Apta-Biosensors for Nonlabeled Real Time Detection of Human IgE Based on Carbon Nanotube Field Effect Transistors

2011 ◽  
Vol 11 (5) ◽  
pp. 4182-4187 ◽  
Author(s):  
Jun Pyo Kim ◽  
Seunghun Hong ◽  
Sang Jun Sim
Keyword(s):  
Carbon Nanotube ◽  
Real Time ◽  
Field Effect ◽  
Field Effect Transistors ◽  
Real Time Detection

Liquid-phase alkali-doping of individual carbon nanotube field-effect transistors observed in real-time

Carbon ◽  
2011 ◽  
Vol 49 (15) ◽  
pp. 5283-5291 ◽  
Author(s):  
Peerapong Yotprayoonsak ◽  
Konsta Hannula ◽  
Tanja Lahtinen ◽  
Markus Ahlskog ◽  
Andreas Johansson
Keyword(s):  
Carbon Nanotube ◽  
Liquid Phase ◽  
Real Time ◽  
Field Effect ◽  
Field Effect Transistors ◽  
Alkali Doping

Label-Free and Real-Time Detection of Avian Influenza Using Nanowire Field Effect Transistors

2015 ◽  
Vol 11 (9) ◽  
pp. 1640-1643 ◽  
Author(s):  
Jae-Hyuk Ahn ◽  
Maesoon Im ◽  
Tae Jung Park ◽  
Sang Yup Lee ◽  
Yang-Kyu Choi
Keyword(s):  
Avian Influenza ◽  
Real Time ◽  
Field Effect ◽  
Field Effect Transistors ◽  
Label Free ◽  
Real Time Detection

Real-time selective monitoring of allergenic Aspergillus molds using pentameric antibody-immobilized single-walled carbon nanotube-field effect transistors

RSC Advances ◽  
2015 ◽  
Vol 5 (20) ◽  
pp. 15728-15735 ◽  
Author(s):  
Joon-Hyung Jin ◽  
Junhyup Kim ◽  
Taejin Jeon ◽  
Su-Kyoung Shin ◽  
Jong-Ryeul Sohn ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Real Time ◽  
Field Effect ◽  
Field Effect Transistors ◽  
Immunoglobulin M ◽  
Detection Range ◽  
Single Walled Carbon Nanotube ◽  
Fungal Allergens ◽  
Chemical Gating ◽  
Selective Monitoring

A SWNT-FET directly functionalized with immunoglobulin M shows a wide detection range from sub-picomolar to micromolar with an excellent sensitivity due to chemical gating in selective monitoring of fungal allergens.

Peptide Nucleic Acid–Modified Carbon Nanotube Field-Effect Transistor for Ultra-Sensitive Real-Time Detection of DNA Hybridization

2005 ◽  
Vol 1 (1) ◽  
pp. 065-070 ◽  
Author(s):  
Kagan Kerman ◽  
Yasutaka Morita ◽  
Yuzuru Takamura ◽  
Eiichi Tamiya ◽  
Kenzo Maehashi ◽  
...  
Keyword(s):  
Carbon Nanotube ◽  
Nucleic Acid ◽  
Real Time ◽  
Dna Hybridization ◽  
Peptide Nucleic Acid ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Effect Transistor ◽  
Real Time Detection

A Dual Function Electro-Optical Silicon Field-Effect Transistor Molecular Sensor

2021 ◽  
Author(s):  
Pradhana Jati Budhi Laksana ◽  
Li-Chu Tsai ◽  
Tsai-Yin Wei ◽  
Pei-Chi Lan ◽  
Kuei-Shu Chang-Liao ◽  
...  
Keyword(s):  
Real Time ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Field Effect Transistors ◽  
Dual Function ◽  
High Charge ◽  
Molecular Sensor ◽  
Effect Transistor ◽  
Real Time Detection ◽  
Optical Silicon

We propose and demonstrate an approach that utilizes field-effect transistors (FETs) for real-time detection of interactions between molecules. In this approach, FET based sensors utilize two unique functions, high charge...

scholarly journals High-Throughput Peptide Epitope Mapping Using Carbon Nanotube Field-Effect Transistors

2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Steingrimur Stefansson ◽  
Martha Knight ◽  
Hena H. Kwon ◽  
Lára A. Stefansson ◽  
Saeyoung Nate Ahn
Keyword(s):  
Carbon Nanotube ◽  
Real Time ◽  
High Throughput ◽  
Field Effect ◽  
Epitope Mapping ◽  
Field Effect Transistors ◽  
Peptide Library ◽  
Label Free ◽  
Peptide Epitope ◽  
Binding Data

Label-free and real-time detection technologies can dramatically reduce the time and cost of pharmaceutical testing and development. However, to reach their full promise, these technologies need to be adaptable to high-throughput automation. To demonstrate the potential of single-walled carbon nanotube field-effect transistors (SWCNT-FETs) for high-throughput peptide-based assays, we have designed circuits arranged in an 8 × 12 (96-well) format that are accessible to standard multichannel pipettors. We performed epitope mapping of two HIV-1 gp160 antibodies using an overlapping gp160 15-mer peptide library coated onto nonfunctionalized SWCNTs. The 15-mer peptides did not require a linker to adhere to the non-functionalized SWCNTs, and binding data was obtained in real time for all 96 circuits. Despite some sequence differences in the HIV strains used to generate these antibodies and the overlapping peptide library, respectively, our results using these antibodies are in good agreement with known data, indicating that peptides immobilized onto SWCNT are accessible and that linear epitope mapping can be performed in minutes using SWCNT-FET.

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