In Vitro Evaluation and Finite Element Simulation of Drug Release from Polydiacetylene-Polyethylene Glycol Stearate Nanovesicles

2012 ◽  
Vol 12 (1) ◽  
pp. 245-251 ◽  
Author(s):  
Caixin Guo ◽  
Like Zeng ◽  
Shaoqin Liu ◽  
Qi Chen ◽  
Zhifei Dai ◽  
...  
Keyword(s):  
Finite Element ◽  
Polyethylene Glycol ◽  
Drug Release ◽  
Finite Element Simulation ◽  
Element Simulation

BIOMECHANICAL BEHAVIOUR OF BOVINE SKIN: AN EXPERIMENT-THEORY INTEGRATION AND FINITE ELEMENT SIMULATION

2015 ◽  
Vol 76 (10) ◽  
Author(s):  
Nor Fazli Adull Manan ◽  
Jamaluddin Mahmud ◽  
Aidah Jumahat
Keyword(s):  
Finite Element ◽  
Finite Element Simulation ◽  
Deformation Behaviour ◽  
Element Model ◽  
Tensile Tests ◽  
Theory Integration ◽  
Element Simulation ◽  
Knowledge Enhancement ◽  
First Time

This paper for the first time attempts to establish the biomechanical characteristics of bovine skin via experiment-theory integration and finite element simulation. 30 specimens prepared from fresh slaughtered bovine were uniaxially stretched in-vitro using tensile tests machine. The experimental raw data are then input into a Matlab programme, which quantified the hyperelastic parameters based on Ogden constitutive equation. It is found that the Ogden coefficient and exponent for bovine skin are μ = 0.017 MPa and α = 11.049 respectively. For comparison of results, the quantified Ogden parameters are then input into a simple but robust finite element model, which is developed to replicate the experimental setup and simulate the deformation of the bovine skin. Results from experiment-theory integration and finite element simulation are compared. It is found that the stress-stretch curves are close to one another. The results and finding prove that the current study is significant and has contributed to knowledge enhancement about the deformation behaviour of bovine skin.

Finite Element Simulation of Tire-Rim Interface

1989 ◽  
Vol 17 (4) ◽  
pp. 305-325 ◽  
Author(s):  
N. T. Tseng ◽  
R. G. Pelle ◽  
J. P. Chang
Keyword(s):  
Finite Element ◽  
Finite Element Model ◽  
Finite Element Simulation ◽  
Contact Pressure ◽  
Element Model ◽  
Experimental Measurements ◽  
Inflation Pressure ◽  
Interference Fit ◽  
Element Simulation ◽  
Rubber Composite

Abstract A finite element model was developed to simulate the tire-rim interface. Elastomers were modeled by nonlinear incompressible elements, whereas plies were simulated by cord-rubber composite elements. Gap elements were used to simulate the opening between tire and rim at zero inflation pressure. This opening closed when the inflation pressure was increased gradually. The predicted distribution of contact pressure at the tire-rim interface agreed very well with the available experimental measurements. Several variations of the tire-rim interference fit were analyzed.

Numerical Simulation of Tire Sliding Events Involving Impacts with Holes and Bumps

1986 ◽  
Vol 14 (2) ◽  
pp. 125-136 ◽  
Author(s):  
Y. Nakajima ◽  
J. Padovan
Keyword(s):  
Numerical Simulation ◽  
Finite Element ◽  
Finite Element Simulation ◽  
Full Range ◽  
Arbitrary Geometry ◽  
Operating Environments ◽  
Element Simulation ◽  
Simulation Scheme

Abstract This paper extends the finite element simulation scheme to handle the problem of tires undergoing sliding (skidding) impact into obstructions. Since the inertial characteristics are handled by the algorithm developed, the full range of operating environments can be accommodated. This includes the treatment of impacts with holes and bumps of arbitrary geometry.

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