural biocide, and tea tree essential oil (5–20 wt. %) was prepared with or without an addition of 5 wt. % PEG. The PLA-based materials have been tested, taking into account their morphology, and their thermal, mechanical and antibacterial properties against Staphylococcus aureus and Escherichia coli. It was established that the introduction of a plasticizer into the PLA–TTO systems leads to an increase in tensile strength, resistance to deformation, as well an increased thermal stability, in comparison to films modified using only TTO. The incorporation of 5 wt. % PEG in the PLA solution containing 5 wt. % TTO allowed us to obtain a material exhibiting a satisfactory antibacterial effect on both groups of representative bacteria. The presented results indicated a beneficial effect of PEG on the antibacterial and functional properties of materials with the addition of TTO.


2017 ◽  
Vol Volume 12 ◽  
pp. 2553-2567 ◽  
Author(s):  
Bin Yu ◽  
Ye Wang ◽  
Xinlu Yu ◽  
Hongxia Zhang ◽  
Ji Zhu ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-9 ◽  
Author(s):  
Lydie Ploux ◽  
Mihaela Mateescu ◽  
Karine Anselme ◽  
Krasimir Vasilev

In a previous paper, we proposed new silver nanoparticles (SNPs) based antibacterial coatings able to protect eukaryotic cells from SNPs related toxic effects, while preserving antibacterial efficiency. A SNPs containing n-heptylamine (HA) polymer matrix was deposited by plasma polymerization and coated by a second HA layer. In this paper, we elucidate the antibacterial action of these new coatings. We demonstrated that SNPs-loaded material can be covered by thin HA polymer layer without losing the antibacterial activity to planktonic bacteria living in the near surroundings of the material. SNPs-containing materials also revealed antibacterial effect on adhered bacteria. Adhered bacteria number was significantly reduced compared to pure HA plasma polymer and the physiology of the bacteria was affected. The number of adhered bacteria directly decreased with thickness of the second HA layer. Surprisingly, the quantity of cultivable bacteria harvested by transfer to nutritive agar decreased not only with the presence of SNPs, but also in relation to the covering HA layer thickness, that is, oppositely to the increase in adhered bacteria number. Two hypotheses are proposed for this surprising result (stronger attachment or weaker vitality), which raises the question of the diverse potential ways of action of SNPs entrapped in a polymer matrix.


2020 ◽  
Author(s):  
Sara González-Fernández ◽  
Víctor Lozano-Iturbe ◽  
Beatriz García ◽  
Luis J. Andrés ◽  
Mª Fe Menéndez ◽  
...  

Abstract Background: The emergence and expansion of antibiotic resistance makes it necessary to have alternative anti-infective agents, among which silver nanoparticles (AgNPs) display especially interesting properties. AgNPs carry out their antibacterial action through various molecular mechanisms, and the magnitude of the observed effect is dependent on multiple, not fully understood, aspects, particle shape being one of the most important. In this article, we conduct a study of the antibacterial effect of a recently described type of AgNP: silver nanorings (AgNRs), making comparisons with other alternative types of AgNP synthesized in parallel using the same methodology. Results: When they act on planktonic forms, AgNRs produce a smaller effect on the viability of different bacteria than nanoparticles with other structures although their effect on growth is more intense over a longer period. When their action on biofilms is analyzed, AgNRs show a greater concentration-dependent effect. In both cases it was observed that the effect on inhibition depends on the microbial species, but not its Gram positive or negative nature. Growth patterns in silver-resistant Salmonella strains suggest that AgNRs work through different mechanisms to other AgNPs. The antibacterial effect is also produced to some extent by the conditioning of culture media or water by contact with AgNPs but, at least over short periods of time, this is not due to the release of Ag ions. Conclusions: AgNRs constitute a new type of AgNP, whose antibacterial properties depend on their shape, and is capable of acting efficiently on both planktonic bacteria and biofilms.


2020 ◽  
Vol 68 (4) ◽  
pp. 69-84
Author(s):  
Anna Romiszewska ◽  
Aneta Bombalska

The work presents a literature review on the use of graphene and its derivatives as the potential protection against bacterial microflora. Addressed issues relate to an attempt to explain the mechanisms of impact of graphene and its derivatives: graphene oxide (GO) and reduced graphene oxide (rGO) on the bacterial cells. Interaction of graphene materials (G, GO, rGO) with Gram(+) and Gram(-) were compared with regard to the concentration of the preparations, the nature of the culture medium and surface of graphene deposition. Issues related to the development of reactive oxygen species (ROS) were discussed, the effect of sharp edges of GM’s (nano-knife), biofilm formation and the potential application of graphene in nanomedicine. Keywords: biomedicine, graphene, graphene oxide antibacterial effect, biofilm


Author(s):  
ERLINA HASRIATI ◽  
HARU SETYO ANGGANI ◽  
MARIA PURBIATI ◽  
ENDANG WINIATI BACHTIAR

Objective: Inflammation is one of the most common complications observed when using orthodontic miniscrews. Chlorhexidine mouthwash can beused to prevent and reduce the degree of inflammation, but long-term use of this solution may lead to some side effects. This study sought to evaluatethe peri-miniscrew antibacterial effect of 1% chitosan, a biomaterial with antibacterial properties, relative to 0.2% chlorhexidine mouthwash.Methods: A randomized, double-blind clinical trial was conducted at the Dental Teaching Hospital and Oral Biology Research Laboratory at theUniversity of Indonesia from February to June 2019. Thirty subjects (25 females and five males) were randomly assigned to rinse with 1% chitosan(n=10), 0.2% chlorhexidine digluconate (n=10), and Aquadest (n=10) in addition to their usual oral hygiene procedure for 4 days. Peri-miniscrewclinical inflammation signs were recorded and peri-miniscrew plaque collected before and after 4 days of rinsing. The total bacterial and red-complexbacteria count in plaque samples were evaluated by a real-time polymerase chain reaction.Results: Chitosan and chlorhexidine showed antibacterial activity, reducing total bacterial count around orthodontic miniscrews (p<0.05). Theantibacterial activity of chitosan on total bacteria was not significantly different from that of chlorhexidine (p≥0.05). Regarding the antibacterialactivity of chitosan on red-complex bacteria, the best result seen was a 58% bacteria count reduction in Tannerella denticola.Conclusion: Chitosan has potential antibacterial activity and could be used in mouthwash to maintain peri-miniscrew hygiene.


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