Magnetic Field-Induced Accentuation of Drug Release from Core/Shell Magnetic Mesoporous Silica Nanoparticles for Anticancer Treatment

2016 ◽  
Vol 16 (4) ◽  
pp. 4195-4199 ◽  
Author(s):  
Nikola Ž Knežević
Keyword(s):  
Magnetic Field ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Hela Cells ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carriers ◽  
Core Shell ◽  
Delivery Method ◽  
Anticancer Treatment ◽  
Magnetic Mesoporous Silica

Drug (9-aminoacridine) loaded core/shell magnetic iron oxide-containing mesoporous silica nanoparticles (MMSN) were treated with HeLa cells and the drug carriers were agitated by exposure to magnetic field. Viability studies show the applicability of drug loaded magnetic material for anticancer treatment, which is enhanced upon stimulation with magnetic field. Confocal micrographs of fluorescein grafted MMSN-treated HeLa cells confirmed the ability of magnetic field to concentrate the synthesized material in the exposed area of the cells. The synthesized material and the applied drug delivery method may find application in magnetic field-responsive targeted treatment of cancer.

Fucoidan-coated core–shell magnetic mesoporous silica nanoparticles for chemotherapy and magnetic hyperthermia-based thermal therapy applications

2017 ◽  
Vol 41 (24) ◽  
pp. 15334-15346 ◽  
Author(s):  
Madhappan Santha Moorthy ◽  
Bharathiraja Subramanian ◽  
Manivasagan Panchanathan ◽  
Sudip Mondal ◽  
Hyehyun Kim ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Magnetic Hyperthermia ◽  
Thermal Therapy ◽  
Core Shell ◽  
Magnetic Mesoporous Silica

Fucoidan-coated FeNP@SiOH@Fuc NPs have been proposed for chemotherapy and thermal therapy applications in emerging cancer therapy.

Synthesis, decoration, and cellular effects of magnetic mesoporous silica nanoparticles

RSC Advances ◽  
2016 ◽  
Vol 6 (62) ◽  
pp. 57275-57283 ◽  
Author(s):  
J. L. Nyalosaso ◽  
E. Rascol ◽  
C. Pisani ◽  
C. Dorandeu ◽  
X. Dumail ◽  
...  
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Magnetic Core ◽  
Core Shell ◽  
Shell Nanoparticles ◽  
Cellular Effects ◽  
Core Shell Nanoparticles ◽  
Magnetic Mesoporous Silica

Synthesis of magnetic core@shell nanoparticles with different coatings and the study of their uptake by cells.

Construction of polymer coated core–shell magnetic mesoporous silica nanoparticles with triple responsive drug delivery

2017 ◽  
Vol 8 (38) ◽  
pp. 5852-5864 ◽  
Author(s):  
Mohammad Hegazy ◽  
Pei Zhou ◽  
Guangyu Wu ◽  
Lei Wang ◽  
Nahla Rahoui ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Drug Delivery Systems ◽  
Mesoporous Silica Nanoparticles ◽  
Delivery Systems ◽  
Core Shell ◽  
On Demand ◽  
Magnetic Mesoporous Silica

Multi-responsive drug delivery systems are playing a very important role in nanomedicine, as they can feature as smart carriers releasing their payload on demand.

Exploiting mesoporous silica nanoparticles as versatile drug carriers for several routes of administration

2021 ◽  
Vol 312 ◽  
pp. 110774
Author(s):  
Rafael Miguel Sábio ◽  
Andréia Bagliotti Meneguin ◽  
Aline Martins dos Santos ◽  
Andreia Sofia Monteiro ◽  
Marlus Chorilli
Keyword(s):  
Mesoporous Silica ◽  
Silica Nanoparticles ◽  
Mesoporous Silica Nanoparticles ◽  
Drug Carriers ◽  
Routes Of Administration
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